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Doctor insights on: Direct Bilirubin

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Dr. Ana Adelstein
39 Doctors shared insights

Direct Bilirubin (Overview)

Bilirubin - direct, indirect, and total provide some clues to the underlying disease process. The direct bilirubin has to processed further by the liver for excretion out of the body. Therefore, the direct bilirubin level is generally used as an indicator for the function and health of the liver.


Dr. Ana Adelstein
39 Doctors shared insights

Direct Bilirubin (Overview)

Bilirubin - direct, indirect, and total provide some clues to the underlying disease process. The direct bilirubin has to processed further by the liver for excretion out of the body. Therefore, the direct bilirubin level is generally used as an indicator for the function and health of the liver.


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Direct bilirubin is 1 and indirect is 1. what does it mean?

Likely liver damage: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your direct bilirubin is higher than normal and represents intra-hapatic obstruction to the flow of bile. You have listed a number of liver disorders and any of those could explain these results as could the medications. ...Read more

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Direct bilirubin. 2, ALT 69, alkaline phosphatase 156, total chol. 213. Sludge on us hida scan 40% still have pain on right side only 18. Bad?

Direct bilirubin. 2, ALT 69, alkaline phosphatase 156, total chol. 213. Sludge on us hida scan 40% still have pain on right side only 18. Bad?

Only 18?: Abnormal alt is most commonly a sign of fatty liver disease. Other causes of hepatitis should be ruled out. Follow-up with your physician to get proper follow-up testing. Good luck! ...Read more

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Month old with high direct bilirubin? They say it's from my breastfeeding?

Maybe: It depends on how high the 'high level' is, and how healthy your baby is, better if the baby was full term, not as good if the baby is a premie. In general dr. S get worried when the level is near 20. It would be unusual for a level this high with a month old infant. There are 'baby metabolic factors' that are possible too. Have your doctor explain the evaluation process and tell you just how high. ...Read more

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Elevated indirect bilirubin, normal direct bilirubin, low red blood cell count, normal white blood cell count, iron overload (83), enlarged spleen?

Elevated indirect bilirubin, normal direct bilirubin, low red blood cell count, normal white blood cell count, iron overload (83), enlarged spleen?

Need more informatio: We can not comment on these blood tests without knowing your hemoglobin and hematocrit andtotal rbc level. Total iron, iron binding capacity and most important ferritin level
also need to know the values of liver enzymes;level of indirect bilirubin
i suggest you consult your doctor who may have all this information and can tell you if anything needs to be done or just follow up. ...Read more

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Direct bilirubin 4 out of (0-3.4) is this normal?

What units?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, if the direct bilirubin is 4.0 mg/dL it is not normal. ...Read more

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Direct bilirubin is 1 and indirect is 1. what does it mean?

Likely liver damage: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your direct bilirubin is higher than normal and represents intra-hapatic obstruction to the flow of bile. You have listed a number of liver disorders and any of those could explain these results as could the medications. ...Read more

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What is the definition or description of: direct bilirubin?

What is the definition or description of: direct bilirubin?

Direct bilirubin: Bilirubin - direct, indirect, and total provide some clues to the underlying disease process. The direct bilirubin has to processed further by the liver for excretion out of the body. Therefore, the direct bilirubin level is generally used as an indicator for the function and health of the liver. ...Read more

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My direct bilirubin is 0.9, so is that still normal (i have no ill problems)?

My direct bilirubin is 0.9, so is that still normal (i have no ill problems)?

Number of factors:: If you have a barely elevated bilirubin, bot normal liver enzymes, I would not be concerned. However, if were the opposite I would be concerned.

However, 5% of american's have gilbert's sydrome, which causes mild bilirubin elevations, which dp no harm. I have it! ...Read more

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What does this test result mean? Direct bilirubin 0.6

Elevated: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your direct bilirubin level is elevated indication liver issues. Please see your doctor. You may consult this site for more info.

https://www. Nlm. Nih. Gov/medlineplus/ency/article/003479.htm ...Read more

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My total bilirubin is 1.5 and the direct bilirubin is 0.3 what does it mean?

My total bilirubin is 1.5 and the direct bilirubin is 0.3 what does it mean?

In most labs: A total bili of 1.5 is upper normal or very slightly elevated. In and of itself not a big deal. ...Read more

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My total bilirubin is 1.30 and direct bilirubin is 0.43 is it in normal range or need to worry?

Probably okay.: This set of results may be a sign of what is called Gilbert's syndrome, which is not a significant problem, although one would need to see the rest of the liver tests to have a better idea of what is really going on. I would ask your primary doctor to interpret them for you. Good luck. ...Read more

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My total bilirubin 2.06 and direct bilirubin 0.36 and indirect bilirubin 1.70 is this normal for me or what?

High bilirubin: If every other test is normal, only bilirubin elevated especially in the fasting blood work, is nothing need to worry about, it is benign problem, no specific treatment is indicated. ...Read more

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I have taken bilirubin and sgpt test twice My sgpt was earlier 40 and it reduced to 31 But direct bilirubin has increased and indirect is reduced?

Sgpt is normal.: What was the value of your total bilirubin? No values depending on the lab are 0.3-1.0 mg/dl. If that was normal, no need to worry about indirect or direct. If indirect is high one worries about excessive breakdown of red blood cells (hemolysis)ex bleeding, hemolytic anaemia etc. If direct is elevated, there's concern for liver blockage. ...Read more

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My direct bilirubin was 0.8, after 1 week is 1.15 Indirect was 0.8, after 1 week is 0.25 Sgpt is normal What should I do? Why direct is increasing?

Time for workup: If this is new, stop all the medications you don't truly need, including "holistic" and "Ayurvedic" and repeat the labs in two weeks. If other liver function tests are abnormal, your physician will order labs and perhaps a biopsy. You may be tested for antimitochondrial antibodies as well as more familiar like hep B & C, urinary copper, serum ferritin, others. ...Read more

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Can gilbert's also present with mildly elevated direct bilirubin (0.4-0.7). with elevated total (1.4-2.2) Mostly indirect still some direct elevation?

Not from Gilbert's: Gilbert's syndrome causes a deficiency in the enzyme that converts indirect bilirubin to direct bilirubin. In other words, the only issue is that indirect bilirubin is converted to direct bilirubin more slowly. People with Gilbert's are not unhealthy from it and are not considered to have a "disease." If direct bilirubin is elevated, something else is going on. ...Read more

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Hi my liver test total bilrubin 1.7 direct bilirubin 0.6 and indirect bilirubin 1.1 all other are normal can I take acholal or not?

Hi my liver test total bilrubin 1.7 direct bilirubin 0.6 and indirect bilirubin 1.1 all other are normal can I take acholal or not?

Don't Rx labs: You indicate that you have a history of known liver disease. You need to learn the cause. With mixed direct and indirect being high, this is almost certainly intrinsic liver disease and this is serious. But you ask only, "can I drink alcohol? " if alcohol is the cause of your liver disease, this is a suicide course. If not, you need to find what's wrong with your liver ; seek rx, alcohol-free. ...Read more

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Direct bilirubin level high - is that from my gall bladder?

Direct bilirubin level high - is that from my gall bladder?

ItCanBeINDIRECTLY:-): Jaundice is the medical term for an elevated bilirubin level in the bloodstream; this is a breakdown product of red blood cells, normally excreted via the liver into the digestive tract. Total bilirubin levels consist of direct+indirect. Elevated direct bili can occur from any liver disease or obstruction of the outflow of bile from the liver, which can occur when a stone blocks the bile duct. ...Read more

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Month old with high direct bilirubin? They say it's from my breastfeeding?

Maybe: It depends on how high the 'high level' is, and how healthy your baby is, better if the baby was full term, not as good if the baby is a premie. In general dr. S get worried when the level is near 20. It would be unusual for a level this high with a month old infant. There are 'baby metabolic factors' that are possible too. Have your doctor explain the evaluation process and tell you just how high. ...Read more

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Total bilirubin 4.5. Direct bilirubin 0.9. All other liver functioning tests are normal. Why?

See below: Increased indirect bilirubin caused by overproduction of bilirubin (breakdown product of red blood cells), reduced bilirubin uptake, or impaired bilirubin conjugation. Many causes, but in absence of other symptoms and a history of elevated bili in past this is likely a benign genetic disorder. However, there are other potential causes and you should see your doc to make sure. ...Read more

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High total and direct bilirubin - but two fibroscans state no liver disease. What's going on, here?!

High d bili alone: When the only abnormality on thorough workup including liver function tests & liver scans is a high direct bilirubin making up approximately 50% of the total bilirubin, the diagnosis usually made is Rotor or Dubin-Johnson syndrome, rare but harmless inherited conditions. If there are any other abnormalities on tests or exam, or if medical history suggests otherwise, then many other possibilities. ...Read more

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Total bilirubin- 4.5 direct bilirubin- 0.3. Is this ok? Liver functioning all normal other than that

Gilbert's syndrome: Yes. This is very consistent with gilbert's. In the us, approximately 3-7% of the population has gilbert's. Typically patients with gilbert's will have a total bilirubin <6 (like you). It can fluctuate and worsen during times of illness, stress or dehydration. It will not negatively affect your health. ...Read more

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Does this combination indicate anything significant: Low Total & Direct Bilirubin combined with High AST?

Does this combination indicate anything significant: Low Total & Direct Bilirubin combined with High AST?

Can't really tell: Lab results usually are numbers, and numbers are just numbers, without much meaning unless a doctor takes in the whole picture of what's going on with his patient. If the patient's AST (an enzyme, whose level is being measured in a blood sample) is higher than the normal range, the doctor who ordered the test may or may not consider the lab result a problem, depending on how high it is, etc... ...Read more

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Direct bilirubin is 0.3 (rangeis 0-0.2), globulin-3.6 (range is 2.3-3.5) a/g ratio is 1.19 (range-120-2). Cbc is normal. Plz advise

Get with your doctor: The only concern I have here is the slight elevation in direct bilirubin. I'm also going to assume it's new; some folks always run it at this level because of their biology. It won't hurt you but may be a warning, most likely that some medication giving you cholestasis. ...Read more

Bilirubin (Definition)

Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more