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Doctor insights on: Diphenhydramine And Oxycodone

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Would 2 pills of tylenol, 1 tramadol, 2 advil, 1 oxycodone, 4 benadryl, 3 midnite sleep aid and 2 melatonin be bad or just put me to sleep for awhile?

Would 2 pills of tylenol, 1 tramadol, 2 advil, 1 oxycodone, 4 benadryl, 3 midnite sleep aid and 2 melatonin be bad or just put me to sleep for awhile?

YES - DANGEROUS!: This is way too much medication to take all at once, and could put you in grave danger - including potential liver/kidney damage, or worse - death. If you are having trouble sleeping, then talk to your doctor about this, and they can work on establishing an effective treatment plan. Work on your stress factors. Eliminate caffeinated beverages before bed. Best wishes. ...Read more

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Dr. Christopher Crosby
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Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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I just had breast reduction today and they put me in oxycodone and a z pack I am very itchy i can't sleep my whole body itches can I take benadryl?

I just had breast reduction today and they put me in oxycodone and a z pack I am very itchy i can't sleep my whole body itches can I take benadryl?

Yes: Benadryl may help the itching however, the itching may be coming from a reaction to the oxycodone or the zpak. You should check with your doctor and see what he/she advises. ...Read more

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Dr. Christopher Crosby
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Can you really die from an overdose of diphenhydramine?

Can you really die from an overdose of diphenhydramine?

Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read more

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What amount diphenhydramine is an overdose?

What amount diphenhydramine is an overdose?

It depends: Diphenhydramine was a major cause of seizures reported to a poison center. At a dose of 7.5mg/Kg (a total dose of 500 mg [20 OTC tablets] for a 150 pound person) many p0eople will develop severe reactions. In doses over 1g (40 tablets) the drug may be lethal. ...Read more

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Dr. Christopher Crosby
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Had 100mg of diphenhydramine last night at 10PM. Is it normally safe to take that dose two nights in a row?

Yes: THe maximum daily dosage of diphenhydramine is 400mg/day However, the recommended dosage of the medication for insomnia is 50mg at night. Would recommend to reduce the dosage to 50mg at night Please see your doctor if still have issues with insomnia. ...Read more

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Is diphenhydramine adictave?

Is diphenhydramine adictave?

No: The antihistamine is does not have addictive qualities. Yet a person can become habit driven to continue any product/medication/coffee/food etc.Habituation is a strong force in ones life to continue past patterns. If stopped, a longing for that product can be quite strong, but it does not produce the physical addiction entails. ...Read more

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What are the effects of diphenhydramine od?

What are the  effects of diphenhydramine od?

Dangerous Effects: Although death by Diphenhydramine overdose is uncommon, dangers associated with an overdose include cardiac arrhythmias, delirium, respiratory suppression, short-term memory loss, and urinary retention. If you suspect Diphenhydramine overdose, contact emergency services (911). There is an antidote that can be administered by medical professionals in the emergency room. ...Read more

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Dr. Michael Rupp
944 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Clifford Gevirtz
645 doctors shared insights

Oxycodone (Definition)

Schedule ii controlled medication. Opioid (semi-synthetic) used ...Read more


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Dr. Christopher Crosby
Board Certified, Dermatology
10 years in practice
92K people helped
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