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Doctor insights on: Does Gallbladder Disease Have A Genetic Component

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Does gallbladder disease have a genetic component?

Does gallbladder disease have a genetic component?

Yes: Classically this was demonstrated in the pima indian population, but it is common to have a familial trend in non-native americans as well. ...Read more

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Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


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Does Parkinson's disease have a genetic component?

Does Parkinson's disease have a genetic component?

Yes!!: Current thought says many factors are involved. Pd is more common in areas with high agricultural chemical use & in those working with heavy metals or toxic chemicals. We also know that genetics are involved with several identified mutations causing higher susceptibility & rare families with dominantly inherited pd. I believe the key & cure of pd will be found using genetic breakthroughs. ...Read more

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Is there a large genetic component to cerebrovascular disease?

Is there a large genetic component to cerebrovascular disease?

Not really: Though there are rare genetic stroke syndromes (eg cadasil), for the vast majority of strokes, risk factors with a strong genetic component (hypertension , diabetes, high cholesterol) are the much bigger contributors to strokes and heart attacks often running in families (getting these diseases increases risk of stroke). ...Read more

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Can everyone get celiac disease, or is it a disorder of our genes?

Can everyone get celiac disease, or is it a disorder of our genes?

Genetic & hereditary: Celiac disease is hereditary and runs in families. The genes seen in patients are hla-dq2 and hla-dq8. Patients with only one copy of either gene tend to have milder symptoms, but patients with 2 copies of either gene, or 1 copy of both genes, have more severe disease. Celiac disease can occur rarely in persons without these genes. ...Read more

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How likely is it that i could have inherited an auto immune disease from my family?

How likely is it that i could have inherited an auto immune disease from my family?

Yes.: Some autoimmune diseases are very hereditable, some to a lesser extent. But the answer is yes! keep in mind that type 2 diabetes is much more likely to be passed down than most autoimmune diseases! ...Read more

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How does inheritance of a mitochondrial disease work?

How does inheritance of a mitochondrial disease work?

Maternal and Regular: A few mitochondrial diseases are passed from the mother to all of her children. This is because certain mitochondrial genes are inherited from the mitochondria in the egg's cytoplasm (outside the "nucleus" that contains the regular genes). Other mitochondrial diseases are inherited the regular way, from the genes in the egg "nucleus" and in the sperm, that code for new mitochondria in the embryo. ...Read more

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Does multiple sclerosis have a hereditary component?

Does multiple sclerosis have a hereditary component?

Yes: No single gene for MS has been found or likely to be found. Multiple genes have been identified which in different population studies worldwide seem to increase risk or protect against ms. The vast majority of these genes relate to immune system function. Genetic background, combined with environmental trigger likely trigger this disorder. ...Read more

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Is pancreatic disease an environmentally-induced disease or a hereditary disease?

Is pancreatic disease an environmentally-induced disease or a hereditary disease?

Pancreas: The simple answer is yes (environment), and yes (hereditary), but it could be nothing or something unrelated. I suggest you have your PC refer you to a gastroenterologist. ...Read more

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Is there a clear link between a possible celiac disease or even gluten sensitivity and recurrent/chronic idiopathic pericarditis?

Is there a clear link between a possible celiac disease or even gluten sensitivity and recurrent/chronic idiopathic pericarditis?

Autoimmune: The possible link is that they both can be due to autoimmune activity -- talk with your doctor and beware of rheumatoid arthritis and/or lupus or sarcoidosis. ...Read more

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If I have an elevated transglutaminase iga, hypothyroidism, and a mother with celiac disease. Is the likelihood that I have celiac disease.?

If I have an elevated transglutaminase iga, hypothyroidism, and a mother with  celiac disease.  Is the likelihood that I have celiac disease.?

Yes, but ...: While your database is highly suggestive of a person at risk for celiac disease, the diagnosis still hinges on a diagnostic small bowel biopsy. Once the diagnosis is secure, a gluten-free diet should then result in a drop in tissue transglutaminase titer. ...Read more

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Does either sex have more propensity toward a certain vascular disease?

Does either sex have more propensity toward a certain vascular disease?

Male/atherosclerosis: This depends on the cause and location of periphral arterial disease. Most common seen as atherosclerosis in lower extremities and that is more common in men although the outcome in females is worse. So what kind you are asking about ? ...Read more

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If psoriatic arthritis is a "t" cell malfunction, does exercise have benefit?

If psoriatic arthritis is a "t" cell malfunction, does exercise have benefit?

Yes: Exercise, when properly designed to be low impact, is good for not just arthritis but also your wellbeing and self esteem. Medication is still given to make exercise less painful. Exercise alone will not be enough to treat psoriatic arthritis unfortunately. ...Read more

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A friend's child has been diagnosed with SMA (spinal muscular atrophy). Does this happen to be a mitochondrial disease?

A friend's child has been diagnosed with SMA (spinal muscular atrophy). Does this happen to be a mitochondrial disease?

Most are gene mutatn: There are many subtypes of spinal muscular atrophy.Gene mutations have been associated with specific chromasomes including the x, 5th, 11th, 12th& 20th. This defect is generally passed as an autosomal recessive or x linked disorder. Other forms are possible. ...Read more

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Does a genetic test exist for the disease achromatopsia, or colorblindess?

Does a genetic test exist for the disease achromatopsia, or colorblindess?

Yes: Mutations in one of these several genes will cause colorblindness. These are autosomal recessive mutations. The genes are: achm2-alpha subunit of the cone photoreceptor cgmp-gated cation channel, on chromosome 2q11; achm3- cngb3 gene, the beta subunit of the cone cyclic nucleotide-gated cation channel, on chromosome 8q21; achm4- gnat2 gene, Alpha subunit of cone transducing, on chromosome 1p13. ...Read more

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Please explain why is cancer classified as a disease instead of a genetic defect?

That is an AWESOME..: ...Question! cancer is, after all, caused by changes (mutations) in certain genes that control the way cells behave. These changes usually develop during our life although sometimes they are inherited from our parents. The role of genetics in oncology (and probably other specialties) grows in importance with each passing year so the boundary between those 2 things can be hard to draw. ...Read more

Dr. Suzanne Galli
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Gallbladder (Definition)

The gallbladder is a sac-like structure located under the right lobe of the liver. It is attached to the common bile duct via the cystic duct. The gallbladder can store bile when the bile is not needed, and can squeeze bile into the bile duct and intestine for digestion when a person eats larger ...Read more


Genetic Linkage (Definition)

Genetic linkage is the tendency of genes that are located proximal to each other on a chromosome to be inherited together during meiosis. Genes whose loci are nearer to each other are less likely to be separated onto different chromatids during chromosomal crossover, and are therefore said ...Read more