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Doctor insights on: Diseases That Cause Low Creatinine Levels

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What can cause a low creatinine level?

What can cause a low creatinine level?

Low muscle mass: Serum creatinine is a waste product of muscle metabolism. Large muscle mass people have larger creatinine, small muscle mass (women, the elderly) folks have lower creatinine. ...Read more

Dr. Madhu Kandarpa
2,169 doctors shared insights

Creatinine (Definition)

It is a byproduct of creatine phosphate which is present in muscles. Levels are increased ...Read more


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My blood work shows creatinine level quite low-.39. Since Sept, extremely weak in my muscles/fatigue easily/must rest often. What would cause this?

My blood work shows creatinine level quite low-.39.  Since Sept, extremely weak in my muscles/fatigue easily/must rest often.  What would cause this?

Many things: The low creatinine suggests that you have low muscle mass. It isn't clear if this is based on your being small or due to a concerning problem. Many things can cause this like a primary muscle problem, metabolic issues, hormonal issues, nutritional deficiency and low grade infections. You will be best served by reviewing your issues with a physician to better create a course of action. ...Read more

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What's the indicator that a person has kidney disease? Is it low calcium, abnormal Intact PTH, high Creatinine level, or what? Explain.

What's the indicator that a person has kidney disease? Is it low calcium, abnormal Intact PTH, high Creatinine level, or what? Explain.

Several things: Hi. Depending on the type of kidney disease, Several things are possible, but the most general lab test is an increase in serum creatinine. Some kidney diseases can present with normal creatinine and an increase in urinary protein, increase in blood pressure, blood in the urine, etc. Please see a kidney doctor (nephrologist) to be evaluated. They are excellent physiologists and physicians. ...Read more

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What causes EPO level to drop. Can it be something not serious. Kidneys scan and ceatinine level in blood normal. Got moderate anemia. Epo low. 70 yrs?

What causes EPO level to drop. Can it be something not serious. Kidneys scan and ceatinine level in blood normal. Got moderate anemia. Epo low. 70 yrs?

Anemia in a 70'er: The 70 year old person likely has chronic kidney disease (CKD), despite having a normal level creatinine. Have that person see a nephrologist for a 24 hour urine for creatinine clearance to assess the person's kidney function. It the glomerular filtration rate (GFR) is ...Read more

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Is 1.21 creatinine level low?

No: It is in the normal range and there is no pathologic low level of creatinine. See this site for more info. http://www.mayoclinic.com/health/creatinine/my00144/dsection=results. ...Read more