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Doctor insights on: Diphenhydramine Safety Glaucoma

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Why is diphenhydramine contraindicated in narrow angle glaucoma?

Why is diphenhydramine contraindicated in narrow angle glaucoma?

It can increase IOP: http://answers.yahoo.com/question/index?qid=20090328145710aa3jfbq it has anti-cholinergic properties that can cause intra-ocular pressure in the eye to increase, due to obstruction of the normal flow of fluid out of the eye. The link above explains it in more detail. ...Read more

Dr. Cornelia Franz
2,007 doctors shared insights

Safety (Definition)

Safety is a topic that includes recommendations for making the home and outdoor environments safe, especially for kids. This topic includes ideas on childproofing cabinets, keeping dangerous items locked up, ensuring balconies and stairs are safe, covering wiring and outlets, fencing off pools, staying away from cars, watching ...Read more


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Is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma, and pregnancy? Why?

Is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma, and pregnancy? Why?

Anti-cholinergic : Diphenhydramine's anticholinergic effects are to blame. They cause it to aggravate increased intraocular pressure, and dry secretions in those having asthma attacks, making it hard to clear secretions. Here's a link: http://answers.Yahoo.Com/question/index?Qid=20090328145710aa3jfbq the link is wrong about pregnancy, though. It's category b, not c, for pregnancy and considered safer than other meds. ...Read more

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Is it true that diphenhydramine is contraindicated in narrow angle glaucoma, acute asthma and pregnancy?

Is it true that diphenhydramine is contraindicated in narrow angle glaucoma, acute asthma and pregnancy?

DPH & Asthma, glauco: Diphenhydramine(dph), benadryl, (diphenhydramine) is an antihistaminic having an Atropine like effect, i.e. In asthma is dries up secretions in the bronchi ( the respiratory pipes), thus it worsens asthma. In glaucoma it can precipitate an acute angle closure glaucoma, yes it is unwise to use it. On other side effect is lethargy and in pregnancy it is also unwise to unnecessarily sedate the fetus. So, yes yes yes. ...Read more

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Please explain why is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma and pregnancy?

Please explain why is diphenhydramine contraindicated in narrow angle glaucoma, acute asthma and pregnancy?

Side effects: Antihistamines like Diphenhydramine have side effects that effect a certain part of the nervous system (cholinergic) which would cause bronchoconstriction, and further closing of the "angle" in glaucoma (angle closure type). If you must take an antihistamine, speak to your physician about antihistamines that do not or minimally affect this system. Good luck. ...Read more

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I found out I am allergic to peanuts after having a anaphylactic shock. If I take Benadryl (diphenhydramine) first can I still eat peanuts safety?

I found out I am allergic to peanuts after having a anaphylactic shock. If I take Benadryl (diphenhydramine) first can I still eat peanuts safety?

No: just avoid peanuts, keep an antihistaminic like benadryl (diphenhydramine) handy in case you eat peanuts by mistake, also you need to keep an epinephrine pen,the only treatment so far is avoidance of peanuts or any food that contains them, perhaps depends on the degree of sensitization, some patients can tolerate a small amount, others would react even to the smell,please c an allergist for assessment and follow up ...Read more

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Can i cut diphenhydramine in half?

Can i cut diphenhydramine in half?

Depends: Some Diphenhydramine comes in capsules and some in solid pills. You can cut the pills but the capsules will just squish, break open and spill the contents. If capsules are all you have, you can dissolve the contents in water and drink half or something we do with patients at times is to mix it with jello and have them eat the proper amount. ...Read more

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Can i cut a diphenhydramine in half?

Tabs, yes: It is not practical to cut a capsule, but a scored tablet can be easily cut with a pill cutter. There are many formulations of Diphenhydramine in case a lower than usual dose is required. ...Read more

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What color are diphenhydramine pills?

DiphenhydramineColor: Usually they are pink or pink and white if capsules; but I do not know if soem generic version scould be white. ...Read more

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Can I take 75mg of Diphenhydramine HCI?

Can I take 75mg of Diphenhydramine HCI?

Probably but why?: Adult dosing is 25-50 mg every 4-6 hours as needed. Maximum dosing is listed as 100mg per dose up to a total of 300 to 400mg per day. I'm just wondering your reason for taking 75mg, as this medicine is sedating, and can make you sleepy. If the 25-50 mg isn't strong enough, maybe there's something else better for you to try. Discuss this with your doctor, who might have a better suggestion for you. ...Read more

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What amount diphenhydramine is an overdose?

What amount diphenhydramine is an overdose?

It depends: Diphenhydramine was a major cause of seizures reported to a poison center. At a dose of 7.5mg/Kg (a total dose of 500 mg [20 OTC tablets] for a 150 pound person) many p0eople will develop severe reactions. In doses over 1g (40 tablets) the drug may be lethal. ...Read more

Dr. Robert Chang
1,018 doctors shared insights

Glaucoma (Definition)

Glaucoma refers to a group of eye conditions that lead to damage to the optic nerve, the nerve that carries visual information from the eye to the brain. In many cases, damage to the optic nerve is due to increased pressure in the eye, also known ...Read more


Dr. John Chiu
1,011 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more