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Doctor insights on: Do Both Parents Have To Be Cystic Fibrosis Carriers For A Child To Get It

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Do both parents have to be cystic fibrosis carriers for a child to get it?

Do both parents have to be cystic fibrosis carriers for a child to get it?

Yes: Cystic fibrosis is an autosomal recessive disease which means that a person needs to inherit 2 abnormal genes in order to have the disease. Those 2 abnormal copies come one each from the 2 parents, so both parents need to be at least carriers. ...Read more

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Dr. William Walsh
986 doctors shared insights

Cystic Fibrosis (Definition)

A genetic disorder of the lungs and digestive tract. It causes recurrent lung infections and inhibits growth in patients and average life expectancy of patients with cystic fibrosis ...Read more


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Do both parents have to be cystic fibrosis gene carriers for their child to get it?

Do both parents have to be cystic fibrosis gene carriers for their child to get it?

Yes: It is a recessive trait, so both have to have the gene to pass it to a child. ...Read more

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Do both parents have to be cystic fibrosis carriers in order for their child to be born with this disease?

Do both parents have to be cystic fibrosis carriers in order for their child to be born with this disease?

Yes: Both parents have to be carriers and then their child has 25% chance of having the disease, 50% chance of being a carrier and 25% of not even being a carrier. The most common mutation causing cystic fibrosis is ?f508. But there are over 1500 mutations identified so far. ...Read more

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If only one parent is a carrier of cystic fibrosis, how likely is the child to be a carrier?

If only one parent is a carrier of cystic fibrosis, how likely is the child to be a carrier?

50%: A carrier parent has 2 possible genes to pass along.There is a fifty % chance a child could get either the normal or CF gene. If they did, they would be a carrier, like the parent. ...Read more

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Does a child have to inherit the same mutation from both parents in order to have cystic fibrosis?

NO: Over 2, 000 mutations in the cftr gene are known which may cause cystic fibrosis. A child must inherit one mutation from each parent to have cystic fibrosis. ...Read more

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Does my child have to inherit the same exact mutation from both parents in order to develop cystic fibrosis?

Does my child have to inherit the same exact mutation from both parents in order to develop cystic fibrosis?

No: You need 2 mutations to inherit cf, but they can be, and often are, 2 different mutations. The type of mutation can have an impact on the severity of the disease and the child's prognosis. ...Read more

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Can you be a carrier of cystic fibrosis if you have two healthy parents?

Can you be a carrier of cystic fibrosis if you have two healthy parents?

Yes: Cystic fibrosis (CF) is a genetic disease, but it requires two faulty genes to be expressed as a disease. A healthy person can carry one defective CF gene and not be affected by cf. If each member of a couple has a defective CF gene, they have a 25% chance of having a child who inherits both defective copies of the CF gene. Depending on the type of CF gene defect, that child could then develop cf. ...Read more

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What can I do if my brother has a mild case of cystic fibrosis and my parents are making me get tested?

Cystic fibrosis: Good to know if you have the gene because sometimes clinical symptoms do not develope early. Also knowing if you are a one gene carrier (but not affected) helps with family planning in the future. ...Read more

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If both parents are "carriers" of a cystic fibrosis allele, what are the odds of passing it on?

50%/time: Carrier parents pass either the normal or affected gene at equal(50%) frequency any time they conceive.In a million random parings, 25% would result in cf, 25% in non-carrier & 50% carriers. In practice, the parents could produce all cf, all carrier or all non- carrier kids. ...Read more