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Doctor insights on: Discontinued Methotrexate

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Is arava (leflunomide) cheaper then methotrexate?

Is arava (leflunomide) cheaper then methotrexate?

Methotrexate cheaper: Generic Methotrexate is very inexpensive. If you get name brand pills it's more, but generic version of Arava (leflunomide) is more expensive than Methotrexate and Arava is the most expensive. In my experience, Methotrexate works better and has less frequent dosing (weekly instead of daily). I only use Leflunomide (arava) if Methotrexate can't be used for some reason. Side effects are similar. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Side effects of plaquenil (hydroxychloroquine) prescription?

Side effects of plaquenil (hydroxychloroquine) prescription?

A few: It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". There are others but these the most prominent. ...Read more

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Are imuran (azathioprine) tablets effective?

Are imuran (azathioprine) tablets effective?

Quite Effective: Imuran (azathioprine) is usually prescribed as an immune suppressant in transplant patients, for rheumatoid arthritis, crohn's and ulcerative colitis. It has been found to be quite effective in these conditions. ...Read more

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Having problems with hydroxychloroquin plaquenil (hydroxychloroquine) side effects?

Having problems with hydroxychloroquin plaquenil (hydroxychloroquine) side effects?

Side effects: Usual side effects are stomach upset and rahshes. Occ headaches. Take the med at lower dose with food and if you can't tolerate tne maximum dose it may still be effective. Vision problems are very rare these s[ecialist and get an opthalmology referral quickly. ...Read more

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On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.

On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.

Follow laboratory: You are correct that liver problems are risk with this regimen. Your physician needs to be certain that you are followed closely and correctly. Your own responsibility is to refrain from alcohol, and be certain no additional medicines you take do not worsen this risk. If you are concerned you need to discuss this with your physician. There are other therapy choices available. ...Read more

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Is dipentum (olsalazine) discontinued?

Is dipentum (olsalazine) discontinued?

Dipentum (olsalazine).: Not that i know of. Dipentum (olsalazine) isan anti-inflammatory medication used to treat ulcerative colitis. ...Read more

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Is cellcept (mycophenolate mofetil) a drug prescribed to treat dermatomyositis?

Is cellcept (mycophenolate mofetil) a drug prescribed to treat dermatomyositis?

Yes: Cellcept (mycophenolate mofetil) is an immunosuppressant drug used to treat a variety if conditions. In rheumatology it is most commonly used to treat certain types of lupus. Cellcept (mycophenolate mofetil) has been used successfully to treat dermatomyositis. It can help lower and or eliminate the steroid dose. ...Read more

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Is prednisone and humira (adalimumab) used together okay?

Is prednisone and humira (adalimumab) used together okay?

Yes, but............: Humira (adalimumab) should greatly reduce and even eliminate the need for prednisone, which is best used in rescue doses when arthritis flares! ...Read more

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Neoral (cyclosporine) 100 mg side effects and safety?

Neoral (cyclosporine) 100 mg side effects and safety?

THis is a brand of: Cyclosporine a. It is safe with monitoring of therapeutic drug levels. Side effects include renal insufficiency, hypertension, fluid retention and fine tremor. ...Read more

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Any methotrexate side effects?

Any methotrexate side effects?

Plenty : XX oral dos: Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european). The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid. ...Read more

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Dangers of plaquenil (hydroxychloroquine)?

Low risk: Potential Plaquenil (hydroxychloroquine) side effects include GI intolerance, itching, rash, muscle weakness and eye inflammation (retinopathy). All of these risks are very low and the benefits of Plaquenil (hydroxychloroquine) will far out weight the risks. ...Read more

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Drug interaction of humira (adalimumab) with niacin can taking niacin affect the effectiveness of humira (adalimumab)?

Drug interaction of humira (adalimumab) with niacin

can taking niacin affect the effectiveness of humira (adalimumab)?

No: Though interactions were reported in patients taking these two agents, Humira (adalimumab) and niacin, the patients were taking multiple other medications. It was not shown to be an interaction between the Niacin and humira (adalimumab). To test it individually, the Niacin could simply be stopped for a month assuming the Niacin was being used to treat hyperlipidemia. Ask your doctor if it is safe to hold the niacin. ...Read more

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Any side effects from rituxan (rituximab) therapy?

Any side effects from rituxan (rituximab) therapy?

Mostly infusion rxns: Rituxan is given intravenously slowly at first to look for common immediate reactions like chills, fever, shakes, itching, hives, headache all of which could be prevented or lessened by giving premedications like Benadryl (diphenhydramine) and steroids. Reactivation of hepatitis b, lowering resistance to infections, rapid destruction of tumor cells causing i'll effects to organs (tumor lysis) can also occur. ...Read more

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Side effects and effectiveness of orencia (abatacept) mediCation?

Side effects and effectiveness of orencia (abatacept) mediCation?

Watch for infections: Orencia (abatacept) is approved to treat moderate to severe rheumatoid arthritis. Typically it is prescribed when disease modifying anti rheumatic drugs (DMARDS) are not effective. The most common DMARD is methotrexate. Orencia (abatacept) is usually prescribed in combination with methotrexate but sometimes is given alone. Orencia (abatacept) is quite effective for many but not all people. It's main side effect: infections. ...Read more

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Can methotrexate make you sick?

Can methotrexate make you sick?

Methotrexate: The side effects of Methotrexate include liver dysfunction, increased risk of infection, blood count abnormalities, fatigue on the day of treatment and gastrointestinal distress. ...Read more

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How well does methotrexate work?

How well does methotrexate work?

Need more info: Methrotrexate is used for many diseases. Please ask this question again and be specific about what the Methotrexate is being used for. ...Read more

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Does methotrexate make u gain weight?

Does methotrexate make u gain weight?

No!: MTX does not cause weight gain, although arthritis through lower physical activity can! ...Read more

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Is it o.K. To tan while on methotrexate?

No: While this is actually unlikely to cause problems, sunburn may be more likely while using methotrexate. Though it may depend on why and how you're using it. ...Read more

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What are signs of methotrexate intoxicty?

Many: Methotrexate toxicity can take many forms, from extreme mucositis, low blood counts, and kidney damage. If Methotrexate is given intrathecally (into spinal csf) as is done to treat leukemia, it can sometimes cause toxicity to the brain, which can manifest itself as seizures. Methotrexate can also affect the liver and lungs. If you are having new symptoms, talk with the prescribing doctor. ...Read more

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Please describe the medication: methotrexate?

Standard therapy: Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA and other rheumatologist diseases. ...Read more

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What is methotrexate and what is it used for?

See below: It is what is known as a dmard---disease modifying anti-rheumatic drug that is used to treat autoimmune diseases such as rheumatoid arthritis. ...Read more

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My friend is pergenant, can use methotrexate?

No: Methotrexate can cause serious birth defects. If she is pregnant and is taking methotrexate, she needs to notify her prescribing physician and her OB and stop the medication. ...Read more

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What dosage for methotrexate tablets are safe?

Up to 25 mg weekly: Standard Methotrexate doses for RA and rheumatologic diseases are up to 25 mg weekly. With any dose of methotrexate, routine lab studies are necessary to screen for side effects. ...Read more

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How long does methotrexate stay in your system?

Not enough data: Methotrexate has a half life of 15 hours. It should be totally gone from the blood fairly quickly but can remain in the liver longer. We do not have human studies to say how long that it. ...Read more

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Is longterm use of methotrexate relatively safe?

Yes: Mtx appears to be safe for long term use if side effects are mild. However, many patients have other treatments in addition to mtx which may affect levels and require monitoring for toxicity, . ...Read more

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How much time will I have to be on methotrexate?

Not enough info: Why are you taking it? What is it intended to treat? Provide specifics if you want an answer. ...Read more

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How long does methotrexate stay in your body for?

It lasts: @ and one half months for it and its polyglutamates to leave your body. We tell women desiring pregnancy to wait for three months. ...Read more

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How long does methotrexate stays in your body for?

How long does methotrexate stays in your body for?

3-4 weeks: That is difficult to answer. The half life of Methotrexate is only 15 hours but it remains in the liver longer. I would say it would be gone in 3 weeks or so. ...Read more

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Can I take other medicines if I take methotrexate?

Yes : We use it with a lot of different medications. Whenever you take Methotrexate you need to be monitored. We advise no alcohol because alcohol plus Methotrexate increases the risk of liver disease. ...Read more

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Can you tell me about having the methotrexate shot?

See details: It is given as a subcutaneous injection, similar to an insulin shot. The discomfort is very minimal. If you have any other questions, list them. ...Read more

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For what length of time can methotrexate make you sick?

See details: What do you mean by sick? If you mean GI problems such as nausea and vomiting, it may last a few days. I would suggest that the Methotrexate be given by injection subcutaneously instead of by mouth. It is easy to do and will avoid GI issues. It may also be more effective this way. ...Read more

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Do you have information on methotrexate uses and effects?

Many and quite safe!: Mtx is used in many autoimmune diseases with great effect. The drug is given IV in high doses to treat cancer. In much lower doses, given subcutaneously like insulin, with fewer side-effects than the same oral dose, does not go to the liver. And you absorb 100%, not the 40-90% when taken by mouth. Great drug. Ist line in ra! ...Read more

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What would weekly methotrexate injections do to a person?

What would weekly methotrexate injections do to a person?

A mainstay for...: The treatment of rheumatoid arthritis and psoriatic arthritis, and other inflammatory conditions! i administer to my patients mtx by the subcutaneous route, thereby insuring 100% absorption and bypassing stomach and liver. When given with folic acid, i rarely see significant problems for my patients! ...Read more

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Can specific nutrition / diet help people on methotrexate?

Can specific nutrition / diet help people on methotrexate?

Add folate (folic acid): http://www.rheumatology.org/practice/clinical/patients/medications/methotrexate_(rheumatrex, _trexall)/ also check out mayoclinic.Com search folate (folic acid) and methotrexate. ...Read more

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Dr. Robert Lowe
340 doctors shared insights

Rheumatrex (Definition)

Rheumatrex ...Read more