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Doctor insights on: Divalproex Sodium Delayed Release Tablets Dosage

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So does that mean i can take the pill plan b even if im taking medication for seizures it's called divalproex delayed?

So does that mean i can take the pill plan b even if im taking medication for seizures it's called divalproex delayed?

Not big problem: Would suggest contacting the doctor who treats your seizures, and discuss if any need to adjust your dose, but otherwise, would not be too concerned about drug drug interactions under these circumstances. ...Read more

Dr. Jeffrey Cohen
237 doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, ..Etc.It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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I'm on clomipramine 75mg od. Now suffering severe convulsions and recurrent thoughts since last one week.Divalproex sodium will be good choice for me?

I'm on clomipramine 75mg od. Now suffering severe convulsions and recurrent thoughts since last one week.Divalproex sodium will be good choice for me?

Call physican: Clomipramine may indeed induce seizures, but usually at a much higher dose. When considering your other medications, however, you are on three potent serotonin modulators, and the interactions amongst the three may be a problem. You may also be at a higher risk for seizures if you have had ECT recently. Please call and consult with your psychiatrist about this in detail. ...Read more

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Divalproex sodium DR 250mg. I know I'm not bipolar but yeah was put on this any ways. Can it kill me that I'm taking it and not bipolar?

Divalproex sodium DR 250mg. I know I'm not bipolar but yeah was put on this any ways. Can it kill me that I'm taking it and not bipolar?

Insufficient data: Please repost and include why you ARE taking it, not what you DON'T have; such info is useless. Also who prescribed it, why you are on such a low dose, & why the prescriber saw fit to prescribe a known teratogen to a woman of childbearing age. Some have recommended that NO women of childbearing age be on Depakote for this reason. ...Read more

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Taking Divalproex sodium DR 250mg. I'm only taking it once a day only at night. Is that okay? Is that bad only taking it once a day instead of two?

Taking Divalproex sodium DR 250mg. I'm only taking it once a day only at night. Is that okay? Is that bad only taking it once a day instead of two?

Comments: You provide no clue as to why you are taking Divalproex sodium, but once daily in the non-ER form could well be insufficient to control your problem beyond half a day. Suggest Concierge visit to get this ironed out. ...Read more

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If benzos are addictive, why isn't divalproex sodium; both affect GABA?

If benzos are addictive, why isn't divalproex sodium; both affect GABA?

They act differently: and the primary effect of valproate is NOT on GABA receptors but on sodium channels, and it's GABA effects are different from benzos in terms of GABA subreceptors. NO drug is addictive. People have underlying predispositions, inherited or acquired, and drugs that can produce physical dependency can trigger addiction in those patients. Depakote and other seizure meds have little/no abuse potential ...Read more

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I hav problem of epilepsy since last 10 years, I m using divalproex sodium 500 mg 2 times . First 8 years I had used with 250 in 2 times but I still?

I hav problem of epilepsy since last 10 years, I m using  divalproex sodium 500 mg 2 times . First 8 years I had used with 250 in 2 times but I still?

Therapeutic levels: Divalproex dose is correlated with effect, i, e., sz control, and appropriate blood levels. You may have weighed less 10-12 years ago, and now require a higher dose to control your szs. Not clear whether this dose works well, controls your problem, or causes side effects. Best to get updated with your neurologist. ...Read more

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On average, do people tend to gain more weight on gabapentin or divalproex sodium?

On average, do people tend to gain more weight on gabapentin or divalproex sodium?

No but see your PCP.: Both medications have been known to cause weight gain , one not more than the other. However, there are other factors that can also make you gain weight, the use of other medications, poor eating habits, lack of exercis. ...Read more

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What are the effects of divalproex sodium?

Many: Commonest: weight gain, hair loss, fatigue, loss of balance, fatigue, mental slowing, interaction with multiple drugs. Depending on the indication for which this drug is prescribed, there be several good alternatives with lesser side-effects. Remember, no drug is side-effect free. ...Read more

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I know that divalproex sodium can increase shbg, thereby reducing free testosterone, but does it have any effect on total t in men?

I know that divalproex sodium can increase shbg, thereby reducing free testosterone, but does it have any effect on total t in men?

See answer: You are correct. Most of the anti-epileptic drugs (aeds) increase shbg and reduce free t. Even though aeds may raise total t levels because of this effect on shbg, the total t levels almost always remain within the wide normal range for total t (~300-1100 ng/dl) depending on the reference range used by a given lab. Free t and albumin-bound t (bioavailable t) are the active forms of t in the body. ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more


Dr. Rex Mahnensmith
2,023 doctors shared insights

Sodium (Definition)

It's an element that is important in the cell functions ...Read more