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Doctor insights on: Does Long Term Methadone Use Affect Your Liver

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Does long term methadone use affect your liver?

Does long term methadone use affect your liver?

Probably not: Liver dysfunction is not listed as a serious or less serious effect of Methadone use. One should always be careful with long term use of medications and have routine follow up and lab studies. Many medications used with Methadone certainly could cause liver dysfunction. Methadone is a very serious medication. Take its use and follow up very seriously. ...Read more

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Dr. Jeffrey Satinover
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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Does methadone effect your liver?

Does methadone effect your liver?

Methadone: Methadone requires liver enzymes to be metabolized and then ultimately eliminated. So one could argue that it may affect the liver. ...Read more

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My whole body is sore itake methadone could that be my problem or could it be my liver from hept c?

My whole body is sore itake methadone could that be my problem or could it be my liver from hept c?

Hepatitis C and pain: Hep c can cause joint and muscle pain. Methadone is used for pain treatment and for opioid addiction. Methadone treatment is generally not associated with muscle pain. It could be if you have skipped dosing and have withdrawal or if after long term use you develop opioid induced hyperalgesia, which is a condition where the opioid pain medication (in this case methadone) actually causes more pain. ...Read more

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What are the long term segative side effects of methadone?

What are the long term segative side effects of methadone?

Many: I personally do not use Methadone as i feel the dangers outweigh any advantage over other opioids. The most significant side effects are that of breathing suppression and heart electrical conduction problems. There are drugs such as suboxone (buprenorphine) for the problem of dependence which are much safer and more effective in my opinion. ...Read more

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What are the long term side effects of methadone? What about suboxone?

Some good ones: Methadone can lead to sudden cardiac death at high doses, half life is not as predictable, can have many drug-drug interactions. Suboxone is considered safer. If doing a risk-to-benefit analysis & the choices are staying on illicits or suboxone, the latter wins. Side effects are outweighed by its benefits in many individuals. The 10 year experience in usa limits the answer to 10 years. ...Read more

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I know the text book answer is NO , BUT if I take methadone in the early morning & take Ritalin (methylphenidate) in the afternoon (not long term) , would ritalin (methylphenidate) work?

May be: In theory the two drugs don't interact, as they have opposite effects, not additive effects, methadone has a long half-life, it stays in the system longer, at least 16 hours, its elimination depends on many factors, how active is the liver, how acidic is the urine for example or alkaline, etc.. Also depends on other medicines you are on, counsel your doctor again, both are schedule II medications, ...Read more

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What are the long term side effects to being born addicted to methadone?

None for sure: This question has been studied for 50 years. So far no long term effects have been shown. Babies are not born "addicted" to Methadone they are Methadone dependent and have to be weaned off of this opioid as they would any other. At the present time treatment with Methadone during pregnancy is preferable to suboxone primarily because Methadone has a longer history of use without long term effects. ...Read more

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Can you tell me the long term side effects of being born addicted to methadone?

Methadone and Infant: This is a question that is best discussed with your neonatologist/high risk obstetrician and you if you are pregnant or thinking of becoming pregnant and are taking methadone. ...Read more

Dr. Stuart Wasser
638 doctors shared insights

Methadone (Definition)

Methadone is a synthetic opiate used for pain control and in the rehabilitation of opiate addicts. Methadone used in rehabilitation relieves craving, suppresses withdrawal symptoms, and blocks the euphoric effects associated with ...Read more