Doctor insights on:
Does Acetylcholine Have Anything To Do With How Vision Works
Yes, in a way.: Acetylcholine transmits signals from nerves to muscles, such as those that control the pupil size and the focusing power. When these muscles are activated, the pupil will get smaller and the focusing muscles will contract, enabling the eye to see up close, as for reading. These two actions can also normally occur separately. Acetylcholine is sometimes used during eye surgery. ...Read more
Yes: Acetylcholine is a neurotransmitter. It behaves like a key activiting receptors "keyhole" diseases like myasthenia gravis affect the receptor "keyhole". Acetylcholine in its pure form only used inside the eye to constrict the pupil after cataract surgery. Other drugs that mimic its behavior include pilocarpine. Pilocarpine makes pupil smaller and your vision blurry. Great question. ...Read more
Consult Neurologist!: Complex answer depending on exact levels of deficiency of these vitally important neurologic "neurotransmitters" chemicals that control specific brain and muscle functioning. Multiple diseases such as depression and neurologic or muscle disorders may result from dramatically abnormal high or low levels of these chemicals in the body/central nervous system. ...Read more
widely used at synapses in the peripheral nervous system. Released at the terminals of
all motor neurons activating skeletal muscle.
All preganglionic neurons of the autonomic nervous system,
the postganglionic neurons of the parasympathetic branch of the autonomic nervous system.
Serotonin is a neurotransmitter where it mediates gut movements ...Read more
Different things: Agonists stimulate receptors while antagonists inhibit them. Most often we use the antagonist drugs in treating different diseases. However, those conditions that decrease sputum, sweat or tear production are sometimes treated with an agonist. Pilocarpine (an agonist) is used to treat glaucoma but by a different mechanism as mentioned above. ...Read more
I'm not sure what you mean by this deficiency, and don't know about alternative treatments. This site is intended mostly for main stream physicians.
I believe you should consult with your primary care physician, review whatever symptoms you believe are related to this, get the appropriate lab tests, and develop an accurate diagnosis first. ...Read more
Neuromusculat ransmi: Acetylcholine is an import neuromuscular transmitter that controls muscle functions and bodily and organ movements inside. So using antagonists can block these processes and cause trouble especially with the function of our smooth muscles of the bowel (constipation)bladder (urine retention) and eyes (blurred vision). ...Read more
What are the effects of too high/too low acetylcholine levels on the muscle during swimming practice?
ACH synthesis brain: Ach in the brain is produced from acetyl-coa (from glucose metabolism) & from choline, which is actively transported across blood-brain barrier. Most dietary choline comes from phosphatidyl choline (major phospholipid in membranes of plants&animals) acetyl-coa & choline are independently synthesized in neuron cell body & transported along axon to synapse where they are joined into acetylcholine. ...Read more
Think yours are low?: This is about the nervous system. What makes you think your "levels" are low? Neurotransmitters don't HAVE "levels". They don't just float around or circulate in blood. They're made in the terminal boutons of neurons, released into the synaptic cleft, & immediately either recycled & replaced or taken back up. Neurochemistry isn't just a New Age fad. REAL knowledge is power. Go arm yourself. ...Read more
If I have acetylcholine deficiency will be able to lift weights as much as a normal person can? What if I have higher acetylcholine will I be able to lift more than a normal person?
My thoughts: Not clear what you really want. Acetylcholine does mediate neuromuscular transmission, and if malfunctioning, due to diseases, such as myasthenia, spider bites, botulism, fertilizer sprays. Level drops in brain due to alzheimers, but does not affect muscle. Not sure whether you are asking about supplements for muscle growth, but this does not involve ach. ...Read more
What are the effects of prolonged anxiety and anger on acetylcholine, serotonin, dopamine levels?
Negative emotions: Strongly impact our biochemistry in general. They can eventually burn out our adrenal glands. For a lab analysis of neurotransmitters via urine your doc can use neuroscience lab, who specialize in this, along with supplemental formulas to balance things naurally. Peace and good health. ...Read more
ACH effect on BV: M3 muscarinic ach receptors are located in smooth muscles of blood vessels. Because they're gq-coupled & mediate increase in intracellular calcium, they typically cause contraction of smooth muscle (as in bronchi). But activation of m3 on vascular endothelial cells causes increased synthesis of nitric oxide, which diffuses to adjacent vascular smooth muscle cells and causes their relaxation. ...Read more
The simple answer is yes!
There are a number of articles about this on the web, many of which would be hard to understand, but some should make sense. ...Read more
Can the long term of smoking cigarettes cause an imbalance of the neurotransmitter Acetylcholine?
Avoid cigarettes: Tobacco smoking causes so many dangerous effects on the body, that it is only its extreme addictive properties that keep sensible people to still smoke. It certainly could affect the neurosensory pathways that include acetylcholine. Good time to stop this seriously dangerous activity (smoking). ...Read more
Would acetylcholine supplementation alleviate the drowsiness I experience when I take Desloratadine? If not, then what can I do?
NO: Try regular loratidine: a non-sedating antihistamineGet a more detailed answer ›
If acetylcholinesterase is not present to remove acetylcholine, the muscle is in contraction. What is the name of the disorder/disease?
I failed my qsart test what is the next step and what could this mean? Acetylcholine receptor ab 0.00 nmol/l <=0.02 12/12/2012 and my antibody norma
Quantitative sudomotor autonomic reflex testing (qsart) is used to diagnose:
painful small fiber neuropathy when nerve conduction test results are normal; disturbances of the autonomic nervous system, which controls the sweat glands, heart, gastrointestinal tract, other organs, and blood pressure; complex regional pain syndrome or reflex sympathetic dystrophy.
A discussion with ur neurologist next. ...Read more
I’ve read that anticholinergic drugs block acetylcholine, causing mental deterioration. Is this a concern if you're not eldery? Taking amitriptyline 25
Minimal concern: Correct. Amitriptylline has anticholinergic properties. It's been around for many years and is a very useful drug for a variety of medical problems and also relatively inexpensive. 25 mg is a low and well tolerated dose. Cognitive changes in the elderly a concern given age-related mental decline, other diseases, and the fact that they are often on other meds with anticholinergic effects- additive. ...Read more
Can raising acetylcholine levels through supplements lead to insomnia? When acetylcholine is raised does that also raise dopamine too?
Tested for acetylcholine receptor ab panel; both binding and blocking were 0, but modulating came back at 10. Does this mean I have myasthenia gravis?
AchRAntibodies: Binding antibodies are the most sensitive--they are positive in over 80% of ms patients. Blocking antibodies are positive in about half. Modulating antibodies alone don't support the diagnosis and have a lot oof false positives. In summary the achreceptor antibody panel does not suggest that ou have ms>. ...Read more
I read that anticholinergic drugs block acetylcholine, causing mental deterioration. Is this a worry if you're not elderly? I'm taking amitriptyline 25mg
Yes, since: Acetylcholine is the preganglionic transmitterGet a more detailed answer ›
No: I cant explain any direct effect of trauma to an end organ like the penis directly on the brain. There may be some psychological after-effect, but not a direct effect. ...Read more
Avoid Interactions: The occurance of interactions between Acetyl Carnitine and Zyprexa are rare but present. I would avoid the use of these two together. There have been rare cases of psychosis with the use of both. Please consult with your primary doctor or psychiatrist if you would like to continue. ...Read more
Why does acetylcholine, an inhibitory neurotransmitter, cause the adrenal glands to release stimulatory hormones?
Not correct: Hi. Acetyl choline (ACh) is not an inhibitory neurotransmitter. The sympathetic nervous system uses ACh as the neurotransmitter in the sympathetic ganglia (the 1st synapse outside the CNS). Usually that's from one neuron to another, but in the adrenal medulla, the cells are really the second neuron, but they release their contents (catecholamines) into the blood, not onto an organ (like the heart) ...Read more
What other diseases can give the same symptoms as systemic myasthenia gravis when antibodies against the acetylcholine receptor are negative?
Why do people having eye surgery have to have their eyes constricted (such as, by use of acetylcholine)?
Atropine dilation: A dilated exam is important before cataract surgery to make sure there are no diseases in the back of the eye. For example diabetic reitna problems, glaucoma, or macular degeneration. There is no need to constrict eyes except if having laser for narrow angle glaucoma. ...Read more
Can supplementing with acetyl L- Carnitine raise acetylcholine all over the body or does it only affect ACh levels in the brain?
Probably neither: Unless you were severely deficient of it previously, supplementing with it is getting peed out in your urine. This supplement is like many on the market right now- they promise you all kinds of things they can't back up - and don't have to because they are classified as foods, not as medicines. So show me a good study that someone of normal diet and health actually increases brain levels with this ...Read more
Can acetylcholine supplement be taken while on adderall (dextroamphetamine and racemic amphetamine) or any CNS stimulant?
Discuss w/ Dr: The Dr who prescribed the Adderall (dextroamphetamine and racemic amphetamine) needs to know about any other things you take or plan to take. You are right to note the importance. You need to work w/ the Dr so they know what to do. It's a big part of good Tx. And part of what the service includes.. ...Read more
None: Giving precursors of acetylcholine, that would provide choline, is not effective in prevention or treatment of alzheimer's disease. ...Read more
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