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Doctor insights on: Does Prednisone Make You Tired

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Dr. Thomas Namey
2,560 Doctors shared insights

Prednisone (Definition)

Prednisone is a synthetic cortisone. The body makes cortisone, a natural hormone made in adrenal glands. The body converts it to Hydrocortisone to become active. 25 mg of cortisone has about same effect as 5 mgm prednisone. The average person would produce 3-6 mg of pred daily. So why use a substitute? The synthetic has more anti-inflammatory effect; but has less effect ...Read more


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Why does prednisone make you tired?

Why does prednisone make you tired?

Generally not: If anything it can make you feel more energetic. ...Read more

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I feel very tired all the time. I am taking 5mg prednisone daily plus 2x seretide 500. Is tiredness a side effect?

I feel very tired all the time. I am taking 5mg prednisone daily plus 2x seretide 500. Is tiredness a side effect?

Not likely. . .: Seretide is sold in states as serevent (salmeterol), which along w/prednisone, suggests that you have either COPD or asthma. Feeling tired all the time isn't really a side effect of these meds (if anything, it's opposite effect of what's experienced w/prednisone). Therefore you need to go see your family doc (or who prescribed these meds) and tell him/her what you wrote. Perhaps not enough o2. ...Read more

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Why does prednisone cause excessive urination and sugar craving and excess tiredness? I get this every time I take it. Anyway to curb sx?

Why does prednisone cause excessive urination and sugar craving and excess tiredness? I get this every time I take it. Anyway to curb sx?

Different Steroid: Steroids influence many of your bodies functions strongly and broadly. If you are having consistent problems with side effects from the prednisone. Talk to your doctor about other options when you require treatment with steroids. ...Read more

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Can prednisone make you tired?

Can prednisone make you tired?

Yes, but...: Different people have different reactions to prednisone. Prednisone can make a person tired, fussy, excited, irritable, etc... However, many illnesses can make a person tired, so one cannot simply blame tiredness on the Prednisone (the doctor can consider the various causes of the tiredness). ...Read more

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Can coming off prednisone make you tired and weak? Been tapering for 2 weeks. Last dose was Tuesday 5 mg. How long should this last for?

Can coming off prednisone make you tired and weak? Been tapering for 2 weeks. Last dose was Tuesday 5 mg. How long should this last for?

Reevalution: Prednisone is used to treat a variety of conditions. Worsening fatigue as Prednisone is tapered may be a sign that the original condition being treated may be flaring. Ante-evaluation would be in order. ...Read more

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Can prednisone make a person tired?

Yes but why on pred: It depends why you are on prednisone. That may be the reason for your fati gue. Prednisone can interfere with quality sleep and this can cause fatigue. You can discuss your fatigue with your physician. Often daytime fatigue is due to poor quality of sleep and a sleep study may help. ...Read more

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Can prednisone cause someone to become extremely tired out of nowhere?

Yes, talk to doc: High-dose prednisone can cause many side effects. You may get hyper or very tired, euphoric or depressed. When it is stopped, you may feel even more tired.
If you have been on prednisone for many months, your adrenal gland may stop working leading to a transient adrenal failure. Note also that the disease condition for which prednisone is prescribed may be be a factor. Call your doc. ...Read more

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Prednisone is making me tired. Anything I can do to combat this?

Prednisone is making me tired. Anything I can do to combat this?

Yes - one option is: Acupuncture. Kidney (tradtional chinese medicine) can be enhanced to increase overall energy level. Take care. ...Read more

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I feel tired and sad all the time since my diagnosis. Can mtx and prednisone make you feel this way?

I feel tired and sad all the time since my diagnosis. Can mtx and prednisone make you feel this way?

Treatment effect: Yes. Steroids can affect yr psyche and mental well being. Discuss with your doctor. At age 23, you don't need those 2 meds in my opinion. They can have some serious long term effects. ...Read more

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My Dr. Prescribed 20mg Prednisone for bursitis but I'm also noticing body as a whole improvement. No fatigue and suspect it is benefiting adrenals.?

My Dr. Prescribed 20mg Prednisone for bursitis but I'm also noticing body as a whole improvement. No fatigue and suspect it is benefiting adrenals.?

Prednisone feel good: 52 M with HTN notes: My Dr. Prescribed 20mg Prednisone for bursitis but I'm also noticing body as a whole improvement. No fatigue and suspect it is benefiting adrenals.? ANS: No it is increasing your blood levels of cortisol like steroids. A major "side effect" is that it may increase good mood. Can also increase BP, blood sugar, and do many other bad things. But for short time should be OK. ...Read more

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Prescribed Prednisone & Valtrex (valacyclovir) for Shingles. Shgles, so far, seems ro be mild, but Prednisone (10 mg, 1st dose this morning) has made me tired. Normal?

PREDNISONE TIRED?: SOMEHOW, I BELIEVE IT MAY BE THE SHINGLES THAT IS MAKING YOU TIRED!
CHECK WITH THE DOCTOR WHO IS TREATING YOU.
BEST LUCK. . . ...Read more

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Steroids like prednisone. Can it help with severe chronic fatigue?

Steroids like prednisone. Can it help with severe chronic fatigue?

Not generally: Unless you are suffering from addison's disease I would not expect it to. You need to have appropriate lab work like acth and cortisol levels at a minimum which would help in diagnosing your condition. These drugs have severe consequences if used improperly. You need to see a physician. ...Read more

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Is it okay to stop taking prednisone after a dose of 40 mg daily for ten days without tapering, I have fatigue and tinnitus.

Is it okay to stop taking prednisone after a dose of 40 mg daily for ten days without tapering, I have fatigue and tinnitus.

Yes it probly is.: You are very unlikely to develop adrenal insufficency after ten days of taking steroids and from that standpoint you can stop them without tapering. Depending on what the reason was for the steroids to be prescribed in the first place, you may need to taper them however. ...Read more

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Non-fasting blood sugar was 162. Had been on prednisone. Could high blood sugar make someone feel tired a lot? Am not diabetic (yet?)

Non-fasting blood sugar was 162. Had been on prednisone. Could high blood sugar make someone feel tired a lot? Am not diabetic (yet?)

Not the right test: You need to have blood glucose tested after an 8 hour fast. Alternatively you could get an A1c test and either would be more useful in deciding the diagnosis of diabetes. Your tiredness is more likely due to the issue for which you are taking prednisone. ...Read more

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Using plaquenil (hydroxychloroquine) 200 mg twice a day and prednisone 5 mg daily. For rheumatoid im stiff and achy again. Will I need more meds my fatigue is bad too.

Using plaquenil (hydroxychloroquine) 200 mg twice a day and prednisone 5 mg daily. For rheumatoid im stiff and achy again. Will I need more meds my fatigue is bad too.

Yes: If you have swelling or dynovitis you will require something stronger than plaquenil (hydroxychloroquine). The Prednisone should also be tapered. If this cannot be done without increased disease problems you will require stronger medication. ...Read more

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Dizziness, vision blurriness, & confusion that lasts hours or days on/off x 3 yrs. Prednisone clears up sx. MD wants EEG. Worth it? Tired of useless tests

Dizziness, vision blurriness, & confusion that lasts hours or days on/off x 3 yrs. Prednisone clears up sx. MD wants EEG. Worth it? Tired of useless tests

Yes: These symptoms sound like central (brain) disorder. The EEG may give important information. The fact that prednisone helped may indicate an inflammatory disorder. See a neurologist. The fact that the symptoms have been present for 3 years strongly indicates that you should have an MRI of the brain. All these symptoms for such a long time really needs a neurological diagnosis ASAP. ...Read more

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allergy tests done was given Flonase & told come back 1x weekfor shots, night in hospital. My Dr gave me prednisone now very tired? Why?

allergy tests done was given Flonase & told come back 1x weekfor shots, night in hospital. My Dr gave me prednisone now very tired? Why?

Allergic reaction: Hi. I am not sure by your message what the order of things was- but it sounds like you might have had a reaction to allergy testing. It is very rare to have an allergic reaction that requires prednisone after testing alone. Allergy shots help with allergies of the nose, eyes and with allergic asthma. I would follow up with your allergist regarding the reaction that you had. ...Read more

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Would methotrexate be a good choice for my dysautonomia/cfs? Inflamation, fatigue my biggest symp's. Prednisone helps but can't stay on it of course.

Would methotrexate be a good choice for my dysautonomia/cfs? Inflamation, fatigue my biggest symp's. Prednisone helps but can't stay on it of course.

See below: We do not typically use Methotrexate for that and Prednisone is not typically used for that either. You might want to discuss with doctor and/or consider seeking a second opinion. ...Read more

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I am taking 100 mg azathioprine; 25 mg prednisone for Crohn's flare. I have constant headache and fatigue. Side effect?

I am taking 100 mg azathioprine; 25 mg prednisone for Crohn's flare. I have constant headache and fatigue. Side effect?

Non specific symptom: Unfortunately, headache and fatigue are non-specific. You are on relatively high doses of azathioprine and prednisone. The Prednisone is a steroid. Side effects include trouble sleeping, nervousness, heartburn. Azathioprine suppresses immune system. Side effects include nausea, vomiting, poor appetite. The crohn's flare alone can cause fatigue and headache, just like any illness. ...Read more

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I have multiple unexplained bruising on my hip and leg (one side) as well as leg aches and fatigue, on prednisone 20mg a day for a week, is it linked?

I have multiple unexplained bruising on my hip and leg (one side) as well as leg aches and fatigue, on prednisone 20mg a day for a week, is it linked?

Probably related: Prednisone makes the skin and blood vessels fragile, so much more prone to easy bruising with normal daily activity, for example if you sleep on the side where the bruising is. Muscle aches and fatigue can also be related either to the Prednisone itself, or to whatever condition the Prednisone is being used to treat. If the leg is also swollen, see your doctor to be sure it's not a blood clot. ...Read more

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Have either a virus in the ear or menieres disease dr put on 12 days of prednisone is it normal to feel tired and queasy also will it cause moon face?

Not usually: Moon face is not expected after only 12 days of Prednisone unless the dose exceeds 80 mg a day but even then it is unlikely that you will end up with a moon face. However you may gain weight. High dose of Prednisone may also upset the stomach but feeling tired is uncommon. Since high dose of Prednisone may reduce your blood potassium level, consult your doctor re. It. ...Read more

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I have SLE and the last 3 days have had a low body temp of 95.2 to 95.6, nausea. Fatigue, dizzy and weak. Prednisone usage for 22 yrs. What is happening?

I have SLE and the last 3 days have had a low body temp of 95.2 to 95.6, nausea. Fatigue, dizzy and weak. Prednisone usage for 22 yrs. What is happening?

U R asking wrong doc: Why don't you call the doctor who is treating your lupus and speak with that person. Without the ability to examine you and order appropriate lab, it is impossible to answer your question. There are several possible causes. ...Read more

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22 yrs of prednisone treatment for SLE. 3days of nausea, fatigue, weakness, dizziness and low body temp between 95.2 to 95.6. What could it be?

Must consider infect: With the long term steroids even with a low temp we must consider infection. Sometimes this can occur when you get a new Prednisone prescription and the new pills are either ineffective or are not bio equivalent to the previous Prednisone pills you need to see your rheumatologist for an evaluation ...Read more

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Can chronic fatigue syndrome come on suddenly? Like one day I'm fine, the next I wake up and can barely move arms and legs? Would prednisone help cfs?

Can chronic fatigue syndrome come on suddenly? Like one day I'm fine, the next I wake up and can barely move arms and legs? Would prednisone help cfs?

CFS hard to treat: CFS is not well understood, but symptoms do occur suddenly or fluctuate. To fit criteria for CFS symptoms have to be ongoing for 6 mos and have features like memory/focus problems, unrefreshing sleep, sore lymph nodes. Steroids like pred help some, but these drugs can have bad long term effects. There is not a proven treatment or cure. Make sure your doc has ruled out other causes of weakness. ...Read more

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