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Doctor insights on: Does Long Term Methadone Use Affect Your Liver

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Does long term methadone use affect your liver?

Does long term methadone use affect your liver?

Probably not: Liver dysfunction is not listed as a serious or less serious effect of Methadone use. One should always be careful with long term use of medications and have routine follow up and lab studies. Many medications used with Methadone certainly could cause liver dysfunction. Methadone is a very serious medication. Take its use and follow up very seriously. ...Read more

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Dr. Harinder Gill
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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I have liver cancer took one dose of 4mg methadone @6am how long till I can take 60 mg OxyContin I am discontinuing methadone ?

I have liver cancer took one dose of 4mg methadone @6am how long till I can take 60 mg OxyContin I am discontinuing methadone ?

Sorry to hear...: For cancer-related pain management, the dose and frequency of taking pain medication should be individualized according to the effectiveness of pain relief and the level of sedation, which may pose its pertinent risk to fall or self-injury. In general, try take it every 4-6 hrs, watch, and see. If something unexpected and undesirable emerges, go to urgent care timely. ...Read more

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Does methadone effect your liver?

Does methadone effect your liver?

Methadone: Methadone requires liver enzymes to be metabolized and then ultimately eliminated. So one could argue that it may affect the liver. ...Read more

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My whole body is sore itake methadone could that be my problem or could it be my liver from hept c?

My whole body is sore itake methadone could that be my problem or could it be my liver from hept c?

Hepatitis C and pain: Hep c can cause joint and muscle pain. Methadone is used for pain treatment and for opioid addiction. Methadone treatment is generally not associated with muscle pain. It could be if you have skipped dosing and have withdrawal or if after long term use you develop opioid induced hyperalgesia, which is a condition where the opioid pain medication (in this case methadone) actually causes more pain. ...Read more

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Can i drive a car with a methadone pump installed in my abdomen? Will it impair my driving?

Can i drive a car with a methadone pump installed in my abdomen? Will it impair my driving?

I : I do not believe it will, however you should verify this with the medical provider who will be placing the pump. All the best. ...Read more

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What are the long term segative side effects of methadone?

What are the long term segative side effects of methadone?

Many: I personally do not use Methadone as i feel the dangers outweigh any advantage over other opioids. The most significant side effects are that of breathing suppression and heart electrical conduction problems. There are drugs such as suboxone (buprenorphine) for the problem of dependence which are much safer and more effective in my opinion. ...Read more

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What are the long term side effects of methadone? What about suboxone?

Some good ones: Methadone can lead to sudden cardiac death at high doses, half life is not as predictable, can have many drug-drug interactions. Suboxone is considered safer. If doing a risk-to-benefit analysis & the choices are staying on illicits or suboxone, the latter wins. Side effects are outweighed by its benefits in many individuals. The 10 year experience in usa limits the answer to 10 years. ...Read more

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I know the text book answer is NO , BUT if I take methadone in the early morning & take Ritalin (methylphenidate) in the afternoon (not long term) , would ritalin (methylphenidate) work?

May be: In theory the two drugs don't interact, as they have opposite effects, not additive effects, methadone has a long half-life, it stays in the system longer, at least 16 hours, its elimination depends on many factors, how active is the liver, how acidic is the urine for example or alkaline, etc.. Also depends on other medicines you are on, counsel your doctor again, both are schedule II medications, ...Read more

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What are the long term effects of methadone use. 10+ years or more. Can it cause dementia?

NO: Methadone can be associated with a number of side effects, but actually very few long-term "organ" effects (heart, liver, kidney, brain etc.) constipation, increased sweating, hormonal changes that alter libido, erectile function and fertility. Weight gain with its attendant problems certainly can occur. Heart rhythm problems, although getting publicity, are rare. Think about alcohol;tobacco use. ...Read more

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What are the long term side effects to being born addicted to methadone?

None for sure: This question has been studied for 50 years. So far no long term effects have been shown. Babies are not born "addicted" to Methadone they are Methadone dependent and have to be weaned off of this opioid as they would any other. At the present time treatment with Methadone during pregnancy is preferable to suboxone primarily because Methadone has a longer history of use without long term effects. ...Read more

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Can you tell me the long term side effects of being born addicted to methadone?

Methadone and Infant: This is a question that is best discussed with your neonatologist/high risk obstetrician and you if you are pregnant or thinking of becoming pregnant and are taking methadone. ...Read more

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Does long term methadone maintenance cause male infertility? My boyfriend has been on MMT for 8 years and we want kids in the future.

It could: long term use of methadone is associated with low testosterone. hopefully he can wean in the future. you can get a sperm count. he can get a testosterone level. also be aware of possible tooth decay from opiates. good luck. ...Read more

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If I stop my long term methadone addiction will my testosterone levels bbegin to increase?

If I stop my long term methadone addiction will my testosterone levels bbegin to increase?

Most likely IF: that is what was causing it. To quibble about semantics, it is PHYSICAL DEPENDENCY on methadone, NOT addiction, unless you were obtaining it without prescription, taking it to get high, and it was destroying your life (like the opioid you were using before you went on methadone). Ditto with pain treatment. Very long-term use of opioids can cause permanent changes, but usually goes back to normal ...Read more

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I have lost nearly all my body hair & most on head due to low t while taking methadone long term. Will the hair grow back with t treatment ?

I have lost nearly all my body hair & most on head due to low t while taking methadone long term. Will the hair grow back with t treatment ?

Hopefully: Hopefully yes. It sounds like you have alopecia univeralis which is a severe form of alopecia areata. This is an autoimmune disease in which your immune system tells your hair follicles to stop growing hair. ...Read more

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Is my long term methadone addiction responsible for my very low testosterone level of just over 100?

Is my long term methadone addiction responsible for my very low testosterone level of just over 100?

See below: It certainly contributed significantly if not completely to the issue. Of course, the low testosterone contributes to depression, fatigue, diabetic tendencies, increased pain, poor cognition, bone weakness to name a few ...Read more

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Dr. Stuart Wasser
645 doctors shared insights

Methadone (Definition)

Methadone is a synthetic opiate used for pain control and in the rehabilitation of opiate addicts. Methadone used in rehabilitation relieves craving, suppresses withdrawal symptoms, and blocks the euphoric effects associated with ...Read more