Doctor insights on:
Does Having Only One Kidney Lower My Erythropoietin Production
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
Can EPO abuse stop the kidneys from producing their own EPO once drug use is ended i've read plenty of research about erythropoietin abuse by athletes, and there is consensus that one of the big risks is polycythemia and the possibility of strokes, hypert
Yes, : Yes, once exogenously administered erythropoietin is stopped, assuming that the patient's kidneys are normal (where erythropoietin is primarily made), they should resume making erythropoietin on their own. Erythropoietin also known as epo, is a hormone that controls erythropoiesis, or red blood cell production. ...Read more
Hypoxia: This is a very complex process. The simplest answer is: hypoxia (low oxygen tension, anemia) stimulates HIF production (hopoxia-inducible factor) which then stimulates epo release from the kidney. Another protein called VHL inhibits HIF action on epo (negative regulator). Mutation of VHL can cause excessive epo release, resulting in congenital erythrocytosis (a rare genetic disorder). ...Read more
Possibly..: It depends on your residual kidney function, if you are anemic, and if anemia is present without another cause. If you have decreased kidney function which is determined by your creatinine level (it would be elevated), then you should see a nephrologist who can recommend epo if necessary. ...Read more
Anemia in CKD: Chronic kidney disease (ckd) anemia is caused by the diseased kidneys not being able to make the hormone, erythropoietin (e). E stimulates the bone marrow to make new red blood cells. Epogen (epoetin alfa) is a man made drug that replicates e's affects on the bone marrow and is given to both CKD and dialysis patients to treat their anemia. ...Read moreSee 1 more doctor answer
Very common: As the kidneys fail the production of erythropoetin (procrit (epoetin alfa) and epogen) falls off and anemia results.With replacement anemia and transfusion are avoided late stage kidney diease patients get treated with these drugs and almost all end stage renal failure patients. These drugs do nothing for kidney disease, they just fix the anemia. ...Read moreSee 1 more doctor answer
Can EPO secretion be low while kidneys and liver normal. Creatinine normal an kidney scan normal. Am 70 yrs?
Probably not key: I've been following your questions. Especially at age 34, anemia due simply to lack of erythropoietin is extremely uncommon, kidney troubles or no. You need to look for some other cause. Erythropoietin itself is produced irregularly and unless it's way below the reference range (which is set so that several % of healthies fall outside), I'd consider ignoring the result. ...Read more
What causes EPO level to drop. Can it be something not serious. Kidneys scan and ceatinine level in blood normal. Got moderate anemia. Epo low. 70 yrs?
Anemia in a 70'er: The 70 year old person likely has chronic kidney disease (CKD), despite having a normal level creatinine. Have that person see a nephrologist for a 24 hour urine for creatinine clearance to assess the person's kidney function. It the glomerular filtration rate (GFR) is ...Read more
If needed can take: Erythropoietin is used for promoting red blood cells. Since premature infants can have anemia, as well as pediatric patients undergoing chemotherapy, it is a valuable tool. It has been approved by the FDA for these reasons. It has also been approved for pediatric renal disease. I hope this helps you. I would hope that you are not having to deal with these problems but if so, I wish you well. ...Read more
Kidney failure: Erythropoietin is commonly used in people with anemia due to kidney failure. Other uses include anemia associatid with hiv, chemotherapy and some types of bone marrow diease. It may also be used pre-surgically in certain selected patients. It has also been used improperly as a performance enhancing agent in competative sports. ...Read moreSee 1 more doctor answer
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