Top 20 Doctor insights on: Do people who suffer from cystic fibrosis sweat more than regular people do
No: Patients with CF don't sweat more, but their sweat is more concentrated and will taste saltier. ...Read more
Extra loss: Cystic fibrosis is caused by a genetic mutation of cftr protein that moves chloride ions out of cells in respiratory tract, but into the cells in sweat gland ducts. Since cftr protein is not functional in CF pts, excess chloride gets secreted in their sweat, which causes the sweat to have higher salt concentration. That is why a sweat test measuring chloride is used as a diagnostic test for cf. ...Read more
CFTR: There is a defect in the sodium-chloride transporter encoded by the cftr gene results in an inability to appropriate consentrate saline in secretions (sweat, in the airway, in the pancrease) that are more viscous. ...Read more
Yes, Gold Standard: The gold standard for a diagnosis of CF is 2 back-to-back sweat chloride tests. However, the ability to run genetic tests and detect the disease in this fashion is becoming more common. In fact, it is now standard procedure in all 50 states for newborn babies to be screened, via blood from a heel prick, for cystic fibrosis. ...Read moreSee 2 more doctor answers
My son & wife tested neg for Cystic Fibrosis through screening test, not sweat test. However my son has hirschsprung disease. Should I test for CF - or it's high unlikely I have it? I'm 32. Feel fine
I wouldn't: There is no relationship between Hirschprung disease and CF. If you wand to know if you are an asymptomatic carrier of CF, the tests are available. However, you don't get to age 30 without symptoms when you have the disease and your fertility would also be diminished. If your wife is not a carrier, you can not produce babies with CF. ...Read moreSee 3 more doctor answers
Hi I suffer with cystic fibrosis and I also have MRSA in the lungs and I was wondering if it is possible that I can get tattoos..
Be cautious: Speak with your pulmonologist who is most familiar with your current status for clearance, but Pseudomonas colonization in the lungs should not usually prevent you from having procedures performed on your skin. You have listed MRSA as one of your conditions, which may put you at much higher risk for severe skin infection from a tattoo. ...Read more
Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US. A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications. Emotional & phys. Development depend on severity, time in hospital, complications. Morb. & mort. Factors afect emotional, cognitive behavior. ...Read more
Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read moreSee 1 more doctor answer
As a carrier:
Genetic carrier testing:
more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more
I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?
What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?
Acording to the CF foundation: the overall birth prevalence is 1/3700. It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000.
More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more
Equal: More than 10 million americans are unknowing, symptomless carriers of the defective cystic fibrosis gene. In order to develop cf, an individual must inherit a defective gene from each parent. Since the CF gene is not on a sex chromosome (x or y), males and females are equally affected. ...Read more
Not specifically: Most CF patients that are monitored and receiving regular healthcare can not be picked out in a crowd of people of similar age. If their disease were to go unrecognized and or untreated they would appear ill. ...Read more
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