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Doctor insights on: Diphenhydramine For Anxiety

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Is it ok to take one 25MG Benadryl (diphenhydramine) for anxiety regularly?

Is it ok to take one 25MG Benadryl (diphenhydramine) for anxiety regularly?

OK but: There are better alternatives. Talk to your doctor. Benadryl (diphenhydramine) tends to make you just drowsy. ...Read more

Dr. Heidi Fowler
3,281 Doctors shared insights

Anxiety (Definition)

Anxiety is a general term for several disorders that cause nervousness, fear, apprehension, and worrying. These disorders affect how we feel and behave, and they can manifest real physical symptoms. Mild anxiety is vague and unsettling, while severe anxiety can be extremely debilitating, having a serious ...Read more


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Can I take doxylamine or diphenhydramine for anxiety or should I ask my dr about atarax (hydroxyzine)?

Can I take doxylamine or diphenhydramine for anxiety or should I ask my dr about atarax (hydroxyzine)?

Ask your doctor: You should notify your doctor that you are having difficulty with anxiety and get his or her advice about treatment. ...Read more

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Does Benadryl (diphenhydramine) work for anxiety?

Does Benadryl (diphenhydramine) work for anxiety?

Time For DroolSchool: We here on the ranch call it"Benadrool"because it can shlog you out. So yes sometimes it can work for calming down. But too much turns it into Bena-DryMouthBlurredVisionKnockedOut-Dryl. So just take one capsule (25mg)or at most 50mg. It's not usually prescribed for this. There are other medications specifically for anxiety. But Benadryl (diphenhydramine) is a non-prescription medication and usually safe at proper doses ...Read more

Dr. Alan Ali Dr. Ali
1 doctor agreed:
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Is it okay for me to take Benadryl (diphenhydramine) for some anxiety issues I am having?

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Anxiety: On an as needed basis, short term, is ok. Also talk to your doctor about other options for anxiety long-term if needed. ...Read more

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Is there a difference between diphenhydramine and hydroxyzine for anxiety?

Is there a difference between diphenhydramine and hydroxyzine for anxiety?

Diphenhydramine?: People have a tendency to take benadryl- diphenhydramine for sleeplessness. Ideally is not the good medicine for anxiety. Side effects are more. Has some effects on the central nervous system, can cause confusion -especially in elderly people, mouth dryness, fast heart rate, urinary retention -more evident in elderly men with big prostate glands. We call this as anticholinergic effect. Hydroxine-ok ...Read more

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Is it safe to take Benadryl (diphenhydramine) every night for anxiety?

Is it safe to take Benadryl (diphenhydramine) every night for anxiety?

Benadryl (diphenhydramine): Benadryl (diphenhydramine) is not an anti-anxiety medication. People take it for its drowsiness side-effect. It will not relieve your anxiety whatsoever. ...Read more

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Me Benadryl (diphenhydramine) & Nexium for my anxiety and panic disorder, i, what are the side effects?

Me Benadryl (diphenhydramine) & Nexium for my anxiety and panic disorder, i, what are the side effects?

It sounds like the: Anxiety has negatively effected your GI tract, which explains the use of nexium. Nexium can cause headache, nausea and diarrhea commonly and low magnesium levels and may effect how other medicines work. Benadryl (diphenhydramine) is an antihistamine which can cause headache, diarrhea, dizziness, drowsiness and other side effects. ...Read more

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Does diphenhydramine work for stress, and anxiety?

Does diphenhydramine work for stress, and anxiety?

Maybe: But it is not meant for stress or anxiety, it can cause some sedation, hence the feeling of relaxation, but loses this effect fast due to tolerance, ...Read more

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Hello, I took one Benadryl (diphenhydramine) at 8:08 pm and I'm assuming it has kicked in but I'm really tired but full of anxiety... How much more longer will the "high" be gone?

Hello, I took one Benadryl (diphenhydramine) at 8:08 pm and I'm assuming it has kicked in but I'm really tired but full of anxiety... How much more longer will the "high" be gone?

Anxiety: I understand your concern.
Benadryl can cause drowsiness and tiredness.
Benadryl Allergy & Cold can cause excitability, anxiety, restlessness and insomnia.
“Feeling high” can be due to Cocaine and Amphetamines.
Stresses of relationship with parents and girlfriend; separation, peer pressure to use alcohol and drugs;, and to establish your Identity can cause Anxiety.
See Psychiatrist for Therapy ...Read more

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How can Benadryl (diphenhydramine) and Xanax differ when it comes to treating anxiety?

How can Benadryl (diphenhydramine) and Xanax differ when it comes to treating anxiety?

Very different med: Xanax and Benadryl (diphenhydramine) are two very different medications. Xanax is an anti anxiety medication approved for the treatment of anxiety. It is in the benzodiazepine class of medication so there is a risk of tolerance and withdrawal symptoms that lead to dependence. Benadryl (diphenhydramine) is an anti histamine approved for the treatment of allergy symptoms. It primarily produces drowsiness which can cover anxiety. ...Read more

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If I take Benadryl (diphenhydramine) before getting on a plane, will the sedation from it help with my plane anxiety?

If I take Benadryl (diphenhydramine) before getting on a plane, will the sedation from it help with my plane anxiety?

Causes drowsiness: Might suggest this be dealt with like one handles stage fright. Try a beta-blocker like propanalol or timolol. Another choice, alprazolam, which could keep you more awake. Talk to your doc, as these approaches are all generic and relatively cheap. ...Read more

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Why can hydroxyzine be used for anxiety but not diphenhydramine? Both are antihistamines, one derived from the other, correct?

Not same effects: In same class of drugs as Diphenhydramine but has antagonistic effects on several receptor sites in the brain which means it works to treat anxiety, mild depression and unhealthy thought processes. ...Read more

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I'm having a bad anxiety attack and I want more than my usual dose of xanax. Would it be okay to take a Benadryl (diphenhydramine) or two with it?

I'm having a bad anxiety attack and I want more than my usual dose of xanax. Would it be okay to take a Benadryl (diphenhydramine) or two with it?

Consult with MD: I can answer this question for my individual patients (whom I know well). However, this is really an important question for you to address with your physician. I am afraid that by telling you how to take your meds that I would be providing medical treatment (which only your providers should do). Take care. ...Read more

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Hypersensitivity to meds, kids dose of Benadryl (diphenhydramine) too much. Took 5mg Celexa for anxiety- bad heightened anxiety, stopped. Any meds with less s.effects?

Possible: Each child can respond differently to meds. Sometimes it's hit or miss until u find the right one. Ask your MD for MillineumPGT saliva test - genitic test to see what meds have higher potential side effects. Ask about buspar (buspirone) if mild anxiety. Try chamomile calming teas twice a day with melatonin at night. May consider visit with therapist to learn anxiety relaxation exercises. Good luck! ...Read more

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I am on 50mg of Zoloft (sertraline) for anxiety and wondering if I can take diphenhydramine to help me sleep. I worry about them interacting but I can't sleep: (?

I am on 50mg of Zoloft (sertraline) for anxiety and wondering if I can take diphenhydramine to help me sleep. I worry about them interacting but I can't sleep: (?

Yes, you may take it: Start at 25 mg with the benadryl (diphenhydramine). Consider also using melatonin instead at a dose of 3 mg taken two hours before your desired sleep time. Also practice good sleep hygiene which you can find here on healthtap under dr heidi fowler's answers or at
counselingservice. Vassar. Edu/docs/sleep%20hygeine%20...
Good sleep hygiene handout the most common cause of insomnia is a change in your daily routine. ...Read more

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Benadryl (diphenhydramine) mthly with my IVIG. Always makes me SO TIRED! Am on klonopin 4 anxiety. Wondering if Benadryl (diphenhydramine) is like klonopin & I should take that instead?

Benadryl (diphenhydramine) mthly with my IVIG. Always makes me SO TIRED! Am on klonopin 4 anxiety. Wondering if Benadryl (diphenhydramine) is like klonopin & I should take that instead?

Advice: The Benadryl (diphenhydramine) is present to combat an infusion reaction, such as an allergic response. There are other antihistamines which do not promote these adverse effects, and seems to be no reason to not try these. Klonopin would not be a useful substitute. ...Read more

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I alternate between Benadryl (diphenhydramine) and klonopin (for sleep) is it safe to take klonopin for anxiety morning after taking a Benadryl (diphenhydramine) for sleep?

Cannot fully endorse: Your information is of concern, as you describe issues with both sleep and anxiety and they may well relate. However, sounds like this may be getting more complex. You obviously have a sleep disorder, and may well need help with the anxiety. Please see a sleep specialist, and perhaps a psychiatrist, as there may be more success with an alternative approach. ...Read more

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Should I take Benadryl (diphenhydramine hcl) for my poison ivy even though I suffer from anxiety?

Should I take Benadryl (diphenhydramine hcl) for my poison ivy even though I suffer from anxiety?

Other antihistamine: The main reason to take antihistamines for poison ivy is to decrease the itching. There is risk of central nervous system effects with benadryl (diphenhydramine). Potentially it could aggravate anxiety disorders. An antihistamine that does not cross over into the brain like Benadryl (diphenhydramine) is Allegra (fexofenadine). It will still help with the itching. ...Read more

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Hubby got scary CT results and I have had anxiety hives for 2 days. They come and go. Already on. 5mg Klonopin 3x's a day. Can I take Benadryl (diphenhydramine) or??

Moderate interaction: Benedryl can increase the sedating effects of Klonopin (clonazepam). Some people exerience dizziness and confusion with this combination, so it would be important to avoid driving or performing tasks that require good concentration. Zyrtec is indicated for chronic hives, and may be less sedating than Benedryl. ...Read more

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History of anxiety, found hive on arm yesterday, two hives on leg this am. Very anxious, history ofs easonal allergies. I took 2 motrin and 2 benadryl (diphenhydramine)?

History of anxiety, found hive on arm yesterday, two hives on leg this am. Very anxious, history ofs easonal allergies. I took 2 motrin and 2 benadryl (diphenhydramine)?

Hard to tell: Hives can be triggered by many things including stress. However drugs, foods, or viral infection can cause acute hives as well. If the problem is not severe and goes away after 6 wks, just try antihistamine if the trigger cannot be identified. See your doctor or allergist if the problem extends beyond 6 weeks or not responded well to anithistamine. ...Read more

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I take 40 mg of Vyvanse for ADHD and 20mg of prozac for anxiety and I think 20 mg of olmeprazole for reflux. Is it safe to take Advil and Benadryl (diphenhydramine)?

I take 40 mg of Vyvanse for ADHD and 20mg of prozac for anxiety and I think 20 mg of olmeprazole for reflux. Is it safe to take Advil and Benadryl (diphenhydramine)?

Advil (ibuprofen) a good choice: On your current medications you should have no problem taking Advil (ibuprofen) at usual and recommended dose.

At higher doses of any of these medications, one could get the serotonin syndrome (which has been written about in this column. ...Read more

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Dr. Oz, I can't sleep, so I'm taking an over-the-counter sleep aid called diphenhydramine 50mg & red wine, will this kill me? I have not been able to sleep for 2 years now because of my disability. I have arthritis, anxiety and a problem with my wrist. Th

Dr. Oz, I can't sleep, so I'm taking an over-the-counter sleep aid called diphenhydramine 50mg & red wine, will this kill me? I have not been able to sleep for 2 years now because of my disability. I have arthritis, anxiety and a problem with my wrist. Th

Hi,: Hi, this isn't dr. Oz. You don't note how much red wine. A moderate amount of red wine and 50mg of diphehydramine should not kill you. However, this is not a good cocktail for sleep. Over the counter sleep aids that contain antihistamines can eventually lead to rebound insomnia. Alcohol is the number one cause for insomnia in this country. Over time, it can cause problems with sleep.
Try going to bed at the same time each night. Use the bedroom only for sex or sleep (no tv, radio or other distractions). It is best to have a very quiet and dark bedroom. Avoid caffeine in the evening. Avoid large evening meals or late dinners. Limit exercise to late afternoon or earlier. Avoid napping. Limit alcohol use (or don't drink). Try to encorporate a calming routine at night (like taking a warm bath with lavender). Consider drinking warm milk or camomile tea at bedtime. Melatonin can be very helpful for sleep.
Medical acupuncture can be used in the treatmet of arthritis, anxiety and pain. It is effective, safe and there are no medication interactions. It is not covered by all insurance plans however. Take care. ...Read more

Dr. John Chiu
1,047 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more