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Doctor insights on: Diphenhydramine And Oxycodone

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Dr. Felecia Sumner
Board Certified, Family Medicine
4 years in practice
763K people helped
1

1
Would 2 pills of tylenol, 1 tramadol, 2 advil, 1 oxycodone, 4 benadryl, 3 midnite sleep aid and 2 melatonin be bad or just put me to sleep for awhile?

Would 2 pills of tylenol, 1 tramadol, 2 advil, 1 oxycodone, 4 benadryl, 3 midnite sleep aid and 2 melatonin be bad or just put me to sleep for awhile?

YES - DANGEROUS!: This is way too much medication to take all at once, and could put you in grave danger - including potential liver/kidney damage, or worse - death. If you are having trouble sleeping, then talk to your doctor about this, and they can work on establishing an effective treatment plan. Work on your stress factors. Eliminate caffeinated beverages before bed. Best wishes. ...Read more

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Dr. Buck Parker
Board Certified
11 years in practice
415K people helped
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Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Dariush Vaziri
Board Certified, Breast Surgery
41 years in practice
318K people helped
2

2
I just had breast reduction today and they put me in oxycodone and a z pack I am very itchy i can't sleep my whole body itches can I take benadryl?

I just had breast reduction today and they put me in oxycodone and a z pack I am very itchy i can't sleep my whole body itches can I take benadryl?

Yes: You may be allergic to the medications you are taking. It is OK to take Benadryl but cal your prescribing physician and inform her/him of your symptoms. Your meds may have to be changed. ...Read more

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Dr. Buck Parker
Board Certified
11 years in practice
415K people helped
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Dr. Steven Machtinger
Board Certified, Allergy and Immunology
38 years in practice
7M people helped
3

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Can you really die from an overdose of diphenhydramine?

Can you really die from an overdose of diphenhydramine?

Yes.: There are numerous studies & case reports in the medical literature of deaths due to either accidental or intentional overdoses of Diphenhydramine (benadryl). The drug has a high therapeutic index meaning the dose needed to cause death is many times higher than that needed to produce beneficial effects. Its always a good idea to be cautious with all drugs - prescribed, otc, herbal or homeopathic. ...Read more

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Dr. Joram Seggev
Board Certified, Allergy and Immunology
1M people helped
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4
What amount diphenhydramine is an overdose?

What amount diphenhydramine is an overdose?

It depends: Diphenhydramine was a major cause of seizures reported to a poison center. At a dose of 7.5mg/Kg (a total dose of 500 mg [20 OTC tablets] for a 150 pound person) many p0eople will develop severe reactions. In doses over 1g (40 tablets) the drug may be lethal. ...Read more

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Dr. Buck Parker
Board Certified
11 years in practice
415K people helped
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Dr. Charles Gordon
Board Certified, Adolescent Medicine
191K people helped
5

5
Can I take 75mg of Diphenhydramine HCI?

Depends: Diphenhydramine is the generic name of an antihistamine whose brand name is Benadryl. Drugs are usually dosed on body weight and how quickly they are usually metabolized. For this one usually every 6 hours. Most common side effect is tiredness (2 out of 3) but 1 out of 3 speed up. Never a dull moment in medicine if your always thinking about what you're doing. PS- you did not mention your weight. ...Read more

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Dr. John Chiu
Board Certified, Allergy and Immunology
51 years in practice
21M people helped
6
Dr. Jose luis Hernandez
Board Certified, Internal Medicine
6 years in practice
84K people helped
7

7
Had 100mg of diphenhydramine last night at 10PM. Is it normally safe to take that dose two nights in a row?

Yes: THe maximum daily dosage of diphenhydramine is 400mg/day However, the recommended dosage of the medication for insomnia is 50mg at night. Would recommend to reduce the dosage to 50mg at night Please see your doctor if still have issues with insomnia. ...Read more

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Dr. John Chiu
Board Certified, Allergy and Immunology
51 years in practice
21M people helped
8
Dr. Susumu Inoue
Board Certified, Pediatrics
51 years in practice
354K people helped
9
Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
10

10
Is diphenhydramine adictave?

No: The antihistamine is does not have addictive qualities. Yet a person can become habit driven to continue any product/medication/coffee/food etc.Habituation is a strong force in ones life to continue past patterns. If stopped, a longing for that product can be quite strong, but it does not produce the physical addiction entails. ...Read more

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Dr. Michael Rupp
958 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Clifford Gevirtz
647 doctors shared insights

Oxycodone (Definition)

Schedule ii controlled medication. Opioid (semi-synthetic) used ...Read more


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Dr. Buck Parker
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11 years in practice
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