Doctor insights on:
Diseases Of The Hypothalamus
Pituitary disease: The hypothalamus and pituitary work together to regulate many functions in the body, including hormonal regulation. Diseases can causes hormone deficiency or excess. Some of the hormones regulated are the thyroid, growth hormone, prolactin, (breastfeeding hormone) testosterone or estrogen, and cortisol. ...Read more
What can cause hypothalamic amenorrhea without stress/exercise/eating disorders? My hormone profile doesn't match pcos, but my periods are irregular.
Genetic defects: Genetic defects and chromosomal disorders are the main reason for hypothalamic disorders. Depending on the cause and the location of the lesions, there may be profound develpmental delay and hormonal deficiencies. Many of the pituitary hormones, such as oxytocin, adh, (vasopressin) and CRF will be absent and cause multi-system disorders. ...Read moreSee 1 more doctor answer
Varies: If encephalitis spreads to the hypothalamus it is hard to predict, because there are many nuclei or "centers" in the hypothalamus that do very different and sometimes opposite functions. For example some people with encephalitis lethargica slept constantly while others could not fall asleep at all, because different nuclei were affected. ...Read moreSee 1 more doctor answer
Yes, it surely can: There is considerable evidence that involvement of the hypothalamic-pituitary-adrenal axis can play a role in fatigue. Many ms patients do develop a variety of sleep disorders and a loss of hypocretin-i-secreting cells may be due to autoimmune mechanisms, perhaps enhancing daytime sleepiness. (seems some overlap with hla-dr-2 typing, as related to both ms and narcolepsy). ...Read more