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Doctor insights on: Does Everyone Gain Weight On Zoloft

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Do people lose or gain weight on zoloft (sertraline)?

Do people lose or gain weight on zoloft (sertraline)?

Gain: There is more of a tendency to gain weight on zoloft (sertraline) (although some people have lost weight on it.). ...Read more

Dr. Donald Jacobson
1,039 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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Does Zoloft (sertraline) make you gain weight? I've put on 30 lbs in two months and i can't loose it

Zoloft (sertraline) weight gain: Some people are very sensitive to mental medicines and would gain weight even with meds that are not kwown to make people gain weight. If you already have a weight issue and cannot lose weight easily, zoloft (sertraline) can also cause you some weight gain even thought it causes the least of that. If you already have a healthy lifestyle, please make it better, if not then try to adopt a healthy one. ...Read more

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Went up to 150 zoloft (sertraline). Gained weight fairly quickly. Went back down to 100. Should i continue to gain weight? Or will it subside?

No clear answer for: This. According to a study published in the journal of clinical psychiatry the average weight gain was 0.1% after > 1 year on zoloft (sertraline). 4.5% people treated with zoloft (sertraline) had a significant weight gain in one study. Weight gain is more likely if the person is taking zoloft (sertraline) for 6 months or longer. There are some people who experience increased carbohydrate craving on zoloft (sertraline). However, mechanism for weight. ...Read more

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I've been on Zoloft (sertraline) for a few yrs. I have noticed weight gain. I want to switch to something that won't make me gain, what works best for my age? 17.

I've been on Zoloft (sertraline) for a few yrs. I have noticed weight gain. I want to switch to something that won't make me gain, what works best for my age? 17.

Talk w/psychiatrist: This is something you need to discuss with your own psychiatrist, preferably an adolescent psychiatrist. Some medications have additional risks in young people, and you want to be safe and well. Lexapro (escitalopram) is a reasonable choice in adults, but reviewing your concerns with your own doctor would be better than asking doctors who don't know you (like us on healthtap). Good luck! ...Read more

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Would i gain weight or lose weight while taking zoloft (sertraline)?

Would i gain weight or lose weight while taking zoloft (sertraline)?

Possibly gain but...: About 25% of those who take zoloft (sertraline) gain 10 pounds or more, but the good news is 75% don't. The benefits may well outweigh this risk; if you are among those who gain much you can always stop. But there are also alternative treatments including counseling, 5-htp, same, st john's wort ; homeopathy; consider seeing a holistic md or nd to explore all options. ...Read more

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I am on 100mg Zoloft (sertraline) and have gained a lot of weight over several years. Is this a side effect?

I am on 100mg Zoloft (sertraline) and have gained a lot of weight over several years.  Is this a side effect?

Side effects: Weight gain is a potential side effect for any psychotropic medication. Some agents more pronounced than others. Dietary attentiveness, exercise and review of all meds. Used may decrease this issue. Careful balance is prudent between risks & benefits, and should be reviewed periodically during the course of care. ...Read more

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Dr. gave me zoloft 25 mg. In your experience, do most gain, lose or stay the same weight using this. He told me its neutral but i have BDD and worry?

No Weight gain: Actually Anorexia is one of the AE of ZOLOFT the top 5 Adverse effects are Diarrhea, Nausea, Headache, Insomnia, dizziness. AE of Weight gain in my opinion is insignificant. hope that helps Now you may start feeling good less depressed which in itself my be an appetite stimulant. Beware! ...Read more

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How does Zoloft (sertraline) lead weight gain?

How does Zoloft (sertraline) lead weight gain?

Not really known: 4.5% people treated with zoloft (sertraline) had a significant weight gain in one study. Weight gain is more likely if the person is taking zoloft (sertraline) for 6 months or longer. There are some people who experience increased carbohydrate craving on zoloft (sertraline). However, mechanism for weight gain is not well understood. ...Read more

Dr. Alan Ali
991 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more