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Doctor insights on: Does Having Pernicious Anemia Lead To Fertility Problems

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Does having pernicious anemia lead to fertility problems?

Does having pernicious anemia lead to fertility problems?

Yes indirectly: Pernicious anemia is a deficiency of vitamin B12 and or folate (folic acid) (another b vitamin) that can lead to significant medical problems many of which affect the nervous system. Folate (folic acid) is so critical to fetal neural development that the fda recommends that all women trying to conceive or pregnant take a Folic Acid supplement of 0.4 milligrams or 400 micrograms a day.

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Dr. Khurram Rehman
1,236 Doctors shared insights

Infertility (Definition)

Infertility = inability to conceive or if a woman under age 35 - not being able to get pregnant after having regular sex for a year without birth control use. For a woman over 35 years old is not being able to get pregnant after having regular ...Read more


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I have pernicious anemia. Can it cause bone marrow problems?

I have pernicious anemia. Can it cause bone marrow problems?

Yes: It can cause what is known as megaloblastic anemia. The red blood cells are not produced normally and can also lead to other blood issues, such as low platelets. Can be fixed by replacing vitamin B12 or cyanocobalamin.

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I have symptoms of severe B12 deficiency/pernicious anemia but also derealization, brain damage, and heart problems could these occur from the B12 def.?

I have symptoms of severe B12 deficiency/pernicious anemia but also derealization, brain damage, and heart problems could these occur from the B12 def.?

Yes except heart: B12 deficiency can cause a variety of neurological symptoms including "derealization"; it can adversely affect brain function but that damage should be reversible. It can cause high homocysteine which increases risk of cardiovascular disease ; anemia puts stress on hearts, but it should not directly cause heart problems I someone your age. See http://bit. Ly/1hlbiaz.

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What symptoms of pernicious anemia are the most common?

What symptoms of pernicious anemia are the most common?

Fatigue: In pernicious anemia, there is no vitamin B12 absorption which causes low red blood cell production and leads to severe anemia. This causes fatigue most comonly.

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Does methadone cause pernicious anemia?

Does methadone cause pernicious anemia?

Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD.

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Is it true that leukemia and pernicious anemia the same thing?

Not at all: Pernicious anemia results from poor dietary uptake of vitamin b12, usually from a loss of certain cells in your stomach. These cells secrete intrinsic factor, necessary for absorption of vitamin b12. Treatment is B12 shots, potentially. Leukemia is cancer. Treatment is chemotherapy.

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What's the difference between pernicious anemia and B12 anemia?

What's the difference between pernicious anemia and B12 anemia?

See below: B-12 anemia is a deficiency in vitamin b-12 (cobalamin). Pernicious anemia is a deficiency or lack in intrinsic factor (produced by cells in the stomach) which is a protein essential for absorption of vitamin B12 in the ileum (small intestine). Pernicious anemia requires replacement of intrinsic factor &/or b-12. B-12 anemia needs only b-12 supplementation.

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What will happen to people who have pernicious anemia but are intolerant to b12?

What will happen to people who have pernicious anemia but are intolerant to b12?

Bad blood and nerves: B 12 is a vitamin that essential for life. B12 deficiency if goes untreated can lead to severe anemia and neuropathy, not to mention dementia. try another formulation of B12

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Please explain what happens to people who have pernicious anemia but are intolerant to b12?

Please explain what happens to people who have pernicious anemia but are intolerant to b12?

Can you clarify?: If you have pernicious anemia and aren't effectively treated, you will first lose your mind and then your life. If by "B12 intolerance" you simply mean you cannot absorb the vitamin orally, this is common and you'll need monthly injections. If you believe that the supplement makes you sick -- as it claimed on some "pop" websites -- I'm skeptical but you'll need to get specialist consultation.

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Best way to get rid of pernicious anemia?

Vitamin B12: Go to your md or hematologist. Get started on vitamin B12 either by nasal inhalation (nascobal) or by injection. This shold be easy to treat.

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Does pernicious anemia cause high serum b12?

Low vitamin B12.: Pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue.

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Since having pernicious anemia I get drunk quicker?

Maybe a little.: If you have a significant anemia with low red blood cells I suppose you could feel a little more woozy with a smaller amount of alcohol, but unless you are pretty anemic I would not expect this to be a signifiant effect.

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Is there a link between pernicious anemia and cancer?

Possibly.: There appears to be some association between pernicious anemia and the risk of developing gastric cancer, but this is controversial. Pernicious anemia frequently develops with an autoimmune attack on certain gastric cells, which leads to vitamin B12 deficiency and later anemia. This autoimmune attack also leads to chronic gastritis, which can then progress to cancer.

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Do doctors see a lot of patients with pernicious anemia?

Do doctors see a lot of patients with pernicious anemia?

Some: Pernicious anemia is due to malabsorption of vitamin b-12 from the GI tract. It is a form of low blood cell count with associated symptoms of fatigue, paleness, breathing difficulties, etc. While not very common, all such patients should be evaluated by their doctor to give treatment for the pernicious anemia if that is the only problem and to discover any other problem.

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If I have pernicious anemia should I give birth naturally?

Best to see your OB: They will work with their hematology and perhaps GI colleagues to help guide decisions during your pregnancy. With modern medical and supportive care, I am not aware of a contraindications to natural childbirth in the setting of pernicious anemia. I suspect that you are already receiving folate (folic acid) supplementation from your doctors, which can ameliorate some pernicious anemia sequelae.

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My mom gets pernicious anemia, so am I likely to get it later?

Pernicious Anemia: Pernicious anemia is not inheritated to my knowledge. It is usually caused by lack of the vitamins b 12 in diet (by vegetarians) or lack of intrinsic factors in autoimmune atrophic gastritis or in patients who had part of the stomach cut off for bariatric surgery (to reduce weight) or as surgical treatment for peptic or gastric ulcers (gastrostomy).

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Is it possible for chronic gastritis to cause pernicious anemia?

Is it possible for chronic gastritis to cause pernicious anemia?

The two are linked: This finding goes back to 1964, believe it or not: http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/pmc1552204/? Page=1 there are autoimmune antibodies in both conditions, so while one might not cause the other, the two are related.

Dr. Khurram Rehman
1,626 Doctors shared insights

Fertility (Definition)

Fertility refers to the ability of a woman to conceive a child, or to the ability of a man to ...Read more


Pernicious Anemia (Definition)

A decrease in red blood cells when the body can't ...Read more