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Doctor insights on: Dna Link Colon Cancer Chromosome

Sometimes: Some colon cancers are related to specific genetic mutations but the majority are not. ...Read more

Sometimes: Some colon cancers are related to inheritable genetic mutations but the majority are not. ...Read more

A minority is.: Pancreatic adenocarcinoma, arising from ducts/epithelial tissue, is mainly "sporadic", but can run in families. Pancreatic cancer has also been related to brca mutation, fammm syndrome, and some other inherited conditions. The familial pancreatic cancer registry is at johns hopkins. A minority of neuroendocrine tumors of the pancreas are associated with multiple endocrine neoplasia (men) syndromes. ...Read more

Possible: In a sense all cancer is "genetic" in that it occurs do to changes in dna that cause cancer formation. However, if your questions is about familial/inherited cancer, then most uterine cancer is not from an inherited increased cancer risk. But some uterine cancer may be related to cancer risk genes such as brca 1/2 and other genes. Genetic counselors can help determine. ...Read more

Sometimes: Certain genotypes such as the brca mutations have a higher incidence of ovarian cancer. ...Read more

Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more

Genes: Most colon cancers are not inherited. However, there is a subset which is associated with inherited genetic abnormalities such as hereditary polyposis a this hereditary non polyposis gene (hnpp). There are also syndromes that make you susceptible to a variety of different cancers including colon cancer such as lynch syndrome. ...Read more

Yes : Colon cancer can be genetic and there a re criteria that can apply and genetic testing is available. There is also a blood level you can check called cea . For stomach cancer like adenocarcina there is no genetic testing. There are familial syndromes like men that can cause stomach tumors called gastronomas or ze syndrome. If concerned can talk to your doctor. But overall these things very rare. ...Read more

No: We are not that sophisticated yet!

Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read more

Mostly due to HPV: Most vaginal cancers are not related to any inherited genetic risk but instead are due to the sexually transmitted human papilloma virus (hpv). The same high-risk types that cause cervical cancer and precancerous changes can have the same effect on the vagina, vulva, and anus. ...Read more

Somehow yes: There is some genetic predisposition in families with hx. Of colorectal cancer. Diet also plays a rol ( low fiber diet increases cancer). Familiar poliposis increases chances of colon cancer. Colon polyps may degenerate in cancer. Small intestine cancers are rare and difficult to find. In general there are families affected by cancers and families affected by atherosclerosis but both together too. ...Read more

Some forms are: There are a number of hereditary forms of kidney cancer (renal cell carcinoma), most frequently von hippel lindau. Others include tuberous sclerosis complex, hereditary non-vhl clear cell renal cell carcinoma, hereditary papillary renal cell carcinoma (hprcc), birt-hogg-dubé syndrome (bhd), and hereditary leiomyomatosis/renal cell carcinoma (hlrcc). These have specific findings for each. Ask a doc. ...Read more

Only some: Many cancers occur sporadically. Breast cancer, ovarian cancer , familial colon adenomatosis polyposis , hereditary nonpolyposis colorectal cancer , multiple endocrine neoplasia ii, multiple endocrine neoplasia i, von hippel-lindau, ; li-fraumeni syndrome can be genetically linked. ...Read more

Chemoresistance: In metstatic colorectal cancer combinations of chemotherapy utilized. Drug combos such as FOLFOX are employed. With a poor response, immunotherapy is added such as the VEGF receptor antibodies or those targeting epidermal growth factor receptors like Erbitux and Vectibix (panitumumab). If the standard or wild type Kras is present in mets, there is a fairly good response but neg activity in mutated Kras. ...Read more

We're Getting There: In the past, we used anatomic staging alone (tumor size, lymph node involvement) to guide rx. Gene profiling allows us a completely separate measure of prognosis, and, more importantly, can predict who may or may not benefit from different chemotherapy agents. In the future, we will hopefully be able to tailor our rx to the specific cancer being treated: the elusive personalized medicine. ...Read more

Yes: The large intestine and the colon are words to describe the same anatomic structure in the abdomen. ...Read more

None of these: Are linked genetically, to environmental exposures, or familial clusters. ...Read more

Unknown: Cardiac tumors are so rare, there are no treatment guidelines or clinical trials to answer any questions about them. Most tumors in the heart come from other places and don't originate from the heart itself. The one true "heart cancer" is a cardiac sarcoma. As far as we know, it is not genetic. ...Read more

Many: If you inherit mutated brca1 or brca2 from a parent, your odds are greatly increased. All cancers arise from accumulated mutations and natural selection over your own lifetime, but these can actually be passed from parent to child. ...Read more