Doctor insights on:
Does Having Only One Kidney Lower My Erythropoietin Production
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
Can EPO abuse stop the kidneys from producing their own EPO once drug use is ended i've read plenty of research about erythropoietin abuse by athletes, and there is consensus that one of the big risks is polycythemia and the possibility of strokes, hypert
Yes, : Yes, once exogenously administered erythropoietin is stopped, assuming that the patient's kidneys are normal (where erythropoietin is primarily made), they should resume making erythropoietin on their own. Erythropoietin also known as epo, is a hormone that controls erythropoiesis, or red blood cell production. ...Read more
Hypoxia: This is a very complex process. The simplest answer is: hypoxia (low oxygen tension, anemia) stimulates HIF production (hopoxia-inducible factor) which then stimulates epo release from the kidney. Another protein called VHL inhibits HIF action on epo (negative regulator). Mutation of VHL can cause excessive epo release, resulting in congenital erythrocytosis (a rare genetic disorder). ...Read more
Possibly..: It depends on your residual kidney function, if you are anemic, and if anemia is present without another cause. If you have decreased kidney function which is determined by your creatinine level (it would be elevated), then you should see a nephrologist who can recommend epo if necessary. ...Read more
Anemia in CKD: Chronic kidney disease (ckd) anemia is caused by the diseased kidneys not being able to make the hormone, erythropoietin (e). E stimulates the bone marrow to make new red blood cells. Epogen (epoetin alfa) is a man made drug that replicates e's affects on the bone marrow and is given to both CKD and dialysis patients to treat their anemia. ...Read moreSee 1 more doctor answer
Very common: As the kidneys fail the production of erythropoetin (procrit (epoetin alfa) and epogen) falls off and anemia results.With replacement anemia and transfusion are avoided late stage kidney diease patients get treated with these drugs and almost all end stage renal failure patients. These drugs do nothing for kidney disease, they just fix the anemia. ...Read moreSee 1 more doctor answer
Can EPO secretion be low while kidneys and liver normal. Creatinine normal an kidney scan normal. Am 70 yrs?
Probably not key: I've been following your questions. Especially at age 34, anemia due simply to lack of erythropoietin is extremely uncommon, kidney troubles or no. You need to look for some other cause. Erythropoietin itself is produced irregularly and unless it's way below the reference range (which is set so that several % of healthies fall outside), I'd consider ignoring the result. ...Read more
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