Doctor insights on:
Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?
No: I am not sure what l-theanine is. However, the only dietary supplements/herbals i know of which should be avoided when taking Diphenhydramine are valerian, st. John's wort, kava kava, and gotu kola; as the combination may enhance CNS depression. I am doubtful that whatever l-theanine is will compound any sedative effects you may experience with Diphenhydramine alone. ...Read more
Is it safe to take Pseudophedrine and Diphenhydramine together? Medscape says significant interaction but other sources say no interaction.
OK to take together: Diphenhydramine is benadryl, which is an antihistamine. Many antihistamines are taken together with decongestants such as pseudoephedrine. Diphenhydramine can help itching, sneezing, swelling, whereas Pseudoephedrine can help nasal congestion. Common antihistamine/decongestant combos include loratadine-D, cetirizine-D, fenofexadine-D. ...Read moreSee 1 more doctor answer
The question presented in this thread is about INTERACTION between Diphenhydramine and Loratadine, NOT the additive effects. Is there chemical interac?
No: to best of my knowledge there is no chemical interaction between the two except additive effect ...Read more
No: No problem.Get a more detailed answer ›
Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read moreSee 1 more doctor answer
Probably but why?: Adult dosing is 25-50 mg every 4-6 hours as needed. Maximum dosing is listed as 100mg per dose up to a total of 300 to 400mg per day. I'm just wondering your reason for taking 75mg, as this medicine is sedating, and can make you sleepy. If the 25-50 mg isn't strong enough, maybe there's something else better for you to try. Discuss this with your doctor, who might have a better suggestion for you. ...Read moreSee 1 more doctor answer
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