Doctor insights on:
Does Macrosomia Cause Congenital Abnormalities
Yes: Uncontrolled diabetes in the first trimester can cause birth defects in the baby, typically heart or skeletal defects. Gestational diabetes acquired later in pregnancy is typically not associated with fetal deformities, but can also cause problems such as a big baby or problems with the amniotic fluid. ...Read moreSee 1 more doctor answer
Congenital malformation is aphysical defect present in a baby at birth that can involve many different parts of the body, including the brain, heart, lungs, liver, bones, and intestinal tract. Congenital malformation can be genetic, it can result from exposure of the fetus to a malforming agent (such as alcohol), or it can ...Read more
They can/some don't: Congenital heart defects include a number of conditions that vary greatly in their impact on final growth. The more severe the defect, the more likely it will require multiple surgeries and impair the bodies strength & growth. The cyanotic or blue baby group of defects are more likely to do this.Some defects, like the common small VSD self correct & seldom if ever alter the patients life. ...Read moreSee 1 more doctor answer
Marfan is caused by : A mutation in the fibrillin gene on the long arm of chromosome 15 , 15q15-q21.3. Autisomal dominant inheritance with widely variable clinical findings. Aneuploidy is having an abnormal # of chromosomes from a genetic accident during cell reduction (meiosis). ...Read moreSee 1 more doctor answer
A few things: Often genetic abnormalities arise spontaneously. Some are due to genetic problems that are passed down in family lines. Some are due to the way the chromosomes from sperm and egg meet and form in an embryo. Lastly, some can be due to exposure radiation which can damage genes. If you're worried that your fetus might have abnormality, you can discuss with geneticist to understand risks. ...Read moreSee 1 more doctor answer
2--3%, up to 7%: The usual quoted rate is as low as 2-3%. However in one prospective study of the outcome of 5, 964 pregnancies the incidence rose to 7%! the cause of 40-60% of congenital anomalies in humans is unknown. These are referred to as sporadic, a term that implies an unknown cause, random occurrence regardless of maternal living conditions. ...Read moreSee 1 more doctor answer
Metabolism: Diabetes is not a simple disease. It wrecks energy metabollism and has an effect on all our cells. During pregnancy this can affect the fetus since mom feeds baby and the excess sugar has its effect in both mom and baby. That is why good control is essential. ...Read moreSee 1 more doctor answer
Controversial: But the overall tide of opinion is that the answer is "no." there was laboratory evidence that lsd could cause damage to germ cells - sperm and eggs - even long after it's ingestion. However, studies of this have not yielded consistent results. There are no human studies, and the vast majority of lsd users (esp in pregnancy) use other substances as well. Avoiding any drugs in pregnancy is best. ...Read more
Besides Diabetes: The answer to your question is yes. ...Read more
Gene errors: We all carry recessive genes to a few conditions that are not a problem unless they come together with another carrier.The closer you are related, the more genes you have in common. Two carriers, can conceive a baby that has both bad recessive genes, with any pregnancy.Whether this produces a fatal metabolic disorder or some lesser problem, the results are the same. The genes define you. ...Read moreSee 1 more doctor answer
No: The short answer is no. Cardiac valve dysfunction does not cause swelling of the axilla. Lymphatic problems can cause swelling. Lymphatic structures do have valves. Lymphedema of the upper extremities is a separate entity altogether and results from medical conditions, can be iatrogenic, or can follow radiation or surgical node dissection. See a lymphedema expert. ...Read more
Hard question: This depends on who is evaluating. It is highly unusual for an important congenital heart defect to be missed by a pediatric cardiologist. A major diagnostic tool for the diagnosis of congenital heart disease is a careful, focused physical examination. Echocardiography under the direction of a pediatric cardiologist is an important, reliable tool to confirm the diagnosis and establish details. ...Read more
AVM Symptoms: Typically, yes. Those symptoms are flank or back pain and bloody urine. A common physical finding is high blood pressure. The caveat here is that these symptoms can also be seen in a wide variety of other renal conditions. Thus, if you are concerned that you may have an avm, please see your doctor for a more thorough evaluation. ...Read more
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