Doctor insights on:
Does Sjogrens Syndrome Go Hand In Hand With Lupus
Autoimmune disease: The most common symptoms in Sjögren's syndrome are dry eyes and dry mouth because white blood cells get "confused" and attack and destroy glands in the body that make tears, saliva, vaginal secretions, and other secretions.Inflammation in Sjögren's can cause rashes or arthritis, and even liver, kidney or brain disease. Can also cause saliva gland cancer (lymphoma), so getting treated is important. ...Read moreSee 1 more doctor answer
Does sjogrens syndrome come in flares like lupus? What is easier to control-lupus that affects organs or sjogrens that affects organs ?
Yes: Sjogren's can have flares just like sle and there is frequently overlap between the two. Neither is desirable when organ involvement occurs since these are very difficult to treat or reverse. ...Read more
Possibly: Sjogrens syndrome will typically presenst with dry eyes and dry mouth. It is not uncommon for sjogrens to occur with other rheumatic illnesses such as lupus. We call this secondary sjogrens and tends to cause the above issues. We still treat the underlying illness and in your case lupus. Sjogrens can occur by itself and we call this primary sjogrens and may have more issues then secondary sjogrens. ...Read more
They: Sjogren's is in some ways a milder disease but it can have significant organ involvement. Sjogrens's typically affects the moisture glands in your body causing dryness, whereas lupus does not. Sometimes they can coexist together. Lupus can have significant organ involement compared to sjogren's and often is worse than sjogrens in terms of organ involvement. ...Read more
They are similar: Both are autoimmune diseases and to varying degree, they have overlapping symptoms. Patients with lupus can have symptoms of sjogrens and vice versa. Both can lead to very serious, life threatening disease. More often, however, they are relatively well managed. In summary, severe lupus is probably worse than severe sjogrens, but there are exceptions. ...Read more
MD says I have primary lupus &secondary sjogrens. My chart says lupus-sjogrens overlap syndrome.Is there a difference between listing them separately?
No: Your treatment will be the same. Kudos for taking charge and reading the documentation carefully! ...Read more
Any more risks with having lupus/sjogrens overlap syndrome than having lupus alone? Is it possible with good diet & exercise to be very healthy?
Carious Lesions: Xerostomia is one of the components of sjogrens syndrome. The best thing to do would be supplement your oral hygiene regimen with Fluoride based agents and if you want to be proactive xylitol based gums, rinses etc would be helpful in keeping you cavity free. See your dentist for regular checkups. ...Read moreSee 2 more doctor answers
No data to say so: I just did a search of all medical literature published from the 1970's on and did not find a single article connecting the two. ...Read more
Essentially normal: With appropriate treatment should be essentially normal. ...Read more
One of these forms: Ss related kidney disease would show up in biopsy & lab work on blood & urine: 1. A tubular interstitial nephritis biopsy revealing lymphocytes infiltrating normal surrounding kidney tissue. 2. Dangerous electrolyte imbalances in blood from inadequate acid removal from urine. 3. Blood, protein & other waste products in the urine due to decreased ability of the kidney to filter well. ...Read more
No: Your immune system with any autoimmune disease is in overdrive. With sjogrens syndrome salivary tissues are affected. This does not mean it completely destroys your salivary glands. Most people will have a dry mouth. Try drinking a lot of water to keep the dryness to a minimum. ...Read moreSee 1 more doctor answer
Bx and lab.: I do minor salivary gland bx, and really heavily on lab tests, looking for the presence of ss-a and ss-b autoantibodies. Almost 50% of sjogren's patients have a positive rf. Eelvations of gammaglobulins are common, especially IgG and igm. There is some heredebiity to this condition, albeit weaker than many forms of arthritis. ...Read moreSee 1 more doctor answer
Sjogren's: Sjogren's is the most common of the (so called) connective tissue diseases in the lupus family. Ucsd and scripp's cliic researches suggest on the basis of autoimmine blood tests run on blood donors, 1/300 may have it, although it is closer to 1/500. Variable in severity, it causes loss of water secretions in mouth, eyes, colon, even perspiration, with time. Associated with ss-a, b antibodies. ...Read more