Top
10
Doctor insights on: Does Porphyria Damage My Liver

Share
Dr. Ronald Krauser
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


3

3
Can an abnormal liver test result be a sign of porphyria?

More common causes: Porphyria can cause abnormal liver tests, but there are far more common causes of liver abnormality, e.g., alcohol. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002188/. ...Read more

4

4
What cause a porphyria attack?

What cause a porphyria attack?

Porphyria results…: From lack of an enzyme in the path for making heme, the oxygen-carrying part of blood. There are many triggers for attacks:alcohol; smoking; drugs (barbiturates, sulfa antibiotics) phenytoin; progesterone; sun exposure; increased iron intake; chronic viral illness (hcv, hiv); stress (illness, emotional/ psycho-logical, physical); dieting/fasting. http://www.porphyriafoundation.com/ for more info. ...Read more

5

5
How is acute porphyria usually treated?

How is acute porphyria usually treated?

Supportive care: Glucose and hematin derivatives can be used to manage the acute attacks. The key to treatment is patient education -- it's a lifetime of learning to avoid the triggers and becoming more familiar with the illness than a physician specialist. ...Read more

6

6
Please help! what is the disease porphyria?

Please help! what is the disease porphyria?

Porphyrias: Porphyria (poor-FEAR-e-uh) refers to a group of disorders that result from a buildup of natural chemicals that produce porphyrin in your body. Porphyrins are essential for the function of hemoglobin — a protein in your red blood cells that links to porphyrin, binds iron, and carries oxygen to your organs and tissue. High levels of porphyrins can cause significant problems. Porphyria mainly affects your nervous system, skin and other organs. The signs and symptoms of porphyria can vary, depending on the specific type and severity. Porphyria is usually inherited — one or both parents pass along an abnormal gene to their child. But in some types of porphyria, environmental factors may trigger the development of symptoms. ...Read more

7

7
What is the definition or description of: porphyria?

What is the definition or description of: porphyria?

Porphyria: The porphyrias are metabolic disorders caused by abnormalities in the synthesis of heme, the portion of hemoglobin which carries the iron inside red blood cells. The manifestations of porphyria vary considerably depending on the mutation involved, ranging from light sensitivity to liver failure to nerve damage to bouts of terrible pain. Special testing is required to make an accurate diagnosis. ...Read more

8

8
What is a workup for porphyria? I highly suspect I suffer from it.

What is a workup for porphyria? I highly suspect I suffer from it.

Fairly rare disorder: Would start with a 24 hr urine collection for porphyrins, and if convincingly positive could do additional studies. However, low level elevations may be seen associated with dietary intake. A hematologist could aid in your assessment. ...Read more

9

9
How are the porphyrias inherited?  can my children inherit porphyria from me?

How are the porphyrias inherited?  can my children inherit porphyria from me?

It is possible: It is autosomal dominant. In addition there are 200 different mutations. The porphobilinogen deaminase gene is responsible - not providing enough to breakdown heme. 1-5 cases per 100, 000 people in the USA. ...Read more

See 1 more doctor answer
10

10
Is porphyria research being conducted?  how can I volunteer to participate in research? 

Porphyria research: Information about ongoing research can be found at the american porphyria foundation website. Www. Porphyriafoundation.Com. ...Read more

See 1 more doctor answer
Dr. Aletha Tippett
89 doctors shared insights

Porphyria (Definition)

The porphyrias are metabolic disorders caused by abnormalities in the synthesis of heme, the portion of hemoglobin which carries the iron inside red blood cells. The manifestations of porphyria vary considerably depending on the mutation involved, ranging from light sensitivity to liver failure to nerve damage to bouts of terrible pain. Special testing is required to ...Read more