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Doctor insights on: Do Antihistamines Mess With You Thyroid

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Dr. Cornelius O'leary jr
13 Doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more


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Do antihistamines mess with you thyroid?

Do antihistamines mess with you thyroid?

Must see an Endo: Need to be seen by an endocrinologist asap. Elevated liver enzymes is not uncommon in individuals with high thyroid levels. Crohns and graves disease are both autoimmune in nature. ...Read more

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I'm due to have a thyroid scan in 3 days. Yesterday, I took two 25 mg antihistamine pills. Will this affect the results?

I'm due to have a thyroid scan in 3 days. Yesterday, I took two 25 mg antihistamine pills. Will this affect the results?

No, it should not.: The half life of most antihistamines should be less than 24 hrs and should be out of the system by then. I would check with the radiology center to confirm their policy. I would also avoid any more antihistamines until the time of testing. ...Read more

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Do antihistamines push you hypo or hyper thyroid?

Do antihistamines push you hypo or hyper thyroid?

Unlikely: There is no data or documentation that states antihistamines can affect the thyroid in an either up or down manner. ...Read more

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Why can not use antihistamines and decongestants in patient with thyroid disease? What is the machanism of action? What medicine can use to relief?

Why can not use antihistamines and decongestants in patient with thyroid disease? What is the machanism of action? What medicine can use to relief?

Decongestants may: Decongestants may complicate and exacerbate hyperthyroid states. In general I do not recommend oral decongestants to any age group as there is a higher risk of cardiovascular disease with decongestant use.
Antihistamines alone may be used in thyroid disease in general. ...Read more

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On antihistamine and sinus medications it says to consult your doctor if you have thyroid disease. Why?

On antihistamine and sinus medications it says to consult your doctor if you have thyroid disease. Why?

Avoid stimulants: Many otc cold medicines have pseudophed or similar stimulant medications. If you are hyperthyroid, this would be an added stimulant. If your heart rate is already 95 from your thyroid, the added stimulant could be bad for your heart. However, if your thyroid is being treated, and your blood ft4 is normal, you are probably ok. ...Read more

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Don't understand how antihistamines work for chronic hives that is due to thyroid issues and not allergies?

Don't understand how antihistamines work for chronic hives that is due to thyroid issues and not allergies?

Chronic Urticaria CU: CU can be associated with various autoimmune disorders. Even in the absence of hypo- or hyperthyroidism, patients with thyroid autoantibodies are often poorly responsive to standard therapies and have more persistent disease. Studies have examined the use of thyroid supplementation in the treatment of CU, with mixed results. Best treatment for this condition is daily antihistamines. See Allergist. ...Read more

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Can chronic autoimmune urticaria go into remission? Will taking levothyroxine for thyroid help stop the hives without taking antihistamines?

Can chronic autoimmune urticaria go into remission? Will taking levothyroxine for thyroid help stop the hives without taking antihistamines?

Yes: The average duration of chronic hives lasts for 5-6 years and thus remission is indeed possible. As for thyroid, I have only had one patient with thyroid antibodies benefited from thyroid replacement out of the many hundreds I have seen over the years. Usually antihistamine would be needed. Studies so far with thyroid replacement have mostly been negative. ...Read more

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Itch all over no rash. Antihistamines and creams no effect. Bloods clear for kid, lib, thyroid. Soap free shower. Scratching. Gbs '09 I had this too?

Itch all over no rash. Antihistamines and creams no effect. Bloods clear for kid, lib, thyroid. Soap free shower. Scratching. Gbs '09 I had this too?

Many possibilities: To help you some additional questions to answer:
1) any travel to outside of us or snorkeling/scuba activity? Some parasites, infections can manifest this way.
2) understand no soap being used - but chemicals are everywhere. Anything new that you are being exposed to?
3) sexually active? Pregnancy, std can cause these symptoms as well
4) psychological factors? Anxiety, depression, ocd, etc. ...Read more

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A small neck rash a few days prior to getting a full body rash very quickly. Appears in a.M. Before foods or meds. Clears fast with no antihistamine?

A small neck rash a few days prior to getting a full body rash very quickly. Appears in a.M. Before foods or meds. Clears fast with no antihistamine?

Urticaria: Urticaria refers to a group of disorders affecting adults and children, in which red patches and weals occur in the skin. A wheel is a swelling of the surface skin.
The skin swelling seen in urticaria is due to the release of chemicals such as histamine from mast cells in the skin which causes small blood vessels to leak. Treatment is with antihistamine or avoidance of the causative agent. ...Read more

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I have an itchy red rash covering most of my torso and neck. My GP gave me antihistamines, how soon should I see a reduction in the rash?

I have an itchy red rash covering most of my torso and neck. My GP gave me antihistamines, how soon should I see a reduction in the rash?

Depends: If it is an allergic reaction, you took the right dose, it would fade in few hours, but might recur, if it something else other than allergy, it needs to be treated accordingly ...Read more

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Noticed rash around my neck last night. Upon waking up, rash is still hot, itchy eyes and a stuffed nose. Should I take an antihistamine, if so what?

Noticed rash around my neck last night. Upon waking up, rash is still hot, itchy eyes and a stuffed nose. Should I take an antihistamine, if so what?

Diphenhydramine: Unless contraindicated, and don't exceed recommended dosage, if it doesn't improve see your doctor ...Read more

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I have welts on my neck after resting my head on a wool pillow. My upper lip is also swollen. I am taking over-the-counter antihistamines.?

Allergy?: Could be an allergy to wool, especially if antihistamines are helping. But hives and swelling could be due to a variety of things including food allergy, medication alley, insect sting, viral infection, or exposure related allergy like the wool. If not improving in a few days see doc ...Read more

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Raised red rash around arm pits (not in pit) and front of neck. Bumps/welts no pus or blisters. Doesn't respond to antihistamines. Began mid April.

Raised red rash around arm pits (not in pit) and front of neck. Bumps/welts no pus or blisters. Doesn't respond to antihistamines. Began mid April.

See your doctor: Or dermatologist, more history and physical examination are needed to reach a diagnosis, hence the right treatment, cannot be done with sketchy picture and limited platform ...Read more

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I have a non itchy rash all over body, on my arms. Legs, stomach, back chest and neck. I have been prescribed a steroid cream and antihistamines. I've been using these for two weeks but the rash has got worse. What could this be?

I have a non itchy rash all over body, on my arms. Legs, stomach, back chest and neck. I have been prescribed a steroid cream and antihistamines. I've been using these for two weeks but the rash has got worse. What could this be?

Needs re-evaluation: Not possible to diagnose without at least a picture, you need to see your doctor again who would refer you to a dermatologist. Please hold the steroid cream for now, it could be a fungal rash or something else, good luck ...Read more

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Woke up with a scratch looking mark which has now spread all over my neck chest and shoulders as a rash. Benadryl isn't working. No insurance?

Woke up with a scratch looking mark which has now spread all over my neck chest and shoulders as a rash. Benadryl isn't working. No insurance?

Hard to tell: It is not possible to tell you what may be the cause without more history and a direct inspection of the rash. I suspect that they may be from a mild case of hives. Best to see a doctor but you may try taking a non-sedating antihistamine up to 4 x daily to see if this would work for you in the meanwhile. ...Read more

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14 y old son has a sunburn and 50+ tiny bug bites on his neck from micro caterpillars at the Lacrosse field. Benadryl (diphenhydramine) every 4 hrs. Not helping much?

14 y old son has a sunburn and 50+ tiny bug bites on his neck from micro caterpillars at the Lacrosse field. Benadryl (diphenhydramine) every 4 hrs. Not helping much?

Sunburn/bites: He may require a short course of PO steroid treatment in addition to antihistamines. Keep the area clean and try cold packs and neosporin. All the best. ...Read more

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I have a outbreak on my back, arms, Neck in shoulders it itchy and looks like scratches I've been taking Benadryl (diphenhydramine) for the past two day. Not working?

I have a outbreak on my back, arms, Neck in shoulders it itchy and looks like scratches I've been taking Benadryl (diphenhydramine) for the past two day. Not working?

See doc: It is difficult to know what you have without more details. If you have a contact allergy, Benadryl (diphenhydramine) would not work for you but a hydrocortisone cream may. If the problem is that bothersome, you should see your doctor. ...Read more

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Breaking out in little hives on face, neck, &chest for weekn a half. What could it be? Itchy! I break out, take Benadryl (diphenhydramine) n they go down, itch, then back.

Breaking out in little hives on face, neck, &chest for weekn a half. What could it be? Itchy! I break out, take Benadryl (diphenhydramine) n they go down, itch, then back.

See a dermatologist: It is difficult to make a proper diagnosis since I am not there to see the condition. I recommend seeing a dermatologist so that they can make a proper diagnosis and give you something to get rid of the condition or relieve symptoms. ...Read more

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I have hot and itchy ears also neck and body and when I brush my hair I get a sensation I am taking antistamines which do stop it?

I have hot and itchy ears also neck and body and when I brush my hair I get a sensation I am taking antistamines which do stop it?

External Otitis: This is external otitis. You need to get an Rx for antibiotic/cortisone ear drops such as Cortisporin, (neomycin polymyxin and hydrocortisone)
Don't put heat to the ear. Keep soap out of the ear. ...Read more

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Forearms, neck and face get red and warm to the touch, every day. Take Benadryl (diphenhydramine) to keep calm, but it came from nowhere, week 5, no known allergy, why?

Forearms, neck and face get red and warm to the touch, every day. Take Benadryl (diphenhydramine) to keep calm, but it came from nowhere, week 5, no known allergy, why?

Not allergy: These are not typical allergy symptoms. You need to consult an allergist to find out if you have a mast cell disorder since Benadryl (diphenhydramine) seems to help. ...Read more

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My Baby is 2 and a half and has really bad eczema on her arms, neck, and now her face. Can I apply benadryl (diphenhydramine) cream to help with the itching?

My Baby is 2 and a half and has really bad eczema on her arms, neck, and now her face. Can I apply benadryl (diphenhydramine) cream to help with the itching?

No do not use: Benadryl (diphenhydramine) cream. Get some aveeno oatmeal bath packets and put her in the bathtub with one of these packets dissolved to soothe the itch. They should help a lot. You can also use 1% hydrocortisone cream twice a day on lesions. These may help a bit. See her Dr. For something stronger. ...Read more

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My wife took Benadryl (diphenhydramine) yesterday for a cold and woke with her eye swollen and a rash on her neck. Could she be allergic to benadryl (diphenhydramine)?

My wife took Benadryl (diphenhydramine) yesterday for a cold and woke with her eye swollen and a rash on her neck. Could she be allergic to benadryl (diphenhydramine)?

Unlikely: Although allergic reactions to Benadryl (diphenhydramine) or the dye in the Benadryl (diphenhydramine) have rarely been implicated in allergic reactions, the more likely explanation is that the infection itself is contributing to hives and swelling. This can especially be seen with viruses and less likely with bacteria and usually more common in children. ...Read more

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Red bums like rash from neck to butt very itchy has had em about 4 days tried benadryl (diphenhydramine) cortisone cream calamine lotion nothing seems to help?

Red bums like rash from neck to butt very itchy has had em about 4 days tried benadryl (diphenhydramine) cortisone cream calamine lotion nothing seems to help?

Eval: Can’t diagnose with available information. Examination, history & possibly other testing would be needed to make an accurate diagnosis. Treatment would be dictated by diagnosis. ...Read more

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She has a flat bumpy rash on one cheek that is spreading to the neck and forehead, no fever, cough, or any other symptoms. Benadryl (diphenhydramine) was no help.

She has a flat bumpy rash on one cheek that is spreading to the neck and forehead, no fever, cough, or any other symptoms. Benadryl (diphenhydramine) was no help.

See a doctor: Without seeing this and getting a full history it is impossible to speculate as to cause, but this should be shown to a medical professional for evaluation. ...Read more

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Small cluster of hives on legs every night but back and back of neck occasionally for months now. Absolutely no signs of bedbugs. Been taking benadryl (diphenhydramine)?

Small cluster of hives on legs every night but back and back of neck occasionally for months now. Absolutely no signs of bedbugs. Been taking benadryl (diphenhydramine)?

Chronic Urticaria: Chronic idiopathic or spontaneous urticaria (hives) is the persistence of hives on most days of the week for a period of 6 weeks or longer. It is not due to any medication or food trigger. No specific cause can be identified in most patients with this condition. Treatment involves daily doses of non-sedating antihistamines like Zyrtec (cetirizine). See Allergist for more details and treatment options ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Paul Carter
648 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more