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Doctor insights on: Diphenhydramine Drug Interactions

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Are there any drug interaction with inderal (propranolol) and diphenhydramine?

Are there any drug interaction with inderal (propranolol) and diphenhydramine?

No: There are no significant interactions between these two drugs. They are safe to take together. ...Read more

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Dr. Abraham Jaskiel
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Drug Interaction (Definition)

When the combination of two agents cause an effect, intended or unintended, that would not have otherwise ...Read more


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Are there any drug interactions? I took 3mg melatonin at 1:30am, Aller-tec at 10:30 am, Lansoprazol at 11:30, and Benadryl(allergic reaction) at 12pm

Are there any drug interactions? I took 3mg melatonin at 1:30am, Aller-tec at 10:30 am,  Lansoprazol at 11:30, and Benadryl(allergic reaction) at 12pm

Nighty night: The worst thing that'lll happen with those meds is that you'll probably get some much needed rest! LOL....I know cuz I've 4 teenagers of my own. At least you've got a good reason to be sleeping with the melatonin and Benadryl (diphenhydramine). That should put you down for a little snooze. Otherwise, you should be good. Do you really need all those drugs? Your pharmacist can also help you with drug interactions ...Read more

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Can some drug you with benadryl (diphenhydramine)?

Yes: One can be drugged with anything. Benadryl (diphenhydramine) can cause drowsiness, dizziness, confusion, nausea, urinary retention and more if given high doses or to susceptible individuals. ...Read more

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What type of drug is Benadryl (diphenhydramine) and what are its uses?

What type of drug is Benadryl (diphenhydramine) and what are its uses?

Benadryl (diphenhydramine): It is a first generation antihistamine. Very powerful but has side effects that many 2nd generation otc antihistamines do not have. Among it uses are for allergies and in otc sleep aides. ...Read more

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Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

Are there any interactions between diphenhydramine and l-theamine? Can both be taken together safely in recommended amounts for sleep?

No: I am not sure what l-theanine is. However, the only dietary supplements/herbals i know of which should be avoided when taking Diphenhydramine are valerian, st. John's wort, kava kava, and gotu kola; as the combination may enhance CNS depression. I am doubtful that whatever l-theanine is will compound any sedative effects you may experience with Diphenhydramine alone. ...Read more

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Is it safe to take Pseudophedrine and Diphenhydramine together? Medscape says significant interaction but other sources say no interaction.

Is it safe to take Pseudophedrine and Diphenhydramine together? Medscape says significant interaction but other sources say no interaction.

OK to take together: Diphenhydramine is benadryl, (diphenhydramine) which is an antihistamine. Many antihistamines are taken together with decongestants such as pseudoephedrine. Diphenhydramine can help itching, sneezing, swelling, whereas Pseudoephedrine can help nasal congestion. Common antihistamine/decongestant combos include loratadine-D, cetirizine-D, fenofexadine-D. ...Read more

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Is diphenhydramine a type of anti inflamatory drug?

Is diphenhydramine a type of anti inflamatory drug?

Not really: Diphenhydramine blocks histamine effects and as such blocks inflammation but not in the same sense as asa, advil, aleve (naproxen) or steroids which have multiple anti inflammatory effects for arthritis, injury, etc. ...Read more

Dr. John Chiu
1,011 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more