Doctor insights on:
Does Benadryl Cause Drowsiness
Enters the brain: The molecular structure of benedryl allows it to enter the brain where it can interfere with the chemicals that transfer messages between brain cells. In most people it causes drowsiness, in some it will cause the opposite. Newer antihistamines like loritadine & fexofinadine have molecular structures that prevent entry into the brain, so they don't make you drousy. ...Read more
What can I do, besides taking benadryl, (diphenhydramine) to treat hives. Ate something that caused my body to break out in hives. Don't want to go to work drowsy. Help!
What causes paradoxical reactions to benadryl (diphenhydramine). What mechanism ocurrs in the brain that makes the person stimulated rather than drowsy?
Besides doxylamine & diphenhydramine, what other OTC antihistamines cause drowsiness? Without a prescription.
Allegra (fexofenadine): All antihistamines especially the first generation ones (benadryl, bromchlorpheniramine, CTM) can cause drowsiness when given in sufficient doses. Zyrtec (cetirizine) at the recommended dose and Loratadine at 2x the recommended dose can cause drowsiness in some people. The least likely AH to cause drowsiness is fexofenadine (Allegra). ...Read more
Common effect: Benedryl is one of the most common products in over the counter sleep aids. It works quickly & well for allergies, but if you read the small print on most bottles it warns you of this effect. Occasionally some people get the opposite effect & get hyper on it, but that is far less common than the sedation. It actually enters your brain & messes with the neuro-transmitters. ...Read more
Four to six hours: The half life of Benadryl (diphenhydramine) is about four to six hours and usually the sedation will wear off within that time frame. As one continues to use it often a certain amount of tolerance develops and less sedation is appreciated. Studies have shown that its effect on brain function still continues despite less sedation. ...Read more
Please let me know if there is anything that contains the same ingredients that Benadryl (diphenhydramine) has but its non drowsy?
Antihistamine: Benadryl (diphenhydramine) is the first generation antihistamine that has anticholinergic property and crosses the blood-brain barrier causing drowsiness. Several other second generation antihistamine works well and does not cause drowsiness like zyrtec, allergra and claritin. ...Read more
Benadryl (diphenhydramine): Most people it will last 8 hours or so but I have seen people who still feel groggy 12 hours later or more ...Read more
A few hours: Benadryl (diphenhydramine) is a short-acting medication, so I would expect it to go away within 4-6 hours in most people, although some people are just in general a lot more sensitive to it and experience drowsiness for a longer period. If you're having problems, you might get tablets or liquid and try taking half of what you usually take (half a tab or 1 tsp of liquid is 12.5 mg instead of 25 mg in a whole tab/cap. ...Read more
I took 1 25mg benadryl (diphenhydramine) nd I feel the effect but if I take 2 it makes me to drowsy I wanted to know if I can take half of 1?
Of course: Everyone responds to things differently. There is no "perfect" dose for everyone. Don't take a dose of anything that makes you feel worse. Adjust the dose to what works for you. Take the lowest effective dose. ...Read more
Someone told me to take Benadryl (diphenhydramine) for the itching but is it safe to takr with all the other meds. Am on that makes. Me drowsy?
Benadryl (diphenhydramine) makes me drowsy. If I take the recommended dose of Benadryl (diphenhydramine) allergy ultratabs (25mg) for my flight will that be okay?
Benadryl (diphenhydramine) for my three kids 8 9 and 4 when will they start to feel the effect of drowsiness. I will be giving them Benadryl (diphenhydramine) on the plane to help sleep?
Benedryl: Sedation will typically start 20-30 minutes after the dose. If giving a weight appropriate dose, it should be safe to give prior to the flight. However, some children have a paradoxical reaction to antihistamines, causing them to be hyperactive. You might want to think about that if you've never given your child Benedryl before. Have a great flight! ...Read more
No it does not: No there is not enough absorption to make you drowsy unless used in very large body surface area. ...Read more
If I take two tablets of Benadryl, (diphenhydramine) and two tablets of velerian root, will it just produce drowsiness? It won't harm / kill me?
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I took one benadryl (diphenhydramine) pill. Its been 8 hrs and I'm just now feeling very dizzy and drowsy. I don't normally get any side affects. How can I get rid of it?
Wait: You have to wait till effect of medicine wears out. There is nothing additional you need to do ...Read more
Can I take benadryl, (diphenhydramine) buspirone, and sertraline together? Before bed? I know it will probably increase drowsiness, I just want to make sure it's safe.
Not a good idea: It is usually not a good idea to take several medications with similar (but not identical) actions without a doctor's supervision. One may get away with it, but then why take a chance? ...Read more
If I become resistant to effects of diphenhydramine drowsiness, can I switch to doxylamine, or am I resistant to that too since they're similar drugs?
How long does diphenhydramine stay in your system? I took 100mg before sleep, but 12 hours later, I'm still drowsy. The more dosage, the longer?
Takes a while: It sounds like it is still in your system. The half life varies quite a bit from person to person although some sources will describe a half life of around seven hours. That means that seven hours later you can still have half of the medicine in your body. As you can see, you are probably going to need more time to clear it. Stay safe! ...Read more
Hangover: So this depends on a lot of things. Typically I tell people between 12-18 hours if they are overall healthy (remember it is a medication that could be dosed every 6 hours!). Realistically may be more like 24+ hours especially if other medications are being used or someone is older. ...Read more
How many minutes does it take for diphenhydramine to kick in? Please answer for these categories: itch, sleepiness, empty stomach, with food
Less than an hour: It all depends on gastric absorption, but should be effective within 45 minutes. ...Read more
Yes but: A decongestant is often added to antihistamine and would counteract some of the drowsy effects but that is not a good solution. There are at least two other non-drowsy antihistamines available and steroid nasal spray actually works far better without the drowsy effect. If your only choice is a sedating antihistamine, take it an hour before you go to bed instead of the morning. ...Read more
Complex: Histamine is a wake promoting neurotransmitter in the brain. Older antihistamines like Benadryl (diphenhydramine) cross into the brain and block this center allowing for drowsiness to occur. The newer antihistamines like alleges, claritin, zyrtec do not cross as easily and are less likely to promote drowsiness. ...Read more
Cross into brain: Older antihistamines, such as diphenhydramine, or chlorpheniramine, actually cross the barrier between the bloodstream and the brain. This causes many people to feel drowsy or sedated. It can make some people irritable, or even cause insomnia. For this reason, the "non-sedating" antihistamines were developed. These medications cause much less drowsiness, and are better tolerated. ...Read more
Typically about four: Hours, but that depends on how much one has taken, and let's face it, we all have different rates of metabolism. ...Read more
Bitten by unknown insect. Redness and swelling to forarm. Marked with pen and doubled in size over 36hrs. Taking non drowsy antihistamines and icing?
Ice: Benadryl (or your choice of a non-sedating antihistamine such as Zyrtec, Claritin, or Allegra), ice, and ibuprofen is a good initial treatment for insect bites. Infection is a possible delayed complication. If you develop a boil, a discolored blister, fever, increasing pain, or other concerning signs, see a physician for an exam. ...Read more
Do histamines (not antihistamine medications) make you drowsy? Antihistamines (no decongestants added) seem to make me more alert when allergies flare
Yes: Histamine is a substance released during an allergic attack and can cause drowsiness. Some of the older generation anti-histamine agents (like benedryl) can cause drowsiness because they can pass the "blood brain" barrier and cause a direct effect on thinking. In rare cases in adults, antihistamines can cause agitation. ...Read more
I have a rash and it itches. I think it's an allergy. Instead of taking bendryl, would Allegra (fexofenadine) work just as well? Trying to avoid drowsiness.
What otc medication is best for allergies?? Currently taking benedryl but it makes me too drowsy. My current symptom is just constant running nose, no other symptoms.
Zyrtec (cetirizine) makes me very drowsy. Is this common and are there non-drowsy antihistamines that provide as effective allergy relief? Thanks
Yes: This is a common side effect of Zyrtec, but it is different for everyone. If Zyrtec makes you drowsy, you could try the other 2 common anti-histamines instead - Allegra or Claritin (loratadine). Some people have been drowsy with these medicines as well, but others have not. Best wishes. ...Read more
I am sneezing, feeling weeuk, congested nose and tiered. No fever and its third day. Took benedryl for but it makes me too drowsy. What should I do?
Rest and Hydration: Most likely a viral upper respiratory tract infection with increased congestion and fatigue. These can last for days to over a week and are often not associated with fevers. Symptomatic management is key with lots of hydration, rest, and NSAIDs for any headaches or pain. If these symptoms are recurrent or seasonal in nature you could be suffering from allergies and likely require Allergy workup. ...Read more
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