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Doctor insights on: Dna Link Colon Cancer Chromosome

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Is colon cancer genetic?

Is colon cancer genetic?

Sometimes: Some colon cancers are related to specific genetic mutations but the majority are not. ...Read more

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Dr. Barry Rosen
4,368 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is bowel cancer genetic?

Is bowel cancer genetic?

Sometimes: Some colon cancers are related to inheritable genetic mutations but the majority are not. ...Read more

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Is pancreatic cancer genetic?

Is pancreatic cancer genetic?

A minority is.: Pancreatic adenocarcinoma, arising from ducts/epithelial tissue, is mainly "sporadic", but can run in families. Pancreatic cancer has also been related to brca mutation, fammm syndrome, and some other inherited conditions. The familial pancreatic cancer registry is at johns hopkins. A minority of neuroendocrine tumors of the pancreas are associated with multiple endocrine neoplasia (men) syndromes. ...Read more

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Is uterine cancer genetic?

Is uterine cancer genetic?

Possible: In a sense all cancer is "genetic" in that it occurs do to changes in dna that cause cancer formation. However, if your questions is about familial/inherited cancer, then most uterine cancer is not from an inherited increased cancer risk. But some uterine cancer may be related to cancer risk genes such as brca 1/2 and other genes. Genetic counselors can help determine. ...Read more

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Is ovarian cancer genetic?

Is ovarian cancer genetic?

Sometimes: Certain genotypes such as the brca mutations have a higher incidence of ovarian cancer. ...Read more

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Why is the colon prone to cancer in hnpcc (hereditary nonpolyposis colorectal cancer)?

Genetic mutations: HNPCC or hereditary nonpolyposis colorectal cancer is an autosomal dominant genetic condition that has a high risk of colon cancer The disease first described by Lynch and is associated with other cancers including endometrial ovary and stomach. The increased risk is due to inherited mutations that impair DNA mismatch repair. .Individuals with HNPCC have an 80% lifetime risk for colon ca. ...Read more

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How is colon cancer inherited?

How is colon cancer inherited?

Genes: Most colon cancers are not inherited. However, there is a subset which is associated with inherited genetic abnormalities such as hereditary polyposis a this hereditary non polyposis gene (hnpp). There are also syndromes that make you susceptible to a variety of different cancers including colon cancer such as lynch syndrome. ...Read more

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Are there any stomach cancer and colon cancer molecular screening tests?

Are there any stomach cancer and colon cancer molecular screening tests?

Yes : Colon cancer can be genetic and there a re criteria that can apply and genetic testing is available. There is also a blood level you can check called cea . For stomach cancer like adenocarcina there is no genetic testing. There are familial syndromes like men that can cause stomach tumors called gastronomas or ze syndrome. If concerned can talk to your doctor. But overall these things very rare. ...Read more

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Are breast cancer and colon cancer linked?

Are breast cancer and colon cancer linked?

Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read more

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Is vaginal cancer genetic?

Is vaginal cancer genetic?

Mostly due to HPV: Most vaginal cancers are not related to any inherited genetic risk but instead are due to the sexually transmitted human papilloma virus (hpv). The same high-risk types that cause cervical cancer and precancerous changes can have the same effect on the vagina, vulva, and anus. ...Read more

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Is bowel cancer hereditary?

Is bowel cancer hereditary?

Somehow yes: There is some genetic predisposition in families with hx. Of colorectal cancer. Diet also plays a rol ( low fiber diet increases cancer). Familiar poliposis increases chances of colon cancer. Colon polyps may degenerate in cancer. Small intestine cancers are rare and difficult to find. In general there are families affected by cancers and families affected by atherosclerosis but both together too. ...Read more

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Is kidney cancer genetic?

Is kidney cancer genetic?

Some forms are: There are a number of hereditary forms of kidney cancer (renal cell carcinoma), most frequently von hippel lindau. Others include tuberous sclerosis complex, hereditary non-vhl clear cell renal cell carcinoma, hereditary papillary renal cell carcinoma (hprcc), birt-hogg-dubé syndrome (bhd), and hereditary leiomyomatosis/renal cell carcinoma (hlrcc). These have specific findings for each. Ask a doc. ...Read more

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Is cancer genetic?

Is cancer genetic?

Only some: Many cancers occur sporadically. Breast cancer, ovarian cancer , familial colon adenomatosis polyposis , hereditary nonpolyposis colorectal cancer , multiple endocrine neoplasia ii, multiple endocrine neoplasia i, von hippel-lindau, ; li-fraumeni syndrome can be genetically linked. ...Read more

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Is there a difference between kras wild and KRAS mutant colon cancer?

Chemoresistance: In metstatic colorectal cancer combinations of chemotherapy utilized. Drug combos such as FOLFOX are employed. With a poor response, immunotherapy is added such as the VEGF receptor antibodies or those targeting epidermal growth factor receptors like Erbitux and Vectibix (panitumumab). If the standard or wild type Kras is present in mets, there is a fairly good response but neg activity in mutated Kras. ...Read more

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Gene expression profiling predicts clinical outcome of breast cancer?

Gene expression profiling predicts clinical outcome of breast cancer?

We're Getting There: In the past, we used anatomic staging alone (tumor size, lymph node involvement) to guide rx. Gene profiling allows us a completely separate measure of prognosis, and, more importantly, can predict who may or may not benefit from different chemotherapy agents. In the future, we will hopefully be able to tailor our rx to the specific cancer being treated: the elusive personalized medicine. ...Read more

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Large intestinal cancer. Is that colon cancer?

Large intestinal cancer. Is that colon cancer?

Yes: The large intestine and the colon are words to describe the same anatomic structure in the abdomen. ...Read more

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Is heart cancer genetic?

Is heart cancer genetic?

Unknown: Cardiac tumors are so rare, there are no treatment guidelines or clinical trials to answer any questions about them. Most tumors in the heart come from other places and don't originate from the heart itself. The one true "heart cancer" is a cardiac sarcoma. As far as we know, it is not genetic. ...Read more

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What type of genetic mutation causes breast cancer?

What type of genetic mutation causes breast cancer?

Many: If you inherit mutated brca1 or brca2 from a parent, your odds are greatly increased. All cancers arise from accumulated mutations and natural selection over your own lifetime, but these can actually be passed from parent to child. ...Read more

Dr. Dariush Saghafi
13 doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dna (Definition)

Dna are the coding molecules found in all living things on earth which contain the instructions on how to build living things. Its is comprised the nucleotide molecules which are ...Read more