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Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read moreSee 1 more doctor answer
Probably but why?: Adult dosing is 25-50 mg every 4-6 hours as needed. Maximum dosing is listed as 100mg per dose up to a total of 300 to 400mg per day. I'm just wondering your reason for taking 75mg, as this medicine is sedating, and can make you sleepy. If the 25-50 mg isn't strong enough, maybe there's something else better for you to try. Discuss this with your doctor, who might have a better suggestion for you. ...Read moreSee 1 more doctor answer
Had 100mg of diphenhydramine last night at 10PM. Is it normally safe to take that dose two nights in a row?
Can you please describe the effects and factors of taking over 22 pills of diphenhydramine hci 25 mg?
No: The antihistamine is does not have addictive qualities. Yet a person can become habit driven to continue any product/medication/coffee/food etc.Habituation is a strong force in ones life to continue past patterns. If stopped, a longing for that product can be quite strong, but it does not produce the physical addiction entails. ...Read more
Dangerous Effects: Although death by Diphenhydramine overdose is uncommon, dangers associated with an overdose include cardiac arrhythmias, delirium, respiratory suppression, short-term memory loss, and urinary retention. If you suspect Diphenhydramine overdose, contact emergency services (911). There is an antidote that can be administered by medical professionals in the emergency room. ...Read more
Therapeutic dose: The therapeutic dose is 1mg/kg. Would be ~ 50mg. ...Read more
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