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Doctor insights on: Does A Negative Parr Result Rule Out Lymphoma

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Does a negative parr result rule out lymphoma?

Does a negative parr result rule out lymphoma?

No?: Polymerase chain reaction (pcr) for antigen receptor rearrangements (parr) is not a test i would necessarily consider in initial lymphoma diagnosis. Lymphoma is diagnosed (ideally) by an excisional (not just needle) biopsy and/or bone marrow biopsy. There are many additional tests including molecular (eg, pcr) tests that can be used to further subclassify diagnosis. ...Read more

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Dr. Michael Thompson
1,724 doctors shared insights

Lymphoma (Definition)

Lymphoma is cancer of the lymph system, which is an infection fighting collection of nodes of lymph tissue populated by white blood cells and ducts that drain excess fluid. The system ...Read more


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Would a negative ANA rule out lymphoma? Does lymphoma cause a positive ANA test result?

Would a negative ANA rule out lymphoma? Does lymphoma cause a positive ANA test result?

It does not: At your age, if you have lymphoma it's probably Hodgkin's. ANA really has nothing to do with malignant lymphoma. If you're worried about big lymph nodest, trust me -- lymphoma nodes are obviously very abnormal. Best wishes, and I hope you'll always stay actively involved with your health. ...Read more

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Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?

Can 2 biopsies done at same time rule out cutaneous t-cell lymphoma completely? If symptoms point to ctcl but biopsy was neg when should we re-biopsy?

Not Completely: The average number of biopsies to completely diagnose CTCL is about 6. That said, if the type of CTCL is the common type, mycosis fungoides(MF), and not mimics of MF, then 1 or 2 biopsies could be diagnostic especially if typical patches, plaques of CTCL. If the latter, ancillary tests including molecular clonality T cell test are crucial for diagnosis excluding mimics. Rebiopsy in about 3 mos. ...Read more

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Diagnosis. B.Cell non hodgkin, s lymphoma favor burkitt, s lymphoma. This us the result of biopsy taken during appendicectomy. D20 positive and tdt neg?

Diagnosis. B.Cell non hodgkin, s lymphoma favor burkitt, s lymphoma. This us the result of biopsy taken during appendicectomy. D20 positive and tdt neg?

CD20 is a B-Cell: Marker hence the assignment of a b-cell nhl. Tdt is an immunohistochemical stain used to classify blood cells. Burkitt's is a very aggressive process -- get started on a plan with a hematologist straight away. ...Read more

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Lymph node removed n biopsy result states "no definite evidence of lymphoma. Advised follow up to rule ojr hodgkins disease.Is it a problem?

Lymph node removed n biopsy result states "no definite evidence of lymphoma. Advised follow up to rule ojr hodgkins disease.Is it a problem?

May be: The pathology report has contradictory information. You should discuss it with your doctor to consider having a hematopathologist review the biopsy slides for a second opinion. ...Read more

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If tested for lymphoma previously and came up negative before due to having an aunt pass because of it could you still have a chance to develop it?

Why do you ask?: You're 23 years old. Your risk for lymphoma is very low; the highest risk is Hodgkin's which is usually curable nowadays. A person can develop lymphoma at any age, but it's not very likely. If you have fever, weight loss, or night sweats, look for some other case -- TB, endocarditis, other possible causes. ...Read more

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Please tell me, could my blood results mean lukiemia or lymphoma?

Please tell me, could my blood results mean lukiemia or lymphoma?

Hard to say...: Without knowing exactly what those results are, it is impossible to tell. Leukemia can be frequently diagnosed based on examination of the blood, lymphoma not so often. Please ask your physician to interpret the results of your blood tests for an adequate diagnosis. ...Read more

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Fnac report negative, but biopsy shows burkins lymphoma.Is it possible?Why?

Sampling error: Fine needle aspirate of lymph nodes are not ideal for ruling out abnormal findings. Especially, with lymphomas there may be areas within the ln that are not involved and sampling of these areas may be misleading. Excisional biopsy is the gold standard, as it allows for assessment of individual cells and architecture of lymph node and adequate tissue for specialty workup. ...Read more

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Can lymphoma be diagnosed with biopsy of lymphnodes? If so how long does it take to get results?

Yes: Biopsy of lymph nodes is a standard procedure to rule out lymphoma. Pathology reports usually come back to the physician within several days, but it can depend on the lab and the quality of the biopsy. One week is a reasonable expectation. ...Read more

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