Doctor insights on:
Do Brca1 And Brca2 Mutations Affect Men The Same Way They Affect Women
No: The penetrance of a mutation defines the risk of developing the disease in those that carry a particular mutation. Women with brca mutations have lifetime risks estimated between 40-80%; men's risks are much less-studied but are probably in the range of 10% or less. ...Read moreSee 1 more doctor answer
In genetics, a mutation is a change in the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. Mutations result from unrepaired damage to dna or to RNA genomes (typically caused by radiation or chemical mutagens), from errors in the process of replication, or from the insertion or deletion of segments of dna ...Read more
Cancer: Do men get breast cancer at the same rate of incidence as women during most of their lifetime?
No: no the breast cancer in men is significantly less prevalence than women. breast cancer does occur in men. In 2012 it was estimated that 2,190 new cases in males would develop, with 410 deaths. It tends to occur at a later age in men than in women, with the male peak age being 71 years old as opposed to peaks at 51 and 71 years old in women. Some men ignore breast lumps or think they are caused by an infection or some other reason and they do not get medical treatment until the mass has grown significantly. ...Read more
Can lifestyle affect genetic predisposition to get cancer? For example can healthy lifestyle decrease chance of cancer in jewish women
Yes: A healthy lifestyle (no tobacco, eating well, exercising) will reduce the risk of getting cancer in any person, jewish or not. Certain jewish and other ethnic groups have a higher risk than others (e.g. Ashkenazi jews and brca mutations) so gather as much family info as you can and discuss this with your doc. Live healthy please. Best regards. ...Read more
Can you tell me how the role of genes, alleles and proteins produce many different traits in twins?
Genetics class!: You have asked a very intelligent, but VERY complex question which cannot be adequately addressed in the scope of this forum. An entry level genetic course or book is recommended. ...Read more
Does the presence of multiple fibrodenomas in both breasts increases future risk of breast cancer?, and do they need to be surgically removed?
No: Fibroadenomas do not suggest an elevated risk for cancer, although they are likely to require biopsy in most cases to prove that. Typically, these biopsies can be done in a minimally invasive way. To learn more about breast biopsy options, please see http://www.Conciergeradiologist.Com/breast-biopsy.Html. ...Read moreSee 1 more doctor answer
Various ways: Sophisticated imaging studies of addicts in recovery showed gender differences in cues which may lead to relapse. For alcohol, women are more sensitive to harmful physical effects. They experience health complications at a younger age than men. Some addiction professionals describe a telescoping course of complications in female alcoholics. ...Read moreSee 1 more doctor answer
Women inherit their mothers body type but can also inherit the body of women on fathers side. Which is more common? Can you inherit from both sides?
Big gene pool: It is a big gene pool and some genes that you have do not necessarily manifest themselves. Any combination is possible. ...Read more
Does a homozygous gene mutation, e.g. 1p36.3, make me more likely to have other mutations in nearby genes on the same chromosome, e.g.1p34.1?
No: Gene mutations are still being researched and from my opinion, I don't think we're even close to scratching the surface of the miraculous human genome. That being said, mutations are a normal part of our evolution. Is therea reason you're concerned? If we know, you will likely get an answer sooner. ...Read more
Antiphysicotics raise prolactin & alter
dopamine in women, how else do they
affect a womans body negatively that
dr.'s don't tell?
Depends: The cost of genetic testing is a moving target these days as the costs of sequencing has come down substantially. Several companies are offering panels of clinically relevant genes including genes that increase risk of colon cancer such as the hnpcc genes. An example of a company is ambry genetics. A genetic counselor can help you research different panels and costs. ...Read moreSee 1 more doctor answer
If you have identical twins, will they both develop the same genetic/inherited disease at the same point?
Depends: If it's something that fully expresses itself with no modification (such as huntington's), yes. If it's going to express itself but is lifestyle-modifiable (type ii diabetes), timing will differ. The diseases for which there's a genetic component (diabetes, lupus, multiple sclerosis, many others) have only one twin affected more often than not -- you can find details. ...Read more
Why have instances of cancer, autism and gender defects become so prevalent in the last 50 years?
Likely environment: Environmental exposures starting in the womb and throughout our life can have an effects on our genetic makeup by causing very subtle changes in the expression of genes, some of which can be negative and others which may have no effect. Large scale exposures like Agent Orange are well documented but on a daily basis we all have the potential to be exposed to toxic exposures which are cumulative. ...Read more
I have extra genetic mutations for breast cancer & heart failure What's the likelihood that these genes will turn on & can I use diet to keep them off?
Complex genetics: Recommendations on gene mutations are best given by a medical geneticist, who needs a detailed understanding of the exact test that you had done and the detailed results. Many gene mutations cause a loss of function so you don't necessarily want to turn off the mutated gene. Modern genetics is discovering many genetic markers that convey only small risk of disease, and may require no treatment. ...Read more
What are some ways to reduce estrogen in males because I have gynocomastia and I've read estrogen influences male breast tissue. ?
See your doctor: True gynecomastia with breast tissue in males is rare. It can be a side effect of taking certain drugs or having a hormonal imbalance. I would see your doctor to make sure this is breast tissue and to check the chemical and hormonal balance in your body. You may also want to check your weight, as that is a more common cause of gynecomastia in males. ...Read more
Is breast cancer risk low for women in thirties? How does it compare to other cancers within this age group of women?Are other cancers just as common?
My parents are cousins. Why moles are in my body? Moles are due to hormone changes, glands, enviromental effects or particular protein found in genes?
Do cancer patients lose their hair from the chemo or the actual cancer? Also is it just women that lose their hair or men too?
This is a normal gene that makes a protein for basic cell functions. It was the second gene discovered that is often mutated in people at extra risk for breast cancer, and depending on the mutation these people often have increased risk of ovarian cancer as well. A person with a family history may be tested for the mutation and make ...Read more
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