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Doctor insights on: Diphenhydramine Withdrawal

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Do people experience withdrawals from using diphenhydramine to get high?

Do people experience withdrawals from using diphenhydramine to get high?

I doubt it: Why take an antihistamine to get high? I have seen it precipitate seizures and it usually makes people very drousey and some children get very hyper ... After a period of time tachyphyllaxis may occur anyway you will stop itching and the aalergies will clear up. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Are there withdrawal symptoms from diphenhydramine?

Are there withdrawal symptoms from diphenhydramine?

Benedryl side effect: No. Withdrawl symptoms are related to a body's reaction after cessation of exposure to an addictive substance. Benedryl=dyphenhydramine is not an addictive substance, so withdrawl would not be medically anticipated. You may have rebound swelling of the sinus tissues that had been treated by the antihistamine. ...Read more

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Do people have withdrawals from stopping benadryl?

Do people have withdrawals from stopping benadryl?

benadryl: Depending on the reason you are taking benadryl, if you have grown dependent on it as a sleep aid, it may be a problem to fall asleep without anything. If taken to treat allergies, symptoms will recur. There are no withdrawal symptoms per se. ...Read more

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Is diphenhydramine hc1 50 addictive?

Is diphenhydramine hc1 50 addictive?

No: Diphenhydramine helps restless and anxiety through it's antihistamine activity, much like vistaril. It is not addictive, but if you are taking it several times daily you could find yourself having some withdrawal symptoms like runny nose. ...Read more

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If I have been taking two diphenhydramine hydrochloride 25 mg pills everynight for over a year, and i stop taking it cold turkey, will i withdraw?

If I have been taking two diphenhydramine hydrochloride 25 mg pills everynight for over a year, and i stop taking it cold turkey, will i withdraw?

No: While it may take you a while to get to used to falling to sleep without the diphenhydramine, you will have no withdrawal symptoms if you abruptly stop taking the medicine. Some people have had good success using melatonin (3 mg) as a substitute. This is available over the counter. ...Read more

Dr. Michael Rupp
996 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Withdrawal (Definition)

Symptoms upon abrupt discontinuation or decrease in intake of substances such as ...Read more