Top
10
Doctor insights on: Does Alpha Thalassemia Causes Leukemia

Share
1

1
Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

See 1 more doctor answer
Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


3

3
Does alpha thalassemia cause pvcs?

Probably not: Alpha thalassemia probably doesn't cause pvc's (premature ventricular beats, a type of extra heartbeat). However, some thalassemia patients have magnesium deficiency, which can make pvc's more likely to occur. Patients who get transfusions off and on may be drinking lots of coffee, using caffeine or phenols in coffee to decrease iron absorption, to hold off iron overload. Caffeine can cause pvc's. ...Read more

See 1 more doctor answer
4

4
What is alpha thalassemia disorder?

What is alpha thalassemia disorder?

Hemoglobin problem: Alpha thal is caused by mutations that effect the production of a part of the hemoglobin molecule (Alpha chain). There are 4 genes involved in this production. Mutations can occur in 1 to 4 of these genes. The disease is more problematic the more genes are mutated. This disease is inherited from parents. ...Read more

7

7
Will there be immunocompromise with alpha thalassemia?

Not directly.: Thalassemia affects red cells while immunity is related to white cells. However, with severe thalassemia, life-saving treatment may cause immunocompromise as a side effect. ...Read more

See 2 more doctor answers
8

8
Can an alpha thalassemia carrier marry a beta thalassemia carrier?

Of course you can: A person can marry anyone they like. From a thalassemia perspective, and assuming your Alpha thal trait is in cis, your child has a 50/50 chance of being Alpha thal trait vs. Normal and a 50/50 chance of being beta thal trait vs. Normal. Given there is consideration of inheriting two distinct trait states, it would be prudent to sit with a genetic counselor to understand the implications clearly. ...Read more

9

9
Is it possible to have both alpha thalassemia and beta thalassemia?

Is it possible to have both alpha thalassemia and beta thalassemia?

Traits, yes: Because the Alpha and beta thalassemia gene mutations are common, it is possible for a baby to inherit one from mom and another from dad. The child could be "trait" in both Alpha and beta, or less likely, be "disease" in one and "trait" in the other. It is hard to imagine being "disease" in both and still survive. ...Read more

See 1 more doctor answer
Dr. Milton Alvis Jr
30 doctors shared insights

Hemoglobin H Disease (Definition)

Hemoglobin H disease (alpha thalassemia) is a blood disease where one of the molecules that helps carry oxygen in the blood cell is missing. This causes a ...Read more


Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more