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Doctor insights on: Do Antidepressants Cause Restless Legs Syndrome

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Do antidepressants cause restless legs syndrome?

Do antidepressants cause restless legs syndrome?

Meds can trigger RLS: What "causes" RLS is uncertain. It may be related to genetics, deficiency of iron in the brain, hormonal changes, pregnancy, parkinson's disease. Medications like antidepressants, antipsychotics, cold and allergy medications can trigger or aggravate rls. Treatment with medication can help diminish symptoms. ...Read more

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Akathisia (Definition)

The best way to consider akathisia is to imagine the need to move. Patients with this condition have major problems sitting still. They have a need to move. This can be a side effect of medication, may be associated with disease such as parkinsons, or may be a normal variant. Most doctors use it it describe the ...Read more


Emily Lu Dr. Lu
5 doctors agreed:
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Do antidepressants cause restless leg syndrome?

Emily Lu Dr. Lu
5 doctors agreed:
Do antidepressants cause restless leg syndrome?

Sometimes: Akisthesia (an inner restlessness that can manifest very much like restless legs syndrome) has been reported as a side effect of some antidepressants like prozac, Paxil (paroxetine) and tricyclic antidepressants. However, it is more commonly seen in patients that are on antipsychotic drugs like haldol. ...Read more

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Is there a connection between antidepressants and symptoms of restless leg syndrome?

Could be, but: Details of rls, see my prior answer. Antidepressants may be associated with rls, but poor sleep state, fatigue, other sx of depression may also lead to rls. In these cases antidepressants may, in fact, help.It must be used correctly dx, and monitored carefully; as with any psychotropic drug, each interacts differently from 1to other. C primary care doc for DX or rx or proper referral. ...Read more

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If someone has depression & restless leg syndrome due to renal failure, what type of antidepressant is best. Dopamine agonist, ssri, benzo, or combo.

If someone has depression & restless leg syndrome due to renal failure, what type of antidepressant is best. Dopamine agonist, ssri, benzo, or combo.

Many choices: You need to talk to your physician because there are many other issues we cannot cover. Since you have both depression renal failure and restless legs each needs specific diagnostic evaluation help answer your question. ...Read more

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Any connection between anti depressants and symptoms of restless leg syndrome?

Any connection between anti depressants and symptoms of restless leg syndrome?

Yes: Some prescription medicines can worsen rls, including anti-depressants, anti-histamines, and anti-nausea medications. Consider consultation with a sleep medicine specialist for further information. ...Read more

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Can flexeril (cyclobenzaprine hcl) cause restless legs syndrome to worsen? Is it possible to also feel it in your arms?

Can flexeril (cyclobenzaprine hcl) cause restless legs syndrome to worsen? Is it possible to also feel it in your arms?

It cannot: The RLS and restless arms/hands syndrome are neurological, sleep movement disorders and treated with Dopamine agonists such as ropinirole (approved in rls) or pramipexole. Many practitioner use Flexeril (cyclobenzaprine hcl) as a muscle relaxant and sleep inducer as an adjunctive medication. Rec.: see sleep specialist for more information. ...Read more

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What are possible causes of restless leg syndrome?

What are possible causes of restless leg syndrome?

Often not clear: Some patients have low iron levels and those that do can have symptom relief when iron is supplemented. There is a genetic component to restless legs syndrome as it often runs in families. Many patients don't have an underlying cause. ...Read more

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Has the cause for restless leg syndrome been figured out yet?

Has the cause for restless leg syndrome been figured out yet?

RLS: Cause unknown in most cases, but it is noted to occur more in chronic kidney diseases, diabetes, iron deficiency, parkinson's disease, peripheral neuropathy, pregnancy, sedatives withdrawal & some medications such as caffeine/lithium/neuroleptics. ...Read more

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Dr. Michelle Zetoony
366 doctors shared insights

Restless Leg Syndrome (Definition)

Urge to move: irresistible, involves legs but may involve arms and trunk worse at rest relieved with movement (no symptoms during movement) but may recur once a person stops moving/walking worse in the ...Read more


Dr. Alan Wartenberg
231 doctors shared insights

Restless Legs Syndrome (Definition)

Restless leg syndrome is a disorder in which there is an urge or need to move the legs ...Read more