Doctor insights on:
Does Ig A Deficiency Cause Celiac
Inability to make a class of antibody (IgA) that plays a major role in mucosal immunity (gut and respiratory tract predominantly). May result in recurrent infection, but is often discovered incidentally. May also forecast the development of a more severe immune problem called combined variable immune deficiency (CVID) or be a risk factor for an anaphylactic reaction to ...Read more
Amino acids synthesi: Protein is necessary for the body to synthesize 13 Amino Acids and to break down polypeptide molecules into the nine essential Amino Acids that the body cannot manufacture on its own. Collectively, these acids constantly work to replenish tissue in the body, so they play an important role in the maintenance of healthy bones, muscles, and organs. The body also uses protein to produce hemoglobin. ...Read more
Harms sm. intestine: Celiac disease leads to inflammation and damage of the lining of the small intestine, which causes decreased absorption of nutrients, vitamins, iron, etc... The intestinal lining loses its microscopic "villi", which are tiny protrusions that maximize the absorptive surface area needed to absorb nutrients. A patient gets diarrhea, anemia, lactose intolerance, tummy aches, irritable bowels, etc... ...Read moreSee 1 more doctor answer
Can iron anemia deficiency due to bleeding polyps affect your immune system? Can Chrohns, Intestinal inflammation, and GI issues cause low IG levels?
No immune change: Very few situations can alter the immune system so that it is not functional. especially with bleeding polyps and iron deficiency anemia. Usually with malignancy causes problems not by eliminating the immune system but by temporarily blocking it. With Crohns and IBD there would be a tendency to respond by enhancing the immune IgG response as a means of defending against the inflammatory process ...Read more
Does iron deficiency anemia tend to cause subclinical hypothyroidism? Or does subclinical hypothyroidism make a person get iron deficiency anemia? Thanks
Low vitamin B12.: pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. ...Read more
Can silent celiac be present if IgA and IgG are <2 (negative)? And causing neuropathy, w/high b12.
Celiac disease: The only reliable diagnosis for celiac disease is based on intestinal biopsies showing inflammatory damage that resolves when on a gluten-free diet. Blood testing for anti-dpg ot ttg are suggestive if positive but not definitive (negative testing does not eliminate celiac). Genetic testing is useful since the absence of hla-dq 2 or 8 alleles makes celiac disease unlikely (. ...Read more
Not directly, but...: People who manage their diet to avoid gluten may risk becoming deficient in a variety of necessary nutrients. It's possible to learn how to have a varied, full range of foods, but it takes time and interest. Sun-sensitivity is a symptom of pellagra (a Niacin (vitamin b3) deficiency). It can be quite serious so eat tuna, salmon, or ground beef if you can, or snack on peanuts daily. ...Read more
YES!: Ppi's make it difficult for us to absorb B12 as gastric hydrochloric acid is needed to absorb B12 & minerals as well as digest protein. These drugs are dangerous to take for more than a few weeks! they increase risk of osteoporosis & serious infections. See http://bit.Ly/1607tg3 re: B12 & http://bit.Ly/1b1avqs & http://bit.Ly/1ach2tw re: the serious hazards of ppi's & safe &superior alternatives. ...Read more
The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read moreSee 1 more doctor answer
Required by nerves: This co-factor is needed by the nerves to stay healthy. Each nerve cell has a self repair system that relies on a variety of nutrients in our diet to provide the needed material to keep the walls intact and the cell working. Lack of B12 eventually causes that repair system to start breaking down and nerve cells malfunction or degenerate, leading to neurologic symptoms. ...Read moreSee 1 more doctor answer
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