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Doctor insights on: Does Ig A Deficiency Cause Celiac

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What IgA levels indicate celiac's or gluten sensitivity?

What IgA levels indicate celiac's or gluten sensitivity?

TTg-IgA: The IgA antibody to Tissue Transglutaminase is currently the best blood test to screen for Celiac disease. If this level is elevated, further evaluation should be considered. ...Read more

Dr. Zamaneh Mikhak
70 doctors shared insights

Iga Deficiency (Definition)

Inability to make a class of antibody (IgA) that plays a major role in mucosal immunity (gut and respiratory tract predominantly). May result in recurrent infection, but is often discovered incidentally. May also forecast the development of a more severe immune problem called combined variable immune deficiency (CVID) or be a risk factor for an anaphylactic reaction to ...Read more


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Does iron deficiency cause bloating?

Does iron deficiency cause bloating?

Not usually: but certain conditions like celiac disease (gluten allergy) can cause both iron deficiency and bloating. best to have your parent discuss this with your pediatrician. ...Read more

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Why does protein deficiency cause liver disease?

Why does protein deficiency cause liver disease?

Amino acids synthesi: Protein is necessary for the body to synthesize 13 Amino Acids and to break down polypeptide molecules into the nine essential Amino Acids that the body cannot manufacture on its own. Collectively, these acids constantly work to replenish tissue in the body, so they play an important role in the maintenance of healthy bones, muscles, and organs. The body also uses protein to produce hemoglobin. ...Read more

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How does celiac disease cause nutrient absorption?

How does celiac disease cause nutrient absorption?

Harms sm. intestine: Celiac disease leads to inflammation and damage of the lining of the small intestine, which causes decreased absorption of nutrients, vitamins, iron, etc... The intestinal lining loses its microscopic "villi", which are tiny protrusions that maximize the absorptive surface area needed to absorb nutrients. A patient gets diarrhea, anemia, lactose intolerance, tummy aches, irritable bowels, etc... ...Read more

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Does celiac disease cause nutrient absorption in children?

It Can: Only if you restrict the diet too significantly can there be nutritional issues. Substitute with an appropriate food or multivitamin. Please discuss with your doctor or request a dietitian consult. ...Read more

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Can iron anemia deficiency due to bleeding polyps affect your immune system? Can Chrohns, Intestinal inflammation, and GI issues cause low IG levels?

Can iron anemia deficiency due to bleeding polyps affect your immune system? Can Chrohns, Intestinal inflammation, and GI issues cause low IG levels?

No immune change: Very few situations can alter the immune system so that it is not functional. especially with bleeding polyps and iron deficiency anemia. Usually with malignancy causes problems not by eliminating the immune system but by temporarily blocking it. With Crohns and IBD there would be a tendency to respond by enhancing the immune IgG response as a means of defending against the inflammatory process ...Read more

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Can seborrheic dermatitis cause a positive tissue transglutaminase IgA antibody, low level?

Can seborrheic dermatitis cause a positive tissue transglutaminase IgA antibody, low level?

No: In and of itself , seborrheic dermatitis does not cause any significant immunologic disorders although certain diseases do have an association with seborrheic dermatitis-like rashes such as zinc deficiency syndromes and parkinsonism, for instance. ...Read more

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Does pernicious anemia cause high serum b12?

Does pernicious anemia cause high serum b12?

Low vitamin B12.: pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. ...Read more

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What can cause secondary (acquired) IgM deficiency? Cancer? Infections? Autoimmunity?

What can cause secondary (acquired) IgM deficiency?  Cancer?  Infections?  Autoimmunity?

Acquired is rare: The common primary igm deficiency is genetically transmitted , the acquired ( or secondary ) isolated with out other deficiencies , igm deficiency alone is are , usually due to infections like HIV , whipple's etc. ...Read more

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How common is celiac disease (gluten sensitivity)?

How common is celiac disease (gluten sensitivity)?

1 in 3,000: But still more people are allergic to wheat, which is a different problem with a similar treatment: avoid it! fyi the only other grains with they type of gluten to avoid in celiac sprue are rye and barley. ...Read more

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Can silent celiac be present if IgA and IgG are <2 (negative)? And causing neuropathy, w/high b12.

Can silent celiac be present if IgA and IgG are <2 (negative)? And causing neuropathy, w/high b12.

Celiac disease: The only reliable diagnosis for celiac disease is based on intestinal biopsies showing inflammatory damage that resolves when on a gluten-free diet. Blood testing for anti-dpg ot ttg are suggestive if positive but not definitive (negative testing does not eliminate celiac). Genetic testing is useful since the absence of hla-dq 2 or 8 alleles makes celiac disease unlikely (. ...Read more

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How does mild iron deficiency anemia affect hba1c levels?

How does mild iron deficiency anemia affect hba1c levels?

Mild effect: Studies have shown a mild effect of iron deficiency raising HGB a1c levels but it doesn't appear to be clinically significant in known diabetics. In other words we can still be guided by their hga1c levels even in the presence of iron deficiency. ...Read more

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Can celiac disease cause sun sensitivity?

Can celiac disease cause sun sensitivity?

Not directly, but...: People who manage their diet to avoid gluten may risk becoming deficient in a variety of necessary nutrients. It's possible to learn how to have a varied, full range of foods, but it takes time and interest. Sun-sensitivity is a symptom of pellagra (a Niacin (vitamin b3) deficiency). It can be quite serious so eat tuna, salmon, or ground beef if you can, or snack on peanuts daily. ...Read more

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Does ppi s cause B12 vitamin deficiency?

Does ppi s cause B12 vitamin deficiency?

YES!: Ppi's make it difficult for us to absorb B12 as gastric hydrochloric acid is needed to absorb B12 & minerals as well as digest protein. These drugs are dangerous to take for more than a few weeks! they increase risk of osteoporosis & serious infections. See http://bit.Ly/1607tg3 re: B12 & http://bit.Ly/1b1avqs & http://bit.Ly/1ach2tw re: the serious hazards of ppi's & safe &superior alternatives. ...Read more

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Do elevated gliadin antibodies IgG and IgA mean gluten sensitivity?

TTG: I woul recommend having a ttg IgA antibody and possible duodenal bx , in doing so a diagnosis of celiac disease can be made. If if asymptomatic, there may be benefit from a gluten free diet especially if small bowel inflammation noted. ...Read more

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How does pernicious anemia cause people to have achlorhydria?

How  does pernicious anemia cause people to have achlorhydria?

The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read more

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Wouldn't malnutrition due to Crohn's disease cause an abnormal Prealbumin blood level?

Wouldn't malnutrition due to Crohn's disease cause an abnormal Prealbumin blood level?

Pre-albumin / Crohns: Yes depending on level of inflammation in crohns disease. As a gastroenterologist I use pre-albumin in conjunction with other blood tests to see how my patients are responding to therapy. If inflammation is poorly controlled pre-albumin is usually low. ...Read more

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Why does vitamin B12 deficiency cause neurological symptoms?

Why does vitamin B12 deficiency cause neurological symptoms?

Required by nerves: This co-factor is needed by the nerves to stay healthy. Each nerve cell has a self repair system that relies on a variety of nutrients in our diet to provide the needed material to keep the walls intact and the cell working. Lack of B12 eventually causes that repair system to start breaking down and nerve cells malfunction or degenerate, leading to neurologic symptoms. ...Read more

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Dr. John Chiu
635 doctors shared insights

Celiac Disease (Definition)

An immune reaction to eating gluten, a protein found in ...Read more