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Doctor insights on: Dna Antibody

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What are anti-dna antibodies?

What are anti-dna antibodies?

Autoimmune diseases: Anti-dna antibodies, a blood test done when suspecting connective tissue diseases also known as autoimmune diseases (example: lupus). The body immune system makes antibodies to attack its own dna resulting in illness. Caution: blood test alone will not make the diagnosis. Typical symptoms plus test are needed for diagnosis. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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How to measure anti-dna antibody using farr assay?

How to measure anti-dna antibody using farr assay?

Radioactivity: The farr assay is a radioimmunologic assay. It uses radiolabeled antigens to detect specific antibodies in serum. The antigens are allowed to react with the serum and then precipitated using a special reagent such as protein a sepharose beads. The bound radiolabeled immunoprecipitiate is commonly analzyed by gel electrophoresis. ...Read more

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How does anti DNA antibody come from lupus?

How does anti DNA antibody come from lupus?

Anti-DNA antibody: People with lupus develop abnormal substances in their blood called antibodies. These antibodies attack various organs of the body and cause the signs and symptoms of the disease. Anti-dna antibody is one such substance. The exact reason why people develop these antibodies is not known but there is often a genetic component (family history). ...Read more

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How do you measure anti-dna antibody? Using elisa?

How do you measure anti-dna antibody? Using elisa?

Anti-DNA antibodies: Simple blood tests can be performed to test for anti-dna antibodies. Usually the screen is started with a basic ANA test which can then be followed with more specific antibody testing to determine if a specific disease can be identified. Of course, symptoms must also correlate since we do not simply provide diagnosis based on lab findings. ...Read more

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What are anti-dna antibodies?

Autoimmune diseases: Anti-dna antibodies, a blood test done when suspecting connective tissue diseases also known as autoimmune diseases (example: lupus). The body immune system makes antibodies to attack its own dna resulting in illness. Caution: blood test alone will not make the diagnosis. Typical symptoms plus test are needed for diagnosis. ...Read more

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What is the anti-dna antibodies?

What is the anti-dna antibodies?

Suggestive of SLE!: Buyt I said suggestive. The titer of double stranded dna antibodies is more important than the presence of the antibody. Other tests are necessary to confirm the DX and activity of disease, if present. ...Read more

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What is the measurement of anti-dna antibodies about?

What is the measurement of anti-dna antibodies about?

Autoimmunity: Sometimes, the immune system makes antibodies that attack your own tissues. This occurs in disorders such as lupus, rheumatoid arthritis, and others. Anti-dna antibodies are just one form of antibody that are seen in autoimmune disorders. A high level of anti-dna antibodies should be evaluated by an immunologist or rheumatologist. ...Read more

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What is the definition or description of: anti DNA antibodies?

What is the definition or description of: anti DNA antibodies?

Anti nuclear Ab: Briefly, anti dna antibodies are antinuclear antibodies that are used in the diagnosis of the autoimmune disease systemic lupus erythematosis, sle.

There are antibodies against double stranded dna and single stranded dna. The former is useful in the case of sle. It is probably released from dying cells in a process that appears to be defective in this disease. This is fairly specific to sle. ...Read more

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What to do if I had a level or value of 266 for a DNA antibodies, native lab test. Does anyone know what that means?

What to do if I had a level or value of 266 for a DNA antibodies, native lab test. Does anyone know what that means?

Insufficient info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you have not provided enough information for a meaningful opinion. DNA antibody tests are usually done in autoimmune diseases like Lupus. ...Read more

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My rheumatologist confirmed that I have anti DNA antibodies. What tests next?

AntiDNA: Sometimes anti-smith antibodies are tested or other testing for lupus or a related disorder. It depends on your signs and symptoms. Biopsies are sometimes required. The connective disease family is extensive and overlaps occur. That is why I trust rheumatologists. ...Read more

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My rheumatologist confirmed that I am + anti DNA antibodies but he will not confirm it as lupus, what else could it be?

My rheumatologist confirmed that I am + anti DNA antibodies but he will not confirm it as lupus, what else could it be?

Many things: 1. Positive antibodies can proceed the onset of disease. 2. It could be a false positive. 3. Low titers, especially if IgA can be seen in healthy populations. Accuracy also depends on the type of test that was used whether it was ELISA or ria. No test in medicine is 100% and rheumatology tests are worse than most. ...Read more

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Had bloods for lyme, anca, anti DNA antibodies, anti mitochondrial all negative. If autoimmune started 7 years ago tho wouldn't blood repair to normal?

Had bloods for lyme, anca, anti DNA antibodies, anti mitochondrial all negative. If autoimmune started 7 years ago tho wouldn't blood repair to normal?

No: Autoantibodies rarely become negative if they were positive. It may rarely happen if the disease is in complete remission. However, that almost never happens. ...Read more

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There are DNA, Proteins, Antibody/Antigens. But what's used while detecting the presents of Toxins (ID's, drugs, chemicals, ect)?

There are DNA, Proteins, Antibody/Antigens. But what's used while detecting the presents of Toxins (ID's, drugs, chemicals, ect)?

Toxins: I am not sure I understand your question. If you have a certain toxin in mind that you would like to know how to detect, I recommend that you name that. There is direct and indirect toxin measurement, again depending on the toxin. ...Read more

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If you made a customized microarray with no limitations-How would you rule out all known Pathogens. DNA, Proteins, Antibodies/Antigens. What else?

If you made a customized microarray with no limitations-How would you rule out all known Pathogens. DNA, Proteins, Antibodies/Antigens. What else?

See John Rumsfeld: Who coined the term " unknown knowns". We will never unravel all of the pathogens even if we have knowledge of all current DNAs since they alone do not define pathogenicity and may change with time and modified by environmental interactions. ...Read more

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Chemicals, Toxins, illegal/legal drugs. Do they teach that all of these have a DNA sequence? . ..learning about DNA, Protein, Antibodies/Antigens, ect

No: The chemicals you mentioned are not DNA. Some toxins are proteins, others are different chemicals. The gene controlling the proteins have a DNA sequence but the proteins and chemicals do not. ...Read more

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The only pos blood test I have is ANA of 1:320. Neg RF CCP DNA and SM antibody was low of 10. Extreme joint pain 6 mnth. RA, lupus, or neither?!

The only pos blood test I have is ANA of 1:320. Neg RF CCP DNA and SM antibody was low of 10. Extreme joint pain 6 mnth. RA, lupus, or neither?!

+ ANA: There are other spondyloarthropathy that can cause a lot of pain and will require treatment. Did they do an HBLA27 test? Make sure you f/u with your rheumatologist. If you have RA you can get these results. You may need to start a biologic medication. Good luck and feel better soon) ...Read more

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Does the DNA/RNA store antigen/antibody information? Or is this only on the outside of the cell (exterior)?

Does the DNA/RNA store antigen/antibody information? Or is this only on the outside of the cell (exterior)?

Great Question!: This is a big topic in the immunology field! Antigens tend to be stored in the DNA, but Antibodies are the product of many interactions between DNA, RNA and Proteins that we don't fully undestand. If you are realy intrested in this topic, start your studies in Molecular Biology and go from there!! ...Read more

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I'm having negative DNA, Sm and Rnp antibodies, but positive sm/rnp antibody, and high ANA titre speckled, so what is the diagnosis?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

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How many different ways can a pathogen be detected? Is 1 way better then another for all pathogens? Example: antibody-antigen-dna/rna-proteins.?

How many different ways can a pathogen be detected? Is 1 way better then another for all pathogens? Example: antibody-antigen-dna/rna-proteins.?

Many: A pathogen is any micro-organisms that causes disease. We find different pathogens by different techniques -- prions (which count as pathogens) only by chemistry, many by polymerase chain reaction, seeking antibodies, growing them (most bacteria, some viruses), or seeing them under the microscope. There's no one-size-fits-all. ...Read more

Dna (Definition)

Dna are the coding molecules found in all living things on earth which contain the instructions on how to build living things. Its is comprised the nucleotide molecules which are ...Read more


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