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Doctor insights on: Does Pernicious Anemia Run In Families

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Does pernicious anemia run in families?

Does pernicious anemia run in families?

Rarely: Most cases of pernicious anemia are acquired due to immune destruction of the stomach cells which produce intrinsic factor. This results in poor absorption of B12 from food and patients get anemic as a result. Only rarely can children get this as a congenital causes. ...Read more

Pernicious Anemia (Definition)

A decrease in red blood cells when the body can't ...Read more


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Does hashimoto's run in families? And does it have potential to cause pernicious anemia?

Does hashimoto's run in families? And does it have potential to cause pernicious anemia?

Yes! To both!!: Both may be autoimmune diseases and frequently are hereditary! Both are very easily diagnosed by lab tests! See your physician if you think you have either of these illnesses! ...Read more

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I tested positive for ana, and have a family history of lupus and pernicious anemia. What do I do now?

Wait: Many normal people have low-titer positive ana's and they mean nothing by themselves. If you have symptoms suggestive of lupus, continue the workup and consider seeing a rheumatologist. If you have a family history of pernicious anemia, you'd do well to get a serum B12 assay every few years. ...Read more

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B12 level 500 folate level 7, dr prescribed folic acid when previously had b12 injections, is this beneficial?, pernicious anemia runs in the family

B12 level 500 folate level 7, dr prescribed folic acid when previously had b12 injections, is this beneficial?, pernicious anemia runs in the family

Need both: You B12 level is normal while folic acid level is borderline. Please follow your doctor's advice about taking the two vitamins at the recommended intervals.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Is there a specific blood test to diagnose pernicious anemia? I have a family history. My doctor told me I have borderline B12 deficiency.

Is there a specific blood test to diagnose pernicious anemia? I have a family history. My doctor told me I have borderline B12 deficiency.

Pernicious anemia: Yes your doctor can run a battery of tests including a cbc, peripheral blood smear, a serum b 12 level, and a reticulocyte count. These usually will help to diagnose the condition. Sometimes methylmalonic acid and homocysteine levels will be drawn to help with the diagnosis. ...Read more

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Can pernicious anemia be cured?

Can pernicious anemia be cured?

Not usually.: Classical pernicious anemia is caused by auto-antibodies against intrinsic factor-producing parietal cells of the stomach. Treatment is lifelong vitamin B12 administration, which is safer than using immunosuppressive medications that could lead to severe infections. Other kinds of B12 deficiency can possibly cured depending on the cause. ...Read more

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Is pernicious anemia life-shortening?

Is pernicious anemia life-shortening?

Should not be!: It did shorten lives. But with B12, there should be no shortening of life!!!!!!!!!!!!!!!!!!! ...Read more

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Could pernicious anemia shorten life?

Probably no: If you have pernicious anemia you do not absorb B12 effectively. That is easily fixed with either B12 injections or large B12 oral doses daily. Unfortunately, patients with B12 deficiency often have other associated autoimmune issues that develop. In general though, pa alone will not shorten life as long as you treat it correctly. ...Read more

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What are the symptoms for pernicious anemia?

Fatigue: Caused by an anemia with large red blood cells! Reversible quickly with B12! ...Read more

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What are the causes of symptoms in pernicious anemia?

What are the causes of symptoms in pernicious anemia?

Lack of vitamin B12: Pernicious anemia is due to a lack of vitamin b12. B12 is necessary for the normal function of the nervous system and the formation of red blood cells. ...Read more

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How to treat pernicious anemia?

How to treat pernicious anemia?

B-12 deficiency: Unless there is an intestinal parasite, we usually just do blood studies to confirm and supplement vitamin b-12 using 1000 mcg injected monthly, i.M. Some pts will absorb sufficient amounts by mouth or intranasal routes, but most efficient to inject. ...Read more

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Is there a cure for pernicious anemia?

Is there a cure for pernicious anemia?

Treatable: This condition can be well treated with life-long use of B12 injections or nasal sprays and results in normalisation of the blood counts. ...Read more

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Does methadone cause pernicious anemia?

Does methadone cause pernicious anemia?

Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them.

Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more

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Is methadone a cause of pernicious anemia?

No: Unaware of any association. True pernicious anemia is an autoimmune disease, caused by antibodies to the cells in our stomachs that produce intrinsic factor, which is needed to absorb vitamin B12 from our intestines. It may be hereditary or acquired. There are other causes of B12 deficiency, including stomach and intestinal diseases/surgery, and lack of B12 in diet. A hematologist can help. ...Read more

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I have pernicious anemia - must I give up alcohol?

I have pernicious anemia - must I give up alcohol?

Certainly: Pernicious anemia is due to vitamin B12 deficiency. Alcohol in many ways can contribute to B12 deficiency: 1. Interferes with b vitamin absorption - alcoholics also do not have enough b vitamins in their diet 2. May cause gastritis leading to poor acid secretion in stomach (acid helps B12 absorption) 3. May cause intestinal damage leading to malabsorption. Thus, better to avoid alcohol! ...Read more

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Does your personality change with pernicious anemia?

It can: Pernicious anemia (a severe type of vitamin B12 deficiency) can cause memory problems, irritability, and dementia. Dementia goes beyond having memory problems, and can include difficulties with understanding, reasoning, handling multi-step tasks, and can be accompanied by personality changes. Symptoms generally improve with treatment. ...Read more

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How does pernicious anemia cause people to have achlorhydria?

The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read more

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Is it true that leukemia and pernicious anemia the same thing?

Not at all: Pernicious anemia results from poor dietary uptake of vitamin b12, usually from a loss of certain cells in your stomach. These cells secrete intrinsic factor, necessary for absorption of vitamin b12. Treatment is B12 shots, potentially. Leukemia is cancer. Treatment is chemotherapy. ...Read more

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What's the difference between pernicious anemia and B12 anemia?

What's the difference between pernicious anemia and B12 anemia?

See below: B-12 anemia is a deficiency in vitamin b-12 (cobalamin). Pernicious anemia is a deficiency or lack in intrinsic factor (produced by cells in the stomach) which is a protein essential for absorption of vitamin B12 in the ileum (small intestine). Pernicious anemia requires replacement of intrinsic factor &/or b-12. B-12 anemia needs only b-12 supplementation. ...Read more

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What will happen to people who have pernicious anemia but are intolerant to b12?

Bad blood and nerves: B 12 is a vitamin that essential for life.
B12 deficiency if goes untreated can lead to severe anemia and neuropathy, not to mention dementia.
try another formulation of B12 ...Read more

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What are the markers for pernicious anemia and what are some grey areas or areas to watch?

What are the markers for pernicious anemia and what are some grey areas or areas to watch?

It is easy to Diagno: Pernicious anemia is caused by Vitamin B12 deficiency. Therefore a Blood test can measure the B12 level in the blood and give you/your doctor the answer to your question. It is usually associated with larger sized red cells (Macrocytic Anemia) and bone marrow shows megaloblasts. ...Read more

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Please explain what happens to people who have pernicious anemia but are intolerant to b12?

Please explain what happens to people who have pernicious anemia but are intolerant to b12?

Can you clarify?: If you have pernicious anemia and aren't effectively treated, you will first lose your mind and then your life. If by "B12 intolerance" you simply mean you cannot absorb the vitamin orally, this is common and you'll need monthly injections. If you believe that the supplement makes you sick -- as it claimed on some "pop" websites -- I'm skeptical but you'll need to get specialist consultation. ...Read more

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I'm curious what could happen to people who have pernicious anemia but are intolerant to b12?

Vit b12: If you have pernicious anemia- and you do not take replacement of vit B12- your vitamin b12 obviously will continue to go down. Anemia, weakness, fatigue, memory problem, forgetfulness, neuropathy, dementia can happen with significant vitamin b12 deficiency- and those can become permanent if you do not take supplement of vit b12. what do you mean by intolerance? You can get via IM, sublingual. ...Read more

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Can 7yrs of undiagnosed coeliacs cause pernicious anemia, irreversible villi damage and miscarriages?

Gi issues: This is a question best answered by a gastro intestinal specialist, I would seek a consult to find this answer. ...Read more

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Husband has gout and pernicious anemia. What kind of diet should he be on and what sort of care should he be given?

Husband has gout and pernicious anemia. What kind of diet should he be on and what sort of care should he be given?

Gout diet: B12 injections ongoing. Take in tart cherry juice +tart cherries, 10/day. Add Lemon extract 2 tblspns/day. Avoid alcohol, animal fats, organ meats, anchovies, sardines, tuna, salmon, and shellfish. Limit other meats to 4 oz/day. Avoid high fructose corn syrup containing drinks and foods. Add egg whites, quinoa, soy as protein. Eat lots of citrus fruit and veggies. Drink 3 L /day. Multivit ...Read more

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My sister was diagnosed with paroxymal hemaglobinuia and pernicious anemia can she live long with this she is 46?

PNH can have: A wide spectrum of severity. Treatments are available and prognosis is pretty good. It would be unusual to have pernicious anemia as well. Are you sure she has both? ...Read more

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What are the causes of pernicious anemia and what are the treatments for it?

Classical: Pernicious anemia (b12 deficiency) occurs when a cofactor in the stomach, intrinsic factor, does not do its job. If is needed for B12 absorption. ...Read more

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Is pernicious anemia helped by B12 vitamins as well as as B12 injections?

Most true B-12: Deficiencies are due to loss of "intrinsic factor", secreted by the stomach, it aids absorption, so if it is missing pills will not work. Shots of b-12, cyanocobalamine, are bright red, and are used for placebo effect in some instances. Most people have intrinsic factor, normal b-12 levels. ...Read more

Dr. Steven Ginsberg
1,283 Doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more