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Doctor insights on: Diphenhydramine Warnings And Recalls

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Can you really die from an overdose of diphenhydramine?

Can you really die from an overdose of diphenhydramine?

Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read more

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Dr. Michael Rupp
996 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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What amount diphenhydramine is an overdose?

What amount diphenhydramine is an overdose?

It depends: Diphenhydramine was a major cause of seizures reported to a poison center. At a dose of 7.5mg/Kg (a total dose of 500 mg [20 OTC tablets] for a 150 pound person) many p0eople will develop severe reactions. In doses over 1g (40 tablets) the drug may be lethal. ...Read more

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Can I take 75mg of Diphenhydramine HCI?

Can I take 75mg of Diphenhydramine HCI?

Probably but why?: Adult dosing is 25-50 mg every 4-6 hours as needed. Maximum dosing is listed as 100mg per dose up to a total of 300 to 400mg per day. I'm just wondering your reason for taking 75mg, as this medicine is sedating, and can make you sleepy. If the 25-50 mg isn't strong enough, maybe there's something else better for you to try. Discuss this with your doctor, who might have a better suggestion for you. ...Read more

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Had 100mg of diphenhydramine last night at 10PM. Is it normally safe to take that dose two nights in a row?

Yes: THe maximum daily dosage of diphenhydramine is 400mg/day However, the recommended dosage of the medication for insomnia is 50mg at night. Would recommend to reduce the dosage to 50mg at night Please see your doctor if still have issues with insomnia. ...Read more

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Can you please describe the effects and factors of taking over 22 pills of diphenhydramine hci 25 mg?

Can you please describe the effects and factors of taking over 22 pills of diphenhydramine hci 25 mg?

Wow: Is this a suicidal attempt? If so , see a psychiatrist asap. The short answer would be excessively dry mouth, fast heart rate, constipation, urinary retention, and drowsiness from its anticholinergic actions. ...Read more

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Is diphenhydramine adictave?

No: The antihistamine is does not have addictive qualities. Yet a person can become habit driven to continue any product/medication/coffee/food etc.Habituation is a strong force in ones life to continue past patterns. If stopped, a longing for that product can be quite strong, but it does not produce the physical addiction entails. ...Read more

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What are the effects of diphenhydramine od?

What are the  effects of diphenhydramine od?

Dangerous Effects: Although death by Diphenhydramine overdose is uncommon, dangers associated with an overdose include cardiac arrhythmias, delirium, respiratory suppression, short-term memory loss, and urinary retention. If you suspect Diphenhydramine overdose, contact emergency services (911). There is an antidote that can be administered by medical professionals in the emergency room. ...Read more

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What is the lethal dose of diphenhydramine for a 110 pound woman?

Therapeutic dose: The therapeutic dose is 1mg/kg. Would be ~ 50mg. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more