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Doctor insights on: Does Prednisone Make You Tired

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Dr. Daniel Bauman
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Dr. Thomas Namey
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Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


Dr. Daniel Bauman
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I feel very tired all the time. I am taking 5mg prednisone daily plus 2x seretide 500. Is tiredness a side effect?

I feel very tired all the time. I am taking 5mg prednisone daily plus 2x seretide 500.  Is tiredness a side effect?

Not likely . . .: Seretide is sold in states as serevent (salmeterol), which along w/prednisone, suggests that you have either COPD or asthma. Feeling tired all the time isn't really a side effect of these meds (if anything, it's opposite effect of what's experienced w/prednisone). Therefore you need to go see your family doc (or who prescribed these meds) and tell him/her what you wrote. Perhaps not enough o2. ...Read more

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Why does prednisone cause excessive urination and sugar craving and excess tiredness? I get this every time I take it. Anyway to curb sx?

Why does prednisone cause excessive urination and sugar craving and excess tiredness?  I get this every time I take it.  Anyway to curb sx?

Different Steroid: Steroids influence many of your bodies functions strongly and broadly. If you are having consistent problems with side effects from the prednisone. Talk to your doctor about other options when you require treatment with steroids. ...Read more

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Can prednisone make you tired?

Can prednisone make you tired?

Yes, but...: Different people have different reactions to prednisone. Prednisone can make a person tired, fussy, excited, irritable, etc... However, many illnesses can make a person tired, so one cannot simply blame tiredness on the Prednisone (the doctor can consider the various causes of the tiredness). ...Read more

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Can prednisone make a person tired?

Yes but why on pred: It depends why you are on prednisone. That may be the reason for your fati gue. Prednisone can interfere with quality sleep and this can cause fatigue. You can discuss your fatigue with your physician. Often daytime fatigue is due to poor quality of sleep and a sleep study may help. ...Read more

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Dr. Daniel Bauman
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I feel tired and sad all the time since my diagnosis. Can mtx and prednisone make you feel this way?

I feel tired and sad all the time since my diagnosis. Can mtx and prednisone make you feel this way?

Treatment effect: Yes. Steroids can affect yr psyche and mental well being. Discuss with your doctor. At age 23, you don't need those 2 meds in my opinion. They can have some serious long term effects. ...Read more

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Can prednisone cause someone to become extremely tired out of nowhere?

Can prednisone cause someone to become extremely tired out of nowhere?

Yes, talk to doc: High-dose prednisone can cause many side effects. You may get hyper or very tired, euphoric or depressed. When it is stopped, you may feel even more tired. If you have been on prednisone for many months, your adrenal gland may stop working leading to a transient adrenal failure. Note also that the disease condition for which prednisone is prescribed may be be a factor. Call your doc. ...Read more

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Dizziness,vision blurriness, & confusion that lasts hours or days on/off x 3 yrs.Prednisone clears up sx. MD wants EEG.Worth it?Tired of useless tests

Dizziness,vision blurriness, & confusion that lasts hours or days on/off x 3 yrs.Prednisone clears up sx. MD wants EEG.Worth it?Tired of useless tests

Yes: These symptoms sound like central (brain) disorder. The EEG may give important information. The fact that prednisone helped may indicate an inflammatory disorder. See a neurologist. The fact that the symptoms have been present for 3 years strongly indicates that you should have an MRI of the brain. All these symptoms for such a long time really needs a neurological diagnosis ASAP. ...Read more

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Dr. John Feola
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Dr. Daniel Bauman
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