Doctor insights on:
Does Having Pernicious Anemia Lead To Fertility Problems
Yes indirectly: Pernicious anemia is a deficiency of vitamin B12 and or folate (folic acid) (another b vitamin) that can lead to significant medical problems many of which affect the nervous system. Folate (folic acid) is so critical to fetal neural development that the fda recommends that all women trying to conceive or pregnant take a Folic Acid supplement of 0.4 milligrams or 400 micrograms a day.See 1 more doctor answer
2 years ago, I was told my B12 deficiency could lead to pernicious anemia. I stopped the B12 pills, my symptoms match, can I have this? B12 now fine.
Huh?: Pernicious anemia is B12 deficiency because of lack of absorption so you need B12 given as a shot. That should take care of any symptoms.
I have symptoms of severe B12 deficiency/pernicious anemia but also derealization, brain damage, and heart problems could these occur from the B12 def.?
Yes except heart: B12 deficiency can cause a variety of neurological symptoms including "derealization"; it can adversely affect brain function but that damage should be reversible. It can cause high homocysteine which increases risk of cardiovascular disease ; anemia puts stress on hearts, but it should not directly cause heart problems I someone your age. See http://bit. Ly/1hlbiaz.
Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD.
See below: B-12 anemia is a deficiency in vitamin b-12 (cobalamin). Pernicious anemia is a deficiency or lack in intrinsic factor (produced by cells in the stomach) which is a protein essential for absorption of vitamin B12 in the ileum (small intestine). Pernicious anemia requires replacement of intrinsic factor &/or b-12. B-12 anemia needs only b-12 supplementation.
Can you clarify?: If you have pernicious anemia and aren't effectively treated, you will first lose your mind and then your life. If by "B12 intolerance" you simply mean you cannot absorb the vitamin orally, this is common and you'll need monthly injections. If you believe that the supplement makes you sick -- as it claimed on some "pop" websites -- I'm skeptical but you'll need to get specialist consultation.
Low vitamin B12.: Pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue.
Possibly.: There appears to be some association between pernicious anemia and the risk of developing gastric cancer, but this is controversial. Pernicious anemia frequently develops with an autoimmune attack on certain gastric cells, which leads to vitamin B12 deficiency and later anemia. This autoimmune attack also leads to chronic gastritis, which can then progress to cancer.See 1 more doctor answer
Some: Pernicious anemia is due to malabsorption of vitamin b-12 from the GI tract. It is a form of low blood cell count with associated symptoms of fatigue, paleness, breathing difficulties, etc. While not very common, all such patients should be evaluated by their doctor to give treatment for the pernicious anemia if that is the only problem and to discover any other problem.
Best to see your OB: They will work with their hematology and perhaps GI colleagues to help guide decisions during your pregnancy. With modern medical and supportive care, I am not aware of a contraindications to natural childbirth in the setting of pernicious anemia. I suspect that you are already receiving folate (folic acid) supplementation from your doctors, which can ameliorate some pernicious anemia sequelae.
Pernicious Anemia: Pernicious anemia is not inheritated to my knowledge. It is usually caused by lack of the vitamins b 12 in diet (by vegetarians) or lack of intrinsic factors in autoimmune atrophic gastritis or in patients who had part of the stomach cut off for bariatric surgery (to reduce weight) or as surgical treatment for peptic or gastric ulcers (gastrostomy).
The two are linked: This finding goes back to 1964, believe it or not: http://www. Ncbi. Nlm. Nih. Gov/pmc/articles/pmc1552204/? Page=1 there are autoimmune antibodies in both conditions, so while one might not cause the other, the two are related.
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