Top
20
Doctor insights on: Doctors On Drug Induced Lupus

Share
Dr. Emily Altman
26 doctors shared insights

Drug Induced Lupus (Definition)

There are major differences between what I call while lupus and drug-induced lupus. Basically these are illnesses with some similar manifestations and clinical manifestations. Some of the manifestations like rashes and joint pain can occur in both, but kidney involvement is notfound with drug-induced lupus. There are other differences also but this is one of the ...Read more


2

2
Heard of drug induced autoimmune hepatitis?

Heard of drug induced autoimmune hepatitis?

Yes: Many drugs can induce autoimmune type phenomena, to include hepatitis. ...Read more

3

3
Can anyone comment on the drug pacerone (amiodarone)?

Can anyone comment on the drug pacerone (amiodarone)?

PACERONE (amiodarone): Yes it is available under generic name of amiodarone by doctors order by prescription only.It is also available as pacerone, brand name.It is used to treat and prevent ventrcular tachycardia which is a serious and life threatening arrythmia. ...Read more

4

4
Can diabetes medicine cause false positive on a drug test?

Can diabetes medicine cause false positive on a drug test?

False positive?: What are you looking for? No diabetic medicines will not cause a false positive ...Read more

5

5
My doctor put me on minocin (minocycline) for my acne but i'm nervous of side effects and drug induced lupus. Are these very rare? I've been on this drug years ago.

My doctor put me on minocin (minocycline) for my acne but i'm nervous of side effects and drug induced lupus. Are these very rare? I've been on this drug years ago.

Good choice: Acne is a serious, chronic disease that is a major personal and professional liability. Minocycline very seldom causes problems and when it does, discontinuing the medicine and replacing it with something else is easy and you'll heal up fine. Nothing worthwhile in life is risk-free. ...Read more

See 1 more doctor answer
6

6
Shouldnt we avoid pharmacological treatment of drug induced liver disease?

Shouldnt we avoid pharmacological treatment of drug induced liver disease?

How ?????: Liver is a complex organ, most of the time protects itself by detoxifying chemicals rarely fails, . Remarkable progress has been made in control of infections, b.P. Stroke, cancer, vas dis meta.Diseases etc by use of medications, prolonging life and virtually every drug could be hepato toxic and unavoidable. Watchful fda withdrawn several ( duracet, ruzulin, pemolin etc ) may be more to go. ...Read more

See 1 more doctor answer
7

7
Prescribed plaquenil (hydroxychloroquine) for P.A.- mild psoriasis + other conditions+strong fam history, what are chances of severe psoriasis outbreak from drug? Thanks!

Prescribed plaquenil (hydroxychloroquine) for P.A.- mild psoriasis + other conditions+strong fam history, what are chances of severe psoriasis outbreak from drug? Thanks!

I am not sure what : P.A. is. I personally do not use plaquenil (hydroxychloroquine) for psoriasis as it has been link with causing flare or outbreak for psoriasis. I would recommend to choose other DMARDs or biological esp there are a lot of choices now. ...Read more

See 1 more doctor answer
8

8
+ANA test.elevated histones AB only. only on aspirin and BB. take some supplements in low doses like serrapeptase.can this cause drug induced lupus?

+ANA test.elevated histones AB only. only on aspirin and BB. take some supplements in low doses like serrapeptase.can this cause drug induced lupus?

Not known : I am not aware that this is associated with drug-induced lupus. Antihistone anybody's can be seen in wild or systemic lupus as well as drug-induced lupus. Certainly there is no evidence from what you tell us that you have lupus of any type. you say you're on aspirin and I'm uncertain why and you say are on BB and I don't know what that is. From the information you're giving us I'm not certain the information you're giving us I'm not even certain why they did it in a testing on you. From what I can tell you don't have Lucas from this conversation ...Read more

9

9
Does plaquenil (hydroxychloroquine) cause false positives on drug test?

Does plaquenil (hydroxychloroquine) cause false positives on drug test?

Only .01% have: That means that 1 in 10,000 people taking plaquenil (hydroxychloroquine) reported having a false positive result on a urine drug screen. If that happens to anyone w/ a Rx for it - I'll wager that it would be recognized as an error and no bad consequences would happen for the individual. Don't worry. Best! ...Read more

See 1 more doctor answer
10

10
Immunologist agreed I have malar rash. How is lupus dx'd since we can't rely on antibody or inflammatory tests w my immune deficiency and steroid tx?

Immunologist agreed I have malar rash.  How is lupus dx'd since we can't rely on antibody or inflammatory tests w my immune deficiency and steroid tx?

Management/workup: The initial workup will include renal function testing and tests for circulating antibodies. Your steroid treatment may affect the tests for inflammation, moreso than autoantibodies which are still detectable even while being treated with steroids. Avoiding and treating infections, including CMV will be part of the management. I hope that this helps. ...Read more

See 1 more doctor answer
12

12
If someone is misdiagnosed with sle & start using sle med (plaquenil, prednisone, imuran) will he get sle or any other disease?

If someone is misdiagnosed with sle & start using sle med (plaquenil, prednisone, imuran) will he get sle or any other disease?

No: A normal person who receives immunosuppressant lupus medications will not develop lupus. They can of course have the usual side effects that go with the medications, but they will not develop lupus if they didn't have it already. ...Read more

See 1 more doctor answer
13

13
7yrs on prednisone & methotrexate + for "resistant ra" recent elevated jo1, histone, muscle pain. How to confirm if polymyositis w/o stopping meds?

7yrs on prednisone & methotrexate + for "resistant ra"
recent elevated jo1, histone, muscle pain. How to confirm if polymyositis w/o stopping meds?

Mucle testing: Inflammatory myopathy, including polymyositis, is best diagnosed and treated by a trained rheumatologist. Symptoms are proximal muscle weakness. Abnormal lab tests include elevated muscle enzymes (CPK, AST/ALT); positive antibody tests, including Jo-1; abnormal EMG/nerve conduction test; edema seen on an MRI of proximal muscles; muscle biopsy showing destruction and regeneration of muscle cells. ...Read more

See 2 more doctor answers
14

14
R there any drugs for severe m.E? (i dislike drugs but uk nhs wont prescribe nutritiional/herbal/acupuncture type trtmnt on long tern basis..Only drug

R there any drugs for severe m.E? (i dislike drugs but uk nhs wont prescribe nutritiional/herbal/acupuncture type trtmnt on long tern basis..Only drug

Not exactly but: M.E. Is a diagnosis of exclusion. My experience is that most with it actually have chronic lyme with co-infections (but drugs are of limited help for that). Also, many are hypothyroid- even if their TSH is "normal" so thyroid hormone can help quite a bit. Many have intestinal parasites- not always easily diagnosed- many drugs can help these, but so can natural things like papaya seeds.See comment:. ...Read more

See 1 more doctor answer
16

16
Should people diagnosed with sle or discoid lupus avoid taking the drugs associated with drug-induced lupus?

Should people diagnosed with sle or discoid lupus avoid taking the drugs associated with drug-induced lupus?

If possible: Certain drugs can affect lupus so if there is a choice it may be prudent to avoid three drugs however depending on your circumstance there may not be other options. If you must take a drug associated with lupus be vigilant in reporting any joint pains, fever, or unusual symptoms to your doctor. ...Read more

See 1 more doctor answer
17

17
I'm on drug trial for toccilizumab with methotrexate, what to do about liver problems?

I'm on drug trial for toccilizumab with methotrexate, what to do about liver problems?

You will be monitore: Your will be monitored in the trial for liver problems. Each of these drugs methotrexate and tocilizumab can possibly cause liver problems. The trial protocol will decide about medication dose adjustment. You may have no liver problems with either of these. ...Read more

See 1 more doctor answer
18

18
Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it. ...Read more

19

19
Can clonazepam 1 mg show up dirty for any kind of drug on a 4 panel drug test that parole and probation use?

Can clonazepam 1 mg show up dirty for any kind of drug on a 4 panel drug test that parole and probation use?

Declare your Rx: In most jurisdictions patients are encouraged to take their prescribed medications, including clonazepam. As long as you have a current prescription in your name and are taking the medicine as prescribed, the safest course would be to notify the PO in advance that you are taking prescription medication. (be prepared to show proof.) going off meds you need is a much greater risk for most. ...Read more

20

20
I've lupus (sle), r.A., raynaud's syndrome, anemia, &hypertension. I take methotrexate, plaquenil, (hydroxychloroquine) Neurontin & lisinopril/hctz. I'm told i've decreased kidney function.Is that because of the medication?

I've lupus (sle), r.A., raynaud's syndrome, anemia, &hypertension. I take methotrexate, plaquenil, (hydroxychloroquine) Neurontin & lisinopril/hctz. I'm told i've decreased kidney function.Is that because of the medication?

Probably not: Lupus usually damages the kidneys and hypertension always does to some extent. Not all "decreased kidney function" picked up by today's lab screenings is real kidney damage -- any guy who lifts weights will get a warning from the creatinine from his muscles -- but i'd keep with your rx. Good luck -- this is a challenging disease. ...Read more

See 2 more doctor answers