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Doctor insights on: Does It Make A Difference Whether I Take My Cymbalta In The Night Or The Morning

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I take cymbalta (duloxetine) 60 mg in the morning. I see some people take it at night before bedtime. Does it make a difference?

I take cymbalta (duloxetine) 60 mg in the morning. I see some people take it at night before bedtime. Does it make a difference?

Either one okay: You can take it either in morning or at bedtime. I usually advise my patients to take it in the morning so that it helps them get better sleep at night. Most doctors will suggest am dosing. However, I do not think it makes a big difference since we sometime prescribe it as twice a day. I think it is more of a matter of preference. If the am dose works fine for you, then i say stay with it! ...Read more

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Do most people take cymbalta (duloxetine) at night or in the morning?

Morning: The best benefit seems to result from morning dose. However some do prefer it at betime and that is acceptable too. ...Read more

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Cymbalta (duloxetine) has a half life around 12 hr. Does that mean you should take it twice a day, once morning and once night?

Cymbalta (duloxetine) has a half life around 12 hr.  Does that mean you should take it twice a day, once morning and once night?

SUSTAINED RELEASE: Cymbalta, (duloxetine) chemical name Duloxetine, is a selective serotonin reuptake inhibitor antidepressant. It affects the uptake and function of the chemical signals between nerve cells. It is also used for chronic pain conditions where it affects nerve cells in the body and brain similarly to how it works in the brain for depression. It is usually dosed once a day. It is in a delayed release capsule. ...Read more

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Do most people take cymbalta (duloxetine) in morning or night? This is my 2nd attempt on getting on this med fir anxiety. Can't tolerate most ssri.

Do most people take cymbalta (duloxetine) in morning or night?   This is my 2nd attempt on getting on this med fir anxiety.   Can't tolerate most ssri.

It varies: It is okay to take Cymbalta (duloxetine) any time of the day, as long as you don't skip doses. If you find that you feel better taking it a particular time of the day/night, then stick with that. Best wishes! ...Read more

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Have been prescribed Celexa & Cymbalta, (duloxetine) but neither instructs morning or night. Does it matter when I take them- what about 1 morning & 1 night?

Have been prescribed Celexa & Cymbalta, (duloxetine) but neither instructs morning or night.  Does it matter when I take them- what about 1 morning & 1 night?

That's good thinking: both of those drugs can cause sleepiness or can be activating, all that depends on the dose, the other medications you take, and your individual response to medication. Trying on one day and another the next in the morning would help you figure out how each affects you. When starting new drugs I prefer to try only one for a bit, then add the other. IfU have a rxn U need 2know which drug caused it. ...Read more

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Should i take cymbalta (duloxetine) in the morning or evening?

Should i take cymbalta (duloxetine) in the morning or evening?

Whichever works best: You may take it whichever way works best for you. Take it in the evening if it makes you tired or in the morning if it keeps you awake or you could divide the dose to a twice daily dosage if you would like. Please discuss it with your psychiatrist however before making any changes. ...Read more

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