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Doctor insights on: Does Rheumatoid Arthritis Always Show Up In Blood Work

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Does rheumatoid arthritis always show up in blood work?

Does rheumatoid arthritis always show up in blood work?

Possible negative: Rheumatoid factor (rf) and cyclic citrinullated peptide (ccp) are the two tests that help confirm a diagnosis of rheumatoid arthritis. Other tests are done to measure inflammation, determine which drugs may be used, etc. About 15% of people with RA are rf and ccp negative. ...Read more

Dr. Thomas Namey
2,420 doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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Can it be possible to have juvenile rheumatoid arthritis as a kid but not have it show up in blood work as an adult?

Can it be possible to have juvenile rheumatoid arthritis as a kid but not have it show up in blood work as an adult?

Yes, no blood test..: There is no blood test for juvenile rheumatoid/idiopathic arthritis. Kids can have all completely normal labs and still have very active disease. It is a clinical diagnosis based on inflammation of the synovial cells lining the joints that can be seen as joint swelling much of the time on exam. Kids never "outgrow" jia/jra. They have it for life, even as adults with flares of arthritis (not ra). ...Read more

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Can rheumatoid arthritis take time to show in blood work?

Can rheumatoid arthritis take time to show in blood work?

Yes: In ~ 40% of people with bona fide Rheumatoid Arthritis (RA) the RHEUMATOID FACOR (RF) test will never be positive. Non specific tests that measure inflammation (WESR/CRP) may also be normal in early RA. The CCP test, however, is very sensitive in early RA ; ~ 80/90% of the time it will be (+). One of the "best" tests is to see a doctor who can recognize the early signs of RA: synovitis of joints. ...Read more

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Is it possible to have rheumatoid arthritis and it not show up in any bloodwork?

Is it possible to have rheumatoid arthritis and it not show up in any bloodwork?

Yes but there are ot: other criteria and tests a rheumatologist has to use to assess. One other thing to ask about is a so called rheumatoid negative spondylarthrophy, that can accompany IBS, psoriasis, and other seemingly unrelated diseases. there are other tests for these too ...Read more

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Will an ANA test show if I have rheumatoid arthritis?

Will an ANA test show if I have rheumatoid arthritis?

No: The ANA is a screening test for lupus. The ccp antibody is the test you want for ra. ...Read more

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Is it possible to have rheumatoid arthritis with a normal RA factor? My labs show my level was 12.6 but I have the symptoms of the condition.

Is it possible to have rheumatoid arthritis with a normal RA factor? My labs show my level was 12.6 but I have the symptoms of the condition.

Unlikely but possibl: Unlikely, but possibile. Get a ccp antibody, much more specific! but some rfs are of the igg class. Conventional assays miss these. See a rheumatologist. ...Read more

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What work best to treat rheumatoid arthritis?

What work best to treat rheumatoid arthritis?

DMARDs: Disease modifying meds (dmards) are the meds of choice as their can prevent damage, deformity and disability. Rheumatologists usually start with Methotrexate and add other meds such as tnf agents if necessary. Early treatment is essential. ...Read more

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Which muscle relaxer works best for rheumatoid arthritis?

Hum: In rheumatoid arthritis you might have for other reason inflammation , but muscle contraction is really not a feature of rheumatoid arthritis , flexure contracture might occurs , that are reducciton on the lengh of the tendons with dys functionallity those have to be evaluated and specific therapy instituted. Some patients with rheumatoid arthritis suffer of fybromyalgia, and have contractures. ...Read more

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Do tnf blockers work for people with rheumatoid arthritis?

Do tnf blockers work for people with rheumatoid arthritis?

Yes.: But other drugs should be tried first, and they usually work. Methotrexate failure is usually a requisite. ...Read more

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Does homeopathy work in treating psoriatic or rheumatoid arthritis?

Does homeopathy work in treating psoriatic or rheumatoid arthritis?

No, not alone: Both psoriatic and rheumatoid arthritis have inflammation, which can be helped by homeopathy, but unlikely controlled enough to avoid the joint damage if things are not controlled. Smoking hurts both. Seek a homeopathic physician to guide you. ...Read more

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Methotrexate for rheumatoid arthritis dose it work and anyone had side effects?

Methotrexate for rheumatoid arthritis dose it work and anyone had side effects?

Yes.: My colleagues believe it is the first choice (acr and eular), but while I use it as a second or third drug, the benefit/risk ratio is incredibly good. Methotrexate has little or no justification to be taken orally though. Unpredictable absorption, stomach concenbration build up, and going to the liver on first-pass! the liver sees 600x the ultimate concentration in the blood. ...Read more

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Is it possible to have rheumatoid arthritis without it showing up in blood work?

Yes: Labs and xrays ECT are by no means always correct
there are many other types of arthritis too

discuss in detail with your doctor and or your rheumatologist. ...Read more

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Is it possible for someone who's 50 to have rheumatoid arthritis even if the blood work n X-ray was negative..??

Is it possible for someone who's 50 to have rheumatoid arthritis even if the blood work n X-ray was negative..??

No: There is a group of diseases called "seronegative arthritis." In this case, the lab tests do not demonstrate rheumatoid arthritis but do often show elevated levels of inflammation in the body. These diseases can have some similar symptoms to rheumatoid arthritis and are often treated using the same medications. ...Read more

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Plaquenil (hydroxychloroquine). When does it start to work? When will it be fully working n treating for rheumatoid arthritis? When will i notice improvement?

Plaquenil (hydroxychloroquine).  When does it start to work? When will it be fully working n treating for rheumatoid arthritis? When will i notice improvement?

Takes time: Plaquenil (hydroxychloroquine) often takes at least 1-2 months for significant improvement with rheumatoid arthritis -- sometimes it can take up to 6 months for full effect. Be patient. If no improvement at all in 2-3 months though i would check with your doctor. ...Read more

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What causes a rheumatoid arthritis to show up?

What causes a rheumatoid arthritis to show up?

We don't know....: Prior infectious mononucleosis appears to be necessary. Age and sex are important. Uncommon before 18, usually age of onset 35, and 7-10 x more likely in women than men. The cxuase remanes unknown. Good treatments exist to put virtually all patients in remission. ...Read more

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Endocin &/or azulphadin for rheumatoid arthritis, do these work?

Endocin &/or azulphadin for rheumatoid arthritis, do these work?

Yes: Indocin is a non steroidal anti-inflammatory drug (NSAID) like Motrin. It can help the pain and stiffness but does slow down joint damage. (disease progression) Asulfadine is a diseases modifying medication (DMARD). This class of drugs can help pain and stiffness and also help slow down disease progression. Other commonly used DMARDS include: methotrexate, Arava, (leflunomide) and plaquenil. ...Read more

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What is abnormal in juvenile rheumatoid arthritis in blood work?

What is abnormal in juvenile rheumatoid arthritis in blood work?

Many thinks: Erythrocyte sedimentation rate.High
c-reactive protein.High
anti-nuclear antibody.High
rheumatoid factor cold be present
cyclic citrullinated peptide (ccp). Like the rheumatoid factor, the ccp is another antibody that may be found in the blood of adults with rheumatoid arthritis. ...Read more

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M58, what will differentially diagnose multiple multiple myeloma and rheumatoid arthritis, simple economical blood work. ?

M58, what will differentially diagnose multiple multiple myeloma  and rheumatoid arthritis, simple economical blood work.  ?

Not so easy: Ra is a disease diagnosed bya qualified based on blood work and clinical symptoms and signs. It can be made by your pcp but your best bet would be to see a rheumatologist. For multiple myeloma, the initial work up requires both blood and urine tests to screen for the proteins produced by the disease. Neither condition can be made by bloodwork alone. You need to see a physician. ...Read more

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How often should blood work and xrays be done? For rheumatoid arthritis. I feel like my doc is ordering excessive labs and xrays.

How often should blood work and xrays be done?  For rheumatoid arthritis.  I feel like my doc is ordering excessive labs and xrays.

I can not answer--: -this 4 U. I assume U R Cing a rheumatologist. Confront him about this in a sweet & gentle way so as not 2 offend. Make it casual. Some MD'S R sensitive & so try not 2 make it an attack on judgment buy more in a curious manner. It is Ur right 2 know. ...Read more

Dr. Mark Pack
40 doctors shared insights

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more


Dr. Robert Lowe
1,553 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more