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Doctor insights on: Does Interferon Beta Cause Changes In Bone Marrow Over Time And Is It Serious

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Does interferon beta cause changes in bone marrow over time and is it serious?

Does interferon beta cause changes in bone marrow over time and is it serious?

Rarely: More precisely interferon beta has rarely been associated with "pancytopenia" meaning a decrease in all the blood cell lines, platelets, white blood cells and red blood cells. It can be serious if undetected since low platelets can result in bleeding and low WBC counts can result in serious infection, but a patient on the drug can be monitored for this and the drug discontinued if problems occur. ...Read more

Interferon (Definition)

Interferons are a diverse group of proteins that belong to a class of glycoproteins known as cytokines. Interferons were first discovered for their ability to block viral replication within host cells. They also have been found to activate immune cells for many disease processes. There are several classes of interferons, types i, ii and iii, depending on ...Read more


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Can relocating from India to US increase risk of MS relapse? Disease is stable on Avonex (interferon beta 1a) in India. Environment Change = relapse? Shd I avoid travel?

Can relocating from India to US increase risk of MS relapse? Disease is stable on Avonex (interferon beta 1a) in India. Environment Change = relapse? Shd I avoid travel?

Advice: 1. OK to travel 2. Risk of relapse should be similar in US 3. Avonex is NOT my drug of choice, and will likely need to be changed in future due to low level of efficacy. Three oral drugs exist in US, and include Aubagio, Tecfidera, and Gilenya, (fingolimod) and might be a good choice. ...Read more

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Have external fixator in left wrist and left-sided numbness for hours after my avonex (interferon beta 1a) injection. Related? Can avonex (interferon beta 1a) cause infection in said situation

Have external fixator in left wrist and left-sided numbness for hours after my avonex (interferon beta 1a) injection. Related? Can avonex (interferon beta 1a) cause infection in said situation

Explanation: If you just started Avonex (interferon beta 1a) for ms, may be transient ms flares after the first series of injections, which is not unexpected. Would be surprised if your injection caused any infection, and do not believe the external fixator relates at all. However, I have a very negative opinion of avonex, (interferon beta 1a) which does not work very well to stabilize ms, as all the other dmt's work far better. Talk with doctor. ...Read more

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Betaseron (interferon beta 1b) adverse reactions?

Betaseron (interferon beta 1b) adverse reactions?

Multiple..: 1) depression 2) allergic reaction 3) injection site necrosis http://www.Rxlist.Com/betaseron-drug/side-effects-interactions.Htm. ...Read more

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Can I take betaseron (interferon beta 1b) while breastfeeding?

Can I take betaseron (interferon beta 1b) while breastfeeding?

No: Unfortunately, there are no great studies demonstrating that this medicine is not passed in breast milk, but due to its potentially harmful interactions with fetuses, it's best to not use it while lactating. The official statement is to "either discontinue lactation, or discontinue the drug." formula or human banked breast milk would be best in this case. ...Read more

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What effects does betaseron (interferon beta 1b) have on breastfeeding?

What effects does betaseron (interferon beta 1b) have on breastfeeding?

Interferon for MS?: It should be okay. No information is available regarding whether it can be passed onto an infant in mother's milk. No studies are available regarding harm in infants. Have your pediatrician monitor the progress during the health maintenance visits. ...Read more

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What is the structure of avonex (interferon beta 1a)? What does it do in the body?

What is the structure of avonex (interferon beta 1a)? What does it do in the body?

Response: Avonex, (interferon beta 1a) a minimally effective interferon, is intended to slow inflammatory cellular invasion of central nervous system in MS. An extremely poor choice these days in presence of 12 more effective drugs. Side effects such as general malaise, flu-like reactions, depression, thyroid issues, liver problems, fatigue and need to inject limit use. If you wish to view structure, visit Wikipedia. ...Read more

Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more


Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more