Doctor insights on:
Does Fetal Karyotype Cause Stillbirth
Several.: Obstetric complications (abruption, multiple gestation, preterm birth - 29%), placental disease and fetal growth restriction (fgr - 24%), fetal genetic/structural abnormalities (14%), maternal/fetal infection (13%), umbilical cord abnormalities (10%), hypertensive disorders (9%), other maternal medical conditions (8%). One third/fourth of cases remain undiagnosed/idiopathic. @34 weeks fgr likely. ...Read more
2 early MCs, heartbeat seen in 2nd case, no live birth, turner's synd in fetus 2nd case, karyotyping & antiphosopolipid normal. Way fwd? More tests?
Try again: Abnormal chromosome patterns are seen in many of the MC's studied, so this would not be unexpected. If both you and spouse have been karyotyped & normal, you are not carrying a translocation that would doom you both to expect MC's.Consult the clinical genetics department at Toronto Children's if you have not already and see if their is anything more they recommend. ...Read moreSee 1 more doctor answer
3 early MCs no live birth. 32yrs. All tests normal autoimmune, antiphosopolipid, hormonal, karyotyping. Turner's in 1 fetus. Should we try again & how?
Yes: Don't give up, get followed by infertility/hi risk obstetrics doctor, at one point a medical geneticist input might be needed. For genetic / chromosomal disorders PIGD, Pre- Implantation Genetic Diagnosis can be resorted to so as not implant an embryo with a known major genetic/chromosomal disease, good luck ...Read more
I am 18 weeks. Fetus has not stopped excessively moving for over a week. It seems to get worse when I move positions. Can this result in stillbirth?
Baby moving...: After 17 weeks of pregnancy it is usually when you become aware of your baby moving inside of you. They can move a lot and it is not a sign of miscarriage or stillbirth. The opposite is true. Once you start feeling the baby moving, if it stops moving that is a dangerous sign. If you experience vaginal bleeding, severe pain, then those are also red flags and you should see OB. ...Read more
2 early MC, heartbeat seen 2nd case, no live birth, turner's synd in fetus 2nd case, karyotyping & immunological tests normal. Way fwd? More tests?
Maternal fetal medicine: specialist is what you need with your high risk pregnancies, if you don't have one available in your area please seek advice in a teaching hospital ...Read more
If parents' karyotyping is normal, what are the chances for recurrent early miscarriages due to chromosomal problems in fetus? Pls answer as clearly
Ans: There is always a possibility of a mutation. This cannot be predicted. However just because on the outside you are normal does not mean you do not carry a recessive gene. You and your partner can have gene mapping. But again remember thecwayvthe chromosomes line up is chance. But if you have abnormal genes you can put a percentage on the chance of that gene showing up. Again all a toss of the coin ...Read more
3 early MCs no live birth 32yrs old. Parents karyotyping normal but fetus showed turner's once & trisomy14 next one. Way fwd pls list tests/precaution?
Not exactly...: ..."karyotype" but a different kind of genetic test: http://www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc1715396/. ...Read more
3 miscarriages. Fetal karyotyping normal. D&c revealed uterine septum, but have healthy 7 y/0. What tests should i/we have next? $ is an issue.
Depends on you: To some extent you already have a good deal of information.You know that you can carry a baby to a healthy delivery. You also know you have a structural uterine defect that may cause a miscarriage. I'm not aware if they could reduce or remove your septum, or if such surgery would help.That may be a reasonable thing to discuss with your doc. ...Read more
3 MCs no live birth. 2 MCs turner's & trisomy14 in fetus. Parents karyotyping normal. What other genetic tests shld be done. Risk of abnormal child ?
5 months pregnant. On amniotic fluid sample test, "fetal karyotype was found to be 47, ##, +21 indicating down syndrome.". Should i go for abortion?
Personal decision: Yes, your child has down's syndrome. I have no idea how those children are treated in india. However, they are the most loving, kind people i care for. They have the capacity for love and joy unlike any of my other patients. Will the child require extra care and have different needs - absolutely. Only you can decide if you have the capacity to provide this and continue the pregnancy. ...Read moreSee 2 more doctor answers
Kick Counting: Fetal movement is reassuring. Babies that are in trouble stop moving, usually awhile before they are at risk of stillbirth. Monitoring fetal movement is a way to make sure that baby is doing well without hooking you up to a fetal monitor. If your monitoring indicates that baby isn't moving enough, you can go to the hospital for electronic fetal monitoring. Best wishes! ...Read more
I had a stillbirth due to a placenta abruption. NO known cause.One healthy birth previously. Would I be likely to have another abrupt or healthy preg?
Abruption chances: First of all, I am sorry for your loss. The risk for a recurrent complicated placental abruption in your next pregnancy is about 33/1000. Special surveillance would need to be undertaken about 3 months prior to the gestational age of the baby you lost due to the first placental abruption. Best of luck to you. ...Read more
With difficulty: Unfortunately it's not always evident. Examination of the stillborn sometimes shows us cord problems or obvious birth defects. The placenta is examined for problems, an autopsy can be ordered on the infant looking for birth defects. Chromosomes & blood tests looking for abnormalities (diabetes, lupus, infection, etc) are also done. However, many times the reason is unexplained or unclear. ...Read more
Chances: If you become infected during around the time of conception there is a less than 5% chance that your baby will also be infected. During the 3rd trimester there is a 65% chance your baby will also be infected. However, babies infected duirng later pregnancy are less likely to develop serious health problems. ...Read more
There R multiple causes of stillbirth, cord knot, infection, IUGR etc, but in those with unknown causes, is there a theory on what might be thecause?
Unknown=unknown: The more advances we make in genetic analysis & general study of fetal development the more of these cases will move from unknown to known. I watched a monitor abnormality during labor turn out to be a baby gripping his cord hard during contractions, causing a dangerous reduction in heart rate.That kid turned out fine, but it points out that sometimes we can't find evidence after the fact ...Read moreSee 1 more doctor answer
No: Although legionnaires' can have long-term effects, particularly on the elderly or the chronically ill, these effects are typically fatigue or neurologic symptoms. In the immunosuppressed (hiv patients, those on certain medications, or the severely ill), the bacterium has been known to spread to several organs only on very rare occasions, and no involvement of the uterus has been reported. ...Read moreSee 1 more doctor answer
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