Doctor insights on:
Does Methotrexate Work Well To Help With Psoriasis
An autoimmune disease involving the skin, nails, and occasionally the joints. It is not contagious. There are several types of skin lesions, most common variety being large red scaly itchy plaques on extensor surfaces such as elbows and knees. Psoriasis can be controlled by a wide variety of medications, but a cure has ...Read more
Psoriasis+psor. Arthritis..Methotrexate 15mg for 2 mos. Already+humira weekly..Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe..Ok?
Humira and Methotrexate are not working for my psoriasis. I asked the doctor about Stelara (ustekinumab). Dr. hasn't seen good results w/other patients on Stelera so doesn't use it. What would you recommend?
STELERA/HUMIRA/METHT: Well if you have no improvement with Humira (adalimumab) and methtrexate, than there is no harm in trying stelera.Discuss with your doctor that it is not working, so what is the harm in trying if stelera will work for you otherwise you can get a second opinion from another dermatologist. ...Read moreSee 3 more doctor answers
Yes. Agree, but....: Methotrexate can be very effective. However, the first studies raising the specter of liver disease came from psoriasis patients on daily low dose oral mtx!. The first pass effect is dangerous for the liver. Mtx cannot be adjudicated aqs an oral drug. Absorption is variable (40-90%), causes GI upset, and hits the liver first. I only use subcutaneous mtx once weekly. This is the safest! ...Read moreSee 1 more doctor answer
I am on methotrexate for severe psoriasis.Can I come off it as I have read of serious side effects.Thanks?
My Dr. wants me back on methotrexate b/c of inflammation levels in my body. Whats your opinion on inflammation in the body & psoriasis?
My age is 29yrs. For psoriasis, i'm taking methotrexate 7.5 mg since 7yrs. Using this, what are the side effects to me in long term.Plz suggest?
I was taking methotrexate a year for psoriasis & it helped a ton. When I stopped taking it my psoriasis went into overdrive & little spots all over?
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
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