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Does History Of Icp Cause Intrahepatic Cholestasis Of Pregnancy
Icp causes itching: I have only had one patient with icp in 27 years of practicing obstetrics. Diagnosis is made by elevated bile salts (detectable by lab test) and the treatment is cholestyramine. Pregnancy outcome should be unaffected by the condition. So icp is rare and makes you miserable, but should not affect your baby. One case however hardly makes me an expert so second opinions welcome. ...Read more
When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more
Delivery: It usually goes away at or shortly after delivery. ...Read more
Until pregnancy ends: Cholestasis of pregnancy is a considition which generally occurs in the 3rd trimester and is characterized by intense pruritis without rash and increase serum levels of free bile acids. The condition lasts until the pregnancy ends. The pruritis sometimes can be controlled with medications, such as ursodiol. ...Read more
NO: Cholestasis of pregnancy does not generally cause pain. The most common symptoms is pruritis (itching). It almost always starts with itching on the palms of the hands and soles of the feet, and it is first noticed at night. The itching spreads to other parts of the body over time. Treatment with ursodiol (bile salts) can improve symptoms. Consultation with a high risk OB is recommended. ...Read more
24-48 hrs: Usually all symptoms of intrahepatic cholestasis of pregnancy resolve within 24-48 hrs after delivery, in rare cases sx may continue to up to one week after and may signify retained placenta. But if you have this condition pregnancy needs to be monitored by obgyn very closely as poor outcomes for the baby are not uncommon if not monitored. ...Read more
Can cholestasis of pregnancy cause long term inflammation to common bile duct? Can hormones affect liver enzymes and itching during period?
Possibly: the itching is from the cholestasis as it causes the bike to go up and this causes the itching. The inflammation can persist, but can also resolve. External hormone use has to be processed by liver first, so they can place "pressure" on the liver, as can Tylenol, (acetaminophen) and any other medications typically. ...Read more
PBC Elevated LFT's: Primary biliary cirrhosis (pbc) itself is a terminal cirrhotic state of liver, requiring liver transplant. There is not much ast & alt enzymes left in liver to go up. Certain insults, can expedite liver damage, by elevated lft's: medicines metabolized by liver, alcohol, an obstruction in porta hepatis, ? Malignancy, need to be considered. ...Read more
Several: They depend on cause and age of patient. In preterm infants, it is frequently from prolonged use of TPN and late start of feeds. Majority resolve. In some cases it can cause gall bladder sludge, gall stones or inflammation/infection of the plumbing system of the liver (cholangitis). In extreme cases, these patients can develop cirrhosis and chronic liver failure and may need liver transplant. ...Read moreSee 1 more doctor answer
Have you noticed any links between the use of isotretinoin and the development of various liver/ biliary system disorders (i.E.: hepatic cholestasis)?
NO: Isotretinoin is one of the most researched medications on the planet. Roche , the initial company that made the medication, did tons of studies on this med. There have been reported cases of depression, ulcerative colitis, crohn's disease coming on while someone is on isotretinoin. Some of these cases were won in courts of law. Later studies suggested that these were probably coincidence. ...Read more
What are the lipid tests that can be ordered in case of prolonged diabetes with developing of ischmic heart disease ?
MRCP "Persistent mild dilation of the central intrahepatic duct. There are areas of mild narrowing & irregularity of the intrahepatic ducts & proximal common duct. No dilation of common bile duct. Gallbladder sludge is present." What causes this?
Nonspecific: I believe that the ductal findings are nonspecific. Sludge in the gall bladder can cause abdominal distress and indigestion. A gastroenterologist would sit down with the radiologist and review the images and decide whether more imaging studies like an MRI or liver biopsy are advisable depending upon your symptoms or lack of symptoms. ...Read more
Not fully understood: Preeclampsia and eclampsia are not fully understood. Neither are fully understood laboratory changes associated with it like changes in liver enzyme levels or platelet numbers nor why sometimes the liver is enlarged or the kidneys show signs of damage and at other times they don't. Effective treatment in almost all cases is removal of the placenta, with sooner or later recovery of the patient. ...Read more
In cirrhosis does the presence of ascites always indicate decompensation and is this considered a serious complication and stage of the disease?
It is concerning: Ascites- buildup of fluid in the abdominal cavity- can be a sign of serious decompensation in the liver function. This is usually seen in the later stages of liver failure. If this is seen you should let your doctor know right away. This is associated with decreased survival. However if the cause of the liver damage is found early-& treated this can delay progression. Cirrhosis can't be undone. ...Read moreSee 1 more doctor answer
Mostly: Severe hemolytic anemia overloads capacity of liver to process hemoglobin from ruptured blood cells. Disease of gall bladder, bile duct, pancreas can block the bile flow. Gilbert's disease can cause jaundice when liver function is otherwise normal. There are others. ...Read moreSee 1 more doctor answer
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