Doctor insights on:
Does Rheumatoid Arthritis Always Show Up In Blood Work
Possible negative: Rheumatoid factor (rf) and cyclic citrinullated peptide (ccp) are the two tests that help confirm a diagnosis of rheumatoid arthritis. Other tests are done to measure inflammation, determine which drugs may be used, etc. About 15% of people with RA are rf and ccp negative. ...Read more
A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
Can it be possible to have juvenile rheumatoid arthritis as a kid but not have it show up in blood work as an adult?
Yes, no blood test..: There is no blood test for juvenile rheumatoid/idiopathic arthritis. Kids can have all completely normal labs and still have very active disease. It is a clinical diagnosis based on inflammation of the synovial cells lining the joints that can be seen as joint swelling much of the time on exam. Kids never "outgrow" jia/jra. They have it for life, even as adults with flares of arthritis (not ra). ...Read more
Yes: In ~ 40% of people with bona fide Rheumatoid Arthritis (RA) the RHEUMATOID FACOR (RF) test will never be positive. Non specific tests that measure inflammation (WESR/CRP) may also be normal in early RA. The CCP test, however, is very sensitive in early RA ; ~ 80/90% of the time it will be (+). One of the "best" tests is to see a doctor who can recognize the early signs of RA: synovitis of joints. ...Read more
Is it possible to have rheumatoid arthritis with a normal RA factor? My labs show my level was 12.6 but I have the symptoms of the condition.
Hum: In rheumatoid arthritis you might have for other reason inflammation , but muscle contraction is really not a feature of rheumatoid arthritis , flexure contracture might occurs , that are reducciton on the lengh of the tendons with dys functionallity those have to be evaluated and specific therapy instituted. Some patients with rheumatoid arthritis suffer of fybromyalgia, and have contractures. ...Read more
Yes.: My colleagues believe it is the first choice (acr and eular), but while I use it as a second or third drug, the benefit/risk ratio is incredibly good. Methotrexate has little or no justification to be taken orally though. Unpredictable absorption, stomach concenbration build up, and going to the liver on first-pass! the liver sees 600x the ultimate concentration in the blood. ...Read more
Is it possible for someone who's 50 to have rheumatoid arthritis even if the blood work n X-ray was negative..??
No: There is a group of diseases called "seronegative arthritis." In this case, the lab tests do not demonstrate rheumatoid arthritis but do often show elevated levels of inflammation in the body. These diseases can have some similar symptoms to rheumatoid arthritis and are often treated using the same medications. ...Read more
Plaquenil (hydroxychloroquine). When does it start to work? When will it be fully working n treating for rheumatoid arthritis? When will i notice improvement?
Yes: Indocin is a non steroidal anti-inflammatory drug (NSAID) like Motrin. It can help the pain and stiffness but does slow down joint damage. (disease progression) Asulfadine is a diseases modifying medication (DMARD). This class of drugs can help pain and stiffness and also help slow down disease progression. Other commonly used DMARDS include: methotrexate, Arava, (leflunomide) and plaquenil. ...Read more
Erythrocyte sedimentation rate.High
rheumatoid factor cold be present
cyclic citrullinated peptide (ccp). Like the rheumatoid factor, the ccp is another antibody that may be found in the blood of adults with rheumatoid arthritis. ...Read more
M58, what will differentially diagnose multiple multiple myeloma and rheumatoid arthritis, simple economical blood work. ?
Not so easy: Ra is a disease diagnosed bya qualified based on blood work and clinical symptoms and signs. It can be made by your pcp but your best bet would be to see a rheumatologist. For multiple myeloma, the initial work up requires both blood and urine tests to screen for the proteins produced by the disease. Neither condition can be made by bloodwork alone. You need to see a physician. ...Read more
How often should blood work and xrays be done? For rheumatoid arthritis. I feel like my doc is ordering excessive labs and xrays.
I can not answer--: -this 4 U. I assume U R Cing a rheumatologist. Confront him about this in a sweet & gentle way so as not 2 offend. Make it casual. Some MD'S R sensitive & so try not 2 make it an attack on judgment buy more in a curious manner. It is Ur right 2 know. ...Read more
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