Doctor insights on:
Does Having Pernicious Anemia Lead To Fertility Problems
Yes indirectly: Pernicious anemia is a deficiency of vitamin B12 and or folate (folic acid) (another b vitamin) that can lead to significant medical problems many of which affect the nervous system. Folate (folic acid) is so critical to fetal neural development that the fda recommends that all women trying to conceive or pregnant take a Folic Acid supplement of 0.4 milligrams or 400 micrograms a day. ...Read more
2 years ago, I was told my B12 deficiency could lead to pernicious anemia. I stopped the B12 pills, my symptoms match, can I have this? B12 now fine.
I have symptoms of severe B12 deficiency/pernicious anemia but also derealization, brain damage, and heart problems could these occur from the B12 def.?
Yes except heart:
B12 deficiency can cause a variety of neurological symptoms including "derealization"; it can adversely affect brain function but that damage should be reversible. It can cause high homocysteine which increases risk of cardiovascular disease ; anemia puts stress on hearts, but it should not directly cause heart problems in someone your age. See
http://tinyurl. Com/ofaclgs ...Read more
Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them.
Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more
Not at all: Pernicious anemia results from poor dietary uptake of vitamin b12, usually from a loss of certain cells in your stomach. These cells secrete intrinsic factor, necessary for absorption of vitamin b12. Treatment is B12 shots, potentially. Leukemia is cancer. Treatment is chemotherapy. ...Read more
See below: B-12 anemia is a deficiency in vitamin b-12 (cobalamin). Pernicious anemia is a deficiency or lack in intrinsic factor (produced by cells in the stomach) which is a protein essential for absorption of vitamin B12 in the ileum (small intestine). Pernicious anemia requires replacement of intrinsic factor &/or b-12. B-12 anemia needs only b-12 supplementation. ...Read more
Can you clarify?: If you have pernicious anemia and aren't effectively treated, you will first lose your mind and then your life. If by "B12 intolerance" you simply mean you cannot absorb the vitamin orally, this is common and you'll need monthly injections. If you believe that the supplement makes you sick -- as it claimed on some "pop" websites -- I'm skeptical but you'll need to get specialist consultation. ...Read more
Low vitamin B12.: Pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. ...Read more
Possibly.: There appears to be some association between pernicious anemia and the risk of developing gastric cancer, but this is controversial. Pernicious anemia frequently develops with an autoimmune attack on certain gastric cells, which leads to vitamin B12 deficiency and later anemia. This autoimmune attack also leads to chronic gastritis, which can then progress to cancer. ...Read more
Some: Pernicious anemia is due to malabsorption of vitamin b-12 from the GI tract. It is a form of low blood cell count with associated symptoms of fatigue, paleness, breathing difficulties, etc. While not very common, all such patients should be evaluated by their doctor to give treatment for the pernicious anemia if that is the only problem and to discover any other problem. ...Read more
Best to see your OB: They will work with their hematology and perhaps GI colleagues to help guide decisions during your pregnancy. With modern medical and supportive care, I am not aware of a contraindications to natural childbirth in the setting of pernicious anemia. I suspect that you are already receiving folate (folic acid) supplementation from your doctors, which can ameliorate some pernicious anemia sequelae. ...Read more
Pernicious Anemia: Pernicious anemia is not inheritated to my knowledge. It is usually caused by lack of the vitamins b 12 in diet (by vegetarians) or lack of intrinsic factors in autoimmune atrophic gastritis or in patients who had part of the stomach cut off for bariatric surgery (to reduce weight) or as surgical treatment for peptic or gastric ulcers (gastrostomy). ...Read more
The two are linked:
This finding goes back to 1964, believe it or not:
http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/pmc1552204/? Page=1
there are autoimmune antibodies in both conditions, so while one might not cause the other, the two are related. ...Read more
Low vitamin B12: Pernicious anemia is a condition in which the body is unable to absorb vitamin B12 through the stomach due to loss of a protein called intrinsic factor in the stomach. Treatment invovles replacing b! 2 through injections or nasal sprays- taking oral pills is ineffective. ...Read more
Pernicious anemia...: Is due to B12 def arising from loss of intrinsic factor production by parietal cells in the stomach and required for B12 absorption in the gut. Anything that produces B12 def can cause these symptoms. Classically, pa is one such diagnosis that is due to destruction of parietal cells by the immune system (ie., an autoimmune disorder). I suspect elevated igg is true, true and unrelated. See your dr. ...Read more
Pernicious = Vit B12: Megaloblastic anemia refers to any condition which causes large red blood cells (folate (folic acid) deficiency, vitamin B12 deficiency, etc.) pernicious anemia can be thought of as a *type* of megaloblastic anemia which is caused by vitamin B12 deficiency secondary to malabsorption. ...Read more
Big RBC: Pernicious anemia is deficiency of vitaminb12 due to autoimmune attack on cell of the stomach and antibody against intrinsic factor- presented with megaloblastic anemia. Pa is only one of the causes of megaloblastic anemia- however other causes that can cause def vitb12, or folate (folic acid) or other drug eg. Bactrim- that inhibits dna synthesis in RBC production also can cause megaloblastic anemia. ...Read more
Treatment: Pernicious anemia is the result of loss of B12 in your system. It can result from severe dietary restrictions, genetic or bowel disorders, bowel resections and bariatric surgery. You must be treated for the cause and the effects of B12 deficiency, which should prevent anemia and neurologic damage from these problems. A simple blood test for B12 level is available. ...Read more
What else can help with pernicious anemia other than b12 injections? Have read that in UK the type of b12 used in injections isn't very good. True?
Bunk: Stop reading internet disinformation. Back in the old days, pernicious anemia assured a terrible lingering death preceded by insanity. The very fact that "natural healing" types make up stuff about the injections that have saved millions of lives show how successful they are. Forgive my frankness and remember that the law requires your physician to be honest while crooks have no accountability. ...Read more
I have pernicious anemia. I am supposed to take B12 shots. I have some left expired 8/12. Is it OK to take? And what size syringe. 1cc intramusc
B12: Expired medications should not be taken. They may be less potent, or with injectables, may have increased risk of contamination ...Read more
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