Top
10
Doctor insights on: Diphenhydramine Interactions

Share
1

1
Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

No: I am not sure what l-theanine is. However, the only dietary supplements/herbals i know of which should be avoided when taking Diphenhydramine are valerian, st. John's wort, kava kava, and gotu kola; as the combination may enhance CNS depression. I am doubtful that whatever l-theanine is will compound any sedative effects you may experience with Diphenhydramine alone. ...Read more

Dr. Michael Rupp
996 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


2

2
Is it safe to take Pseudophedrine and Diphenhydramine together? Medscape says significant interaction but other sources say no interaction.

Is it safe to take Pseudophedrine and Diphenhydramine together? Medscape says significant interaction but other sources say no interaction.

OK to take together: Diphenhydramine is benadryl, which is an antihistamine. Many antihistamines are taken together with decongestants such as pseudoephedrine. Diphenhydramine can help itching, sneezing, swelling, whereas Pseudoephedrine can help nasal congestion. Common antihistamine/decongestant combos include loratadine-D, cetirizine-D, fenofexadine-D. ...Read more

See 1 more doctor answer
4

4
Are there any drug interaction with inderal and diphenhydramine?

Are there any drug interaction with inderal and diphenhydramine?

No: There are no significant interactions between these two drugs. They are safe to take together. ...Read more

See 1 more doctor answer
6

6
Interaction between Synthroid and sleep-eze (diphenhydramine hydrochloride) ?

No significant: Medication interactions were noted when using a drug interaction checker. But that is never a 100% guarantee. ...Read more

8

8
Can you really die from an overdose of diphenhydramine?

Can you really die from an overdose of diphenhydramine?

Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read more

See 1 more doctor answer
9

9
What amount diphenhydramine is an overdose?

It depends: Diphenhydramine was a major cause of seizures reported to a poison center. At a dose of 7.5mg/Kg (a total dose of 500 mg [20 OTC tablets] for a 150 pound person) many p0eople will develop severe reactions. In doses over 1g (40 tablets) the drug may be lethal. ...Read more

10

10
Can I take 75mg of Diphenhydramine HCI?

Probably but why?: Adult dosing is 25-50 mg every 4-6 hours as needed. Maximum dosing is listed as 100mg per dose up to a total of 300 to 400mg per day. I'm just wondering your reason for taking 75mg, as this medicine is sedating, and can make you sleepy. If the 25-50 mg isn't strong enough, maybe there's something else better for you to try. Discuss this with your doctor, who might have a better suggestion for you. ...Read more

See 1 more doctor answer

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more