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See a doctor now!: Dphm (aka benadryl): "severe" symptoms occur at the critical dose limit of 1 gram=1000mg. Although the frequency of delirium/psychosis, coma and seizures can occur. "moderate" symptoms (300mg or more) include isolated & spontaneously resolving agitation, confusion, hallucinations & ekg abnormalities. It is metabolized via cytochrome p450 2d6 isoenzyme in the liver. ...Read more
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Accidentally give my liver too much? Had 1/4 glass of wine. Then 3 hrs later, not thinking, took a Benadryl for allerg and 25 mg of prs Zoloft for anx
Liver likely ok: Although alcohol, Benadryl (diphenhydramine), and Zoloft (sertraline) are all broken down by the liver, the quantities you mention shouldn't be a problem for an otherwise healthy liver. But I'm a little concerned if you take Zoloft "prn" (as needed) for anxiety. It doesn't work well that way, although it can relieve anxiety if taken daily. Talk to your prescribing doctor about this. ...Read moreSee 1 more doctor answer
I take benadryl everyday about 250mg not at once but during the day for chonic allergies. Been doing this for two years will this damage my liver?
No, but...: That is really a lot of benadryl and while it will not damage your liver it can have a lot of side effects such as fatigue, dry mouth, constipation and mental slowing. Discuss a change to a non-sedating antihistamine, nasal saline and some nasal steroids with your doctor and try to get off this large dose of benadryl. Singulair may also be helpful. ...Read moreSee 1 more doctor answer
Since my friend took Benadryl and Mucinex i just want to make sure she isn't going to have a hear attack or her liver shut down. It wasn't a suicide.
Hi I took a regular Benadryl (Non drowsy) about an hour ago and I'm wanting to know that if I drink wine tonight could that hurt my liver?
Unlikely: Not really a significant interaction.Get a more detailed answer ›
I've had trouble falling asleep and waking up for as long as I can remember. Currently I take 200mg of Benadryl nightly to sleep. Worried about liver?
I have liver disease from overdosing on Tylenol (not treated) benadryl and xanax in teen years, how is this treated/managed?
More informaton: There are blood tests that can indicate liver damage. This information would be needed. Benadryl and Xanax would be unlikely to contribute to liver damage. Tylenol might, but it would depend on the dose. You need medical verification of liver damage; and then the question of treatment can be addressed. ...Read more
Been taking diphenhydramine HCL for about 10 years in high doses. I have recently stopped taking them. The itching is intense. HOW CAN I STOP THE ITCH?
Many side effects: The Diphenhydramine can cause sleepiness, dry mouth, problems urinating. It can also raise up your blood pressure. Phenylephrine can cause higher blood pressure, speed up your heart rate(pulse rate). Cause palpitations, rapid heart beat. It can also make you feel nervous and anxious. It can also cause dry mouth. Using more that 3 grams of acetominophen per day is bad for your kidneys and liver. ...Read more
Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read moreSee 1 more doctor answer
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