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Doctor insights on: Diseases Of Tissues

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How does one identify Peyronie's disease scar tissue? Feel, look like?

How does one identify Peyronie's disease scar tissue? Feel, look like?

Site of curvature: Peyronie's disease occurs when the normally elastic tissue within the penis is replaced with non-elastic "scar" tissue ("plaque"). This can often be felt at the site where the penis is curving: it will be harder than the surrounding tissue. ...Read more

Tissue (Definition)

The body is composed of tissue that are classically described as beiing derived from three basic embyonic layers known as the endoderm, mesoderm and ectoderm that then differentiate into the structures that compose the body such as skin, soft tissues, bone, muscle, organs, etc. Stem cells are not differentiated and have the potential to ...Read more


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How would one identify Peyronie's disease scar tissue? How would it feel and look?

How would one identify Peyronie's disease scar tissue? How would it feel and look?

Hard plaques: Thick hard palpable plaques with notebale curvature of the penis when you have an erection. Consult your physician for a definitive exam. ...Read more

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How do I identify Peyronie's disease scar tissue or plaque? And what is the difference between the 'scar tissue' and 'plaque'?

How do I identify Peyronie's disease scar tissue or plaque? And what is the difference between the 'scar tissue' and 'plaque'?

Same, but ...: Plaque is a specific descriptive term to denote the shape of the scar of Peyronie's disease, and scar tissue is a general term to describe the common microscopic picture of healing/healed tissue after injury by various reasons, resulting in disruption of local circulation and cell arrangement. The plaque may widely vary in size & shape so some plaques are barely palpable, and others, obvious. ...Read more

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What do my celiac disease tissue transglutaminase test results mean?

What do my celiac disease tissue transglutaminase test results mean?

Depends...: If the test was performed to identify whether you have celiac disease, an unequivocally elevated ttg value is diagnostic for celiac disease. If you are IgA deficient, and the only ttg assayed was iga, you may miss a diagnosis of celiac disease due to a falsely negative result. If you have celiac disease, ttg can be used to assess how compliant you may be with strict dietary gluten avoidance. ...Read more

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My penis has a very severe curve downwards starting at the base. I read about a disease involving scar tissue and there is none and no pain. ?

 My penis has a very severe curve downwards starting at the base. I read about a disease involving scar tissue and there is none and no pain. ?

Injury or Peyronies: You did not say how long this bend has been there. Assuming no injury , you are also a little young for Peyronies disease. However your best move is to go to a Urologist. There are several more questions that need an answer and whatever treatment if nec. ...Read more

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What do my celiac disease tissue transglutaminase iga/igg results mean?

What do my celiac disease tissue transglutaminase iga/igg results mean?

Anti-transglutaminas: Antibodies that bind to transglutaminase could indicate the presence of celiac disease. This is a sugggestive test only. Negative testing does not definitively rule-out celiac dz and positive testing does not confirm the diagnosis. An intestinal biopsy would be the most helpful test. ...Read more

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Is hughes disease a vascular disease or connective tissue disease? I forgot to ask rheumatologist when recently diagnosed.

Is hughes disease a vascular disease or connective tissue disease? I forgot to ask rheumatologist when recently diagnosed.

All: Hughes disease or antiphaspholipid synrome, has sticky blood causes clotting in unwanted places and time, due to thrombosis depending on the site causes variety of symptoms , TIA pe , deep vein thrombosis miscarriage etc could be immunological, as antiphaspho lipid antibodies are found , some times lupus also found in hughes syn. Warfarin is used ...Read more

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Is it normal to have CT scan say stable increased lobulated density in anterior superior mediastinum may represent residual disease vs thymic tissue?

Is it normal to have CT scan say stable increased lobulated density in anterior superior mediastinum may represent residual disease vs thymic tissue?

Mediastinum: Of course it depends on many factors. It's normal to see thymic tissue until early 20s is seen in fewer than 50% of people over 40. This density can be possibly be anything including normal, reaction to infection, thymic cysts, or hyperplasia from systemic disease. Fortunately it is stable, but a conversation with your doc and radiologist would be the best thing moving forward. ...Read more