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Doctor insights on: Does Nsaid Use Cause Urticaria

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Using Otc Pain Meds (Definition)

Over-the-counter pain relievers Pain relievers like acetaminophen (Tylenol) and aspirin are familiar choices for the treatment of osteoarthritis. * Acetaminophen generally is considered safe, although it may pose risks to some individuals with liver disease or when taken in excessive doses. * Aspirin is a popular medicine for many arthritic disorders because of its ability to relieve pain as well as inflammation (swelling, redness). However, aspirin is not suitable for people who have had a stomach ulcer or aspirin allergy. Nonsteroidal anti-inflammatory drugs (NSAIDs) NSAIDS relieve pain as well as inflammation. There are a wide variety of NSAIDs to choose from. Over-the-counter forms include: * Ibuprofen (Advil, ...Read more


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Confused about nsaids.They r a common cause of chronic hives. Does this mean the person is allergic to nsaids, or just that hives r a common side efct?

NSAIDs: Unlike allergic reactions to pollens, animal dander and foods, in which there are allergic antibodies (ige) against the trigger, reactions to Aspirin and other nsaids generally do not occur as a result of ige. Therefore, allergy testing is not usually of benefit. In some cases, an oral challenge may be performed under the supervision of an allergist to evaluate for sensitivity or tolerance. ...Read more

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My wife has RA and ALL NSAIDS cause Hives whenever she take any.And despite the chronic hives.If she insist on taking them. Will she suffer any harm?

My wife has RA and ALL NSAIDS cause Hives whenever she take any.And despite the chronic hives.If she insist on taking them. Will she suffer any harm?

Stop them: NSAIDs are a poor choice to treat RA. Continued use by a person who is allergic to them may lead to more serious and even life threatening allergic reactions. I hope she is under the care of a rheumatologist. ...Read more

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If a person pre-medicates w/xyzal & zantac, (ranitidine) can they take an nsaid drug, if that drug has caused minor hives in the past? Get skin reaction only.

If a person pre-medicates w/xyzal & zantac, (ranitidine) can they take an nsaid drug, if that drug has caused minor hives in the past? Get skin reaction only.

Possibly: Both xyzal (levocetirizine) & zantac have anti-histamine effects & may decrease or eliminate a mild reaction to nsaid. However, this can be dangerous. Repeat exposures to something you are allergic to can be more severe, including breathing & swallowing difficulties, swelling of the face, lips, tongue or mouth. 6 classes of nsaids exist; you may not be allergic to other NSAID classes. An allergist may help a lot. ...Read more

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I seem to get a hive or two an hr or so after taking any meds. Hives from xyzal, benadryl, (diphenhydramine) mestinon, nsaids, and others. Why does any pill cause hives?

I seem to get a hive or two an hr or so after taking any meds. Hives from xyzal, benadryl, (diphenhydramine) mestinon, nsaids, and others. Why does any pill cause hives?

Doubtful: It is highly unlikely that anyone can be allergic to all medications with different chemical structure. The only common denominator may be from the gelatin capsule which people may be allergic . But all bets are off if you have the same problem with tablets. Suggest you consult an allergist and undergo some challenge test else you may have trouble getting emergency care. ...Read more

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If i premedicate w/xyzal, zantac, (ranitidine) can I start using nsaids again, even tho they caused minor hives in the past? Allergist says yes, but i'm nervous.

If i premedicate w/xyzal, zantac, (ranitidine) can I start using nsaids again, even tho they caused minor hives in the past? Allergist says yes, but i'm nervous.

No: This is not correct, and i would not do it at home, if you need to take nsaids , you need to be desensitized under strict protocols and in a medical setting, not in an office setting. ...Read more

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I get hives from ibuprofen. Does that mean every type of nsaid causes me hives, or is this a one-specific drug situation usually? Would Aleve (naproxen) be ok?

No: Aleve (naproxen) is not okay. They is a higher probability you are allergic to that med as well as it is the same basic compound as ibuprofen. You can try another NSAID but these are all prescription meds. ...Read more

Dr. Corey Clay
3 doctors shared insights

Hives (Definition)

Also known as urticaria, hives are an outbreak of red bumps or wheals that appear quickly after exposure to certain allergens (foods, medications, other substances). Hives vary in size, are itchy, can burn, and can last for up to ...Read more


Nsaids (Definition)

Nsaid stands for non steroidal anti inflammatory agent. So the most potent anti inflammatory agents are steroids like prednisone. Nsaids are ...Read more