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Doctor insights on: Dna Fragmentation

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Is DNA fragmentation related to morphology?

Is DNA fragmentation related to morphology?

Semen?: yes, and shows a general problem in male fertility. Occurs with age, low sperm counts and any condition taht does that. ...Read more

Dna (Definition)

Dna are the coding molecules found in all living things on earth which contain the instructions on how to build living things. Its is comprised the nucleotide molecules which are ...Read more


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Can DNA fragmentation determine failure in embryo implantation ?

Can DNA fragmentation determine failure in embryo implantation ?

No: Dna fragmentation testing is typically done on sperm, not embryos. Studies have not confirmed that high dna fragmentation of sperm correlate with embryo implantation, so I do not recommend this test. Embryo implantation failure is more likely to be related to aneuploidy. ...Read more

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What is DNA fragmentation ? Is it a temporary condition , what causes this , can it be treated and what impact can it have on an IVF attempt ?

What is DNA fragmentation ? Is it a temporary condition , what causes this , can it be treated and  what impact can it have on an IVF attempt ?

DNA breakage: At the end of the day, it's really the structure and functioning of sperm dna that has to be "normal" for an egg to fertilize in ivf. If the sperm dna is heavily fragmented, pregnancy may not occur, or if it does it can miscarry. Frag occurs for many reasons like smoking or chemical exposure or varicocele. I try to either fix these or certainly consider icsi. ...Read more

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We have 60% DNA fragmentation, I've had 1 failed IVF with cgh normals blasts , I have frozen blast , should I transfer those or do a fresh IVF ?

We have 60% DNA fragmentation,  I've had 1 failed IVF with cgh normals blasts  , I have frozen blast  , should I transfer those or do a fresh IVF ?

IVF with aCGH: Unfortunately, even after PGS and transfer of normal embryos, the cycle may not work. However, a lot has to do with the quality of the embryos transferred. I'd review the results with your doctor if you have more euploid (normal) embryos remaining and consider a Frozen transfer if possible. ...Read more

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How to improve sperm quality and DNA fragmentation for icsi?

How to improve sperm quality and DNA fragmentation for icsi?

Not too many options: Unfortunately there aren't many options for improving sperm quality. If there is a varicocele it can be treated. Antioxidants may also help with improving sperm quality. Good luck. ...Read more

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What is DNA printing for?

What is DNA printing for?

Establish paternity: dna fingerprinting is a method of making images of dna sequences in order to study them . It has been used to solve criminal cases and in paternity disputes ...Read more