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Doctor insights on: Does Antiphospholipid Antibody Cause Preeclampsia

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I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?

I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?

Probably safe: Per Uptodate Oral contraceptives containing low levels of estrogen are probably safe in patients with mild well-controlled SLE. Avoid use in pts with with increased risks of clotting. Patients with anti phospholipid antibodies, nephrotic syndrome, hx of thrombophlebitis, CAD, migraines, smokers. uncontrolled HTN. Of course weigh the risks and benefits with your personal Doctor. ...Read more

Dr. Arthur Balin
27 doctors shared insights

Antiphospholipid Antibody (Definition)

Antiphospholipid syndrome (APS) is a disorder of blood coagulation related to the presence of autoantibodies called lupus anticoagulant and anticardiolipin. APS can cause blood clots, which most often occur in the deep veins of the legs, a condition called deep vein thrombosis. Blood clots can increase the risk for stroke and pulmonary embolism (clots in the lungs). Patients with APS are also at high risk for pregnancy complications, including miscarriage ...Read more


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How does antiphospholipid antibody syndrome cause miscarriage?

How does antiphospholipid antibody syndrome cause miscarriage?

Autoimmune: Apl syndrome is an autoimmune disease in the same general catagory as lupus. It causes abnormal blood clotting , and attacks the body to disrupt normal funtion. Not only does it affect early pregnancy but women's spllens have been removed during a pregnancy to try to keep from pg loss. You need expert maternal-fetal doctor care before and during the pg! ...Read more

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What type of hematological malignancy itself would cause elevation in Antiphospholipid antibody ( aPL ) ?

What type of hematological malignancy itself  would cause elevation in Antiphospholipid antibody  ( aPL ) ?

None: APL is more related to autoimmune disorders which may involve various target organs in the body but not to malignancy. Not all patients with this antibody become ill. You need to consult a rheumatologist if you are having symptoms. ...Read more

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31 y/o female. My CRP is 13.1 and I have antiphospholipid antibody syndrome. I am concerned that the combination of the 2 is going to cause death. I already take 10mg of coumadin (warfarin). What else to do?

31 y/o female. My CRP is 13.1 and I have antiphospholipid antibody syndrome.  I am  concerned that the combination of the 2 is going to cause death. I already take 10mg of coumadin (warfarin). What else to do?

Slow down: CRP can be a sign of inflammation from anything including a cold, but it isnt considered so dire without a some kind of major diagnosis being made. And for the apla the main thing is to prevent blood clots which you are doing, and unfortunately the risk of miscarriages. ...Read more

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Does antiphospholipid antibody syndrome cause weakness and fatigue?

Does antiphospholipid antibody syndrome cause weakness and fatigue?

Yes: Yes it can cause vasculicitis and cause decrease in blood flow. It can predisposed to stroke. ...Read more

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I am on warfarin due to aps or antiphospholipid antibody syndrome. My lupus caused aps. Can i take phentermine?

I am on warfarin due to aps or antiphospholipid antibody syndrome. My lupus caused aps. Can i take phentermine?

See a neurologist: I wish there was an easy yes/no answer to this. APS makes you prone to clots and catastrophic APS can cause multi-organ failure. Unfortunately phentermine is a stimulant that can cause blood vessel narrowing. I would make this decision in conjunction with an endocrinologist and neurologist. ...Read more

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Could you explain what is antiphospholipid antibody test?

Could you explain what is antiphospholipid antibody test?

Auto-antibody: Antiphospholipid antibodies affect clotting of blood and cause clots to form in blood vessels. There is more than one type of test for these, one is a type of test for syphilis and others test for effects on clotting. See this site for more info. http://www.mayoclinic.com/health/antiphospholipid-syndrome/ds00921. ...Read more

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How many pregnant women suffer from antiphospholipid antibody syndrome, and what is the expectancy for pregnancy outcome?

How many pregnant women suffer from antiphospholipid antibody syndrome, and what is the expectancy for pregnancy outcome?

Not common: People with this genetic disorder seem to have a higher number of miscarriages, which is what usually inspires testing for it. We treat these patients with aspirin, sometimes blood thinners and sometimes steroids. There is greater risk for prematurity and small fetuses, but under treatment, most will have successful outcomes. ...Read more

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I've had abnormal and worsening labs for 4yrs w/ increasing ANA to 1:640, homo pattern & antiphospholipid antibody, now all labs are perfect;how/why?

I've had abnormal and worsening labs for 4yrs w/ increasing ANA to 1:640, homo pattern & antiphospholipid antibody, now all labs are perfect;how/why?

Bad lab: A neg. Test when others are positive may be a lab error. These tests are difficult to perform and some of the lab methods are poor quality. Whether the test is negative or positive has no meaning if you have no symptoms. Don't get hung up on a lab result. There are many people who have had positive tests like yours with no illness. The more important issue is do you have any signs of disease. ...Read more

Dr. Nikolaos Zacharias
226 doctors shared insights

Toxemia (Definition)

Toxemia, is an old term for pre-eclampsia, is a condition consisting of high blood pressure and protein in the urine that can occur during the second half of pregnancy. If untreated this can lead to a life-threatening ...Read more


Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more