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Doctor insights on: Does Magnesium Help Reestablish Adderall Tolerance

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I've heard that a magnesium and potassium supplement can help with Adderall (dextroamphetamine and racemic amphetamine) tolerance. Is that true?

I've heard that a magnesium and potassium supplement can help with Adderall (dextroamphetamine and racemic amphetamine) tolerance. Is that true?

See answer: Some users of Adderall (dextroamphetamine and racemic amphetamine) suggest that taking magnesium and potassium supplements along with the medication helps to reduce tolerance. However, I am unaware of any validated or reproducible authoritarian sources or scientific research that support these claims. There is some research suggesting that magnesium supplementation might help to improve ADHD type symptoms in children with the disorder. ...Read more

Tolerance (Definition)

When one takes a drug, such as heroin or alcohol, repeatedly, 'tolerance' develops because more of the drug is needed to give the same effect on the body/brain; e.g. Liver enzymes r stimulated to metabolize the drug faster and faster. There may be a strong genetic predisposition to addiction, some studies suggesting that 1 of 10 people will become dependent on alcohol or some ...Read more


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What kind of magnesium to take with adderall (dextroamphetamine and racemic amphetamine)?

What kind of magnesium to take with adderall (dextroamphetamine and racemic amphetamine)?

Avoid Magnesium: It potentiates (aggravates) the side effects and can cause restlessness, tremor, rapid breathing, confusion, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures.

DO NOT TAKE MAGNESIUM WITH ADDERALL (dextroamphetamine and racemic amphetamine) ...Read more

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Hello - I take Adderall and Vyvanse (lisdexamfetamine) daily. May I take a magnesium oxide/zinc sulfate/calcium carbonate supplement?

Yes you may: You should be just fine taking your supplements, but please consider taking them at night. This would help prevent any changes in the absorption of your ADHD medications. ...Read more

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Can adderal cause low potassium and magnesium levels?

Can adderal cause low potassium and magnesium levels?

Not usually: Adderall (dextroamphetamine and racemic amphetamine) does not usually affect electrolyte levels on its own. Use of diuretics could, though. ...Read more

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Would caffeine increase Adderall tolerance? Since have grant similar effects?

Would caffeine increase Adderall tolerance? Since have grant similar effects?

Both stimulants: Caffiene and psycho stimulants have similar effects raising heart rate/blood pressure, helping people feel more focused but potentially interfering with sleep. Psychostimulants are prescribed to treat attention deficit disorder with or without hyperactivity. Caffeine + meds are additive. Too much can make people feel irritable, agitated with GI upset (nausea). See how it affects you. ...Read more

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Will taking Adderall affect my Modafinil tolerance? (and vice versa?)Since both drugs have the same effects (keeping you awake)

Probably: Since both medications act in similar fashion, tolerance for one may mirror tolerance for the other. Your pharmacist can advise you best about your medications, however. ...Read more

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I've been on Adderall 20mg XR for a week. The last two days it didn't feel as effective. Has my body already built up a tolerance to it that quickly?

I've been on Adderall 20mg XR for a week. The last two days it didn't feel as effective. Has my body already built up a tolerance to it that quickly?

Not necessarily: I find that sometimes when titrating up a patient's dose on a stimulant, they may intially have a more robust response when the dose is first increasd, and then it may drop a little. ...Read more

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How to approach Dr. That my Adderall tolerance has gone up? Been on 60mg daily for 9.5 yrs. Vyvanse (lisdexamfetamine) only one compareable and doesn't work!

That's a pretty high: Dose. Talk to your doctor about possibly adding a non-stimulant medication as an adjunct. (S)he may need to make changes in your other psychotropic medications, depending on which non-stimulant is selected. Document the onset & duration of action of your current meds & how/when breakthrough ADHD symptoms impact your daily functioning. Just give your doctor the facts. ...Read more

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Can Zoloft (sertraline) decrease the effects of adderall? Or could I be gaining a tolerance to adderall?

Agree w Dr. Pappas.: Per Drugs. Com drug interaction checker - drug interaction checker > Adderall (amphetamine / dextroamphetamine) plus Zoloft (sertraline) may ^ risk for serotonergic syndrome. May also ^ side effects of nervousness, anxiety, racing thoughts and restlessness. However, it is usually safe together. ...Read more

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Is it possible to build up a tolerance to adderall (dextroamphetamine and racemic amphetamine)?

Is it possible to build up a tolerance to adderall (dextroamphetamine and racemic amphetamine)?

Potentially yes.: That is possible. Please let your prescribing physician know if you suspect that may be happening. ...Read more

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Does a person's tolerance to Adderall (dextroamphetamine and racemic amphetamine) ever change?

Tolerance changes: Through the life cycle, our physiology changes. Our ability to digest and absorb nutrients and drugs changes with aging. Our constitutional ability to adapt, while not well studied, is also known to change relative to our life style.
So does the tolerability of any drug change over time? Not necessarily, but most certainly it could. ...Read more

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I was on Ritalin 120mg day, developed tolerance. Now Adderall 120mg, but unhelpful & side effects. Would Focalin (dexmethylphenidate) be better? & what dose comparable?

I was on Ritalin 120mg day, developed tolerance. Now Adderall 120mg, but unhelpful & side effects. Would Focalin (dexmethylphenidate) be better? & what dose comparable?

See below: Focalin (dexmethylphenidate) XR might feel better than Ritalin for some with ADHD. But tolerance to a medication typically requires being off. Dosing is best left to the psychiatrist who can evaluate you as it will also need to include weighing tolerance, symptoms and side effects. ...Read more

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What to do if I have a big tolerance to Adderall (dextroamphetamine and racemic amphetamine) and have to take up to like 80. to 100 mgs to feel the benefits of it.?

Adderall (dextroamphetamine and racemic amphetamine): The maximum FDA recommended dose of Adderall (dextroamphetamine and racemic amphetamine) is 60 mg daily. Taking a higher dose of a medication, if not prescribed by your doctor, is not only dangerous but basically illegal since this is a highly controlled medication. It is a sign of tolerance and could mean you are at risk of addiction. See your doctor for assistance and be careful. ...Read more

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Looking for ways to fix a tolerance to adderall (dextroamphetamine and racemic amphetamine). only have been taking it for 5 days and it no longer has an effect on me. Suggestions for this please?

Needs follow up...: You need to discuss this with your prescriber and see if you need a higher dose. 5 days might be too early to determine if the medication really works or not. I would wait and give it more time and then follow up as needed with your doctor on this. ...Read more

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Is consumption of 20 mg Adderall (dextroamphetamine and racemic amphetamine) in every two weeks enough to build tolerance?

Unlikely: Taking a 20 mg dose of Adderall (dextroamphetamine and racemic amphetamine) every 2 weeks is unlikely to cause tolerance. ...Read more

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Have you seen tolerance from taking Adderall (dextroamphetamine and racemic amphetamine) for several years? Should I take drug holiday?

Tolerance adderall (dextroamphetamine and racemic amphetamine): Yes it happens quite often and you have to increase the dose. You may try a drug hliday if you can function without Adderall (dextroamphetamine and racemic amphetamine) for few weeks, or get an increase in the dose, or try a different drug in the same category
these are the choices, discuss with your doctor. ...Read more

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Is 90 mg of Adderall (dextroamphetamine and racemic amphetamine) a fatal amount for a 215 lbs adult male with a medium-high tolerance? (Not taking this amount, was just asked this question)

Depends on person.: According to FDA "Individual patient response to amphetamines varies widely. While toxic symptoms occasionally occur as an idiosyncrasy at doses as low as 2 mg, they are rare with doses of less than 15 mg; 30 mg can produce severe reactions, yet doses of 400 to 500 mg are not necessarily fatal." Safest thing to do is follow your doctor's prescription for you, and don't experiment. ...Read more

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I've built up tolerance to my prescribed 60mg daily of Adderall (dextroamphetamine and racemic amphetamine) XR and I'm a little worried. Should I ask the doc to increase or continue w/ this dose?

Already above max: It is not unusually higher, but your 60mg is already more than the recommended 40mg/day for adults. Paradoxically, iIt's possible that you could even do better on a lower dose. Read this and ask your provider (psychiatrist, I hope): http://www. Healthboards. Com/boards/4025373-post4.html
Please do not just ask a PCP to increase over recommended doses. It's not fair to either of you. Best! ...Read more

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If I'm tolerant to amphetamines like adderall in adhd treatment would the tolerance cross over to ritalin (methylphenidate) if I switched?

If I'm tolerant to amphetamines like adderall in adhd treatment would the tolerance cross over to ritalin (methylphenidate) if I switched?

Tolerance likely: You say you're "tolerant" to amphetamines rather than they're not helping your ADHD. That is a word most ADD/ADHD patients don't use in my experience. If you mean you're not feeling a buzz or more pleasant mood effect from amphetamines, I would recommend avoiding any medication including Ritalin (methylphenidate) which is potentially addictive. There are other meds for ADHD which are safer for you. ...Read more

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I've been taking 20mg of Adderall (dextroamphetamine and racemic amphetamine) daily for 6 months and I've developed a tolerance. I've heard it causes a permenant down regulation of dopamine receptors. Will they ever getback to normal?

I've been taking 20mg of Adderall (dextroamphetamine and racemic amphetamine) daily for 6 months and I've developed a tolerance. I've heard it causes a permenant down regulation of dopamine receptors. Will they ever getback to normal?

Adderall (dextroamphetamine and racemic amphetamine): You can wean yourself off Adderall (dextroamphetamine and racemic amphetamine) with regaining full sensitivity to it eventually. You cannot stop it "cold turkey", though, to avoid withdrawal. The weaning process must be gradual and under the supervision of a physician. ...Read more

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I have seen that nootropics have been used to combat Adderall (dextroamphetamine and racemic amphetamine) tolerance, (memantine - namenda) looking on the internet. Holiday not an option?

Holiday maybe: What is Adderall intolerance for you? Do you mean intolerable adverse effects? If so you should discuss other treatment options with your doctor. Namenda (memantine) is marginal at best for adhd, & is more helpful for people with learning disabilities. You may have unrecognized/untreated comorbid conditions such as depression, anxiety, ocd, or learning disabilities that are complicating treatment tolerance. ...Read more

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Is l-tyrosine like Adderall (dextroamphetamine and racemic amphetamine) at all?

Is l-tyrosine like Adderall (dextroamphetamine and racemic amphetamine) at all?

No: L-tyrosine is an Amino Acid which the body uses to build proteins. Adderall (dextroamphetamine and racemic amphetamine) is an amphetamine salt. It's a stimulant. ...Read more

Dr. William Singer
734 Doctors shared insights

Dextroamphetamine And Racemic Amphetamine (Definition)

Dextroamphetamine|racemic amphetamine is an appetite suppressant which is a kind ...Read more


Dr. Alan Ali
853 Doctors shared insights

Adderall (Definition)

Adderall is an appetite suppressant which is a kind ...Read more