Doctor insights on:
Does Antiphospholipid Antibody Cause Preeclampsia
Autoimmune: Apl syndrome is an autoimmune disease in the same general catagory as lupus. It causes abnormal blood clotting , and attacks the body to disrupt normal funtion. Not only does it affect early pregnancy but women's spllens have been removed during a pregnancy to try to keep from pg loss. You need expert maternal-fetal doctor care before and during the pg! ...Read more
Antiphospholipid syndrome (APS) is a disorder of blood coagulation related to the presence of autoantibodies called lupus anticoagulant and anticardiolipin. APS can cause blood clots, which most often occur in the deep veins of the legs, a condition called deep vein thrombosis. Blood clots can increase the risk for stroke and pulmonary embolism (clots in the lungs). Patients with APS are also at high risk for pregnancy complications, including miscarriage ...Read more
When testing for Antiphospolipid Antibody Syndrome, does taking baby aspirin affect the Lupus Anticoagulant (PTT-LA, dRVVT) test results?
Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, and are usually treated with Heparin injections and Aspirin during pregnancy. ...Read more
No: Pih includes both gestational hypertension, which is a benign condition where the woman's blood pressure increases slightly without the associated proteinuria, edema or lab abnormalities found in pre-eclampsia. Hellp syndrome is a variant of severe pre-eclampsia characterized by hemolysis, elevated liver enzymes and low-platelets. Blood pressure may be high as well. ...Read moreSee 1 more doctor answer
Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read moreSee 1 more doctor answer
Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?
Anitphopholipid: It can be a part of a genetic or autoimmune disorder such as lupus. ...Read more
Misconception: It is a misconception that erythroblastosis fetalis can only occur in rh negative moms who carry a Rh pos baby. Mom can develop antibodies against a variety of other components of the human blood system that can cause erythroblastosis in the baby - fortunately these conditions are rare. ...Read more
Yes: Monoclonal antibodies are important as medications and diagnostic tools, but if you are making a very large amount of one antibody, it's concerning for plasma cell myeloma. A small spike without other signs of trouble is "monoclonal gammopathy of uncertain significance" and is a small risk for trouble in years or decades. Find out what's up & i wish you luck. ...Read more
ABO Type&Screen, does "negative" antibodies mean NO antibodies at all or no UNexpected antibodies for the reported blood type?
No unexpected ones: It means no antibodies against the red cells of the cross match. E.g., if you have type A blood, you would have anti-B antibodies as a matter of course. The potential donor blood is type A, but you also have no antibodies against any of the other antigens (outside of ABO system) which mY be found on red blood cells. ...Read more
Lupus and pregnanacy: Sle or lupus is less likely to cause serious problems in pregnanacy if the disease is well controlled before conception, especially if you are cared for by both a rheumatologist and "high risk" ob. Also presence of lupus anticoagulant can be managed suceesfully. ...Read moreSee 1 more doctor answer
Specific to patient: The test by itself is not diagnostic.. It depends on your evaluation, examination, clinical factors are the most pertinent. The lab reports are guidelines but not diagnostic in themselves. ...Read more
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