Doctor insights on:
Specific & limited: Pregnenolone is an adrenal hormone made from cholesterol, and is the pre-cursor for sex-steroid hormones. It is said to 'improve mood, ' but no strong data support. To my knowledge there is no role for it's use as a supplement. Aromatase inhibitors are for treatment of some breast cancers; they're also used off-label for ovulation induction in women. No other appropriate uses to my knowledge. ...Read more
Dihydrotestosterone is the byproduct of testosterone when it is transformed by a process called 5alpha reductase. This is what can cause male pattern baldness and prostate enlargement. This is also why saw palmetto is used for a healthy prostate as it is a 5 Alpha reeductase inhibitor ...Read more
Equally effective: Both are equally effective in supplementing testosterone in hypogonadal men and are approved by the fda for such. It's a matter of personal preference as well as formulary coverage. Risk of Androderm is adhesive dermatitis or rash from patch. Risk from AndroGel is transfer to partner or kids. These specific risks are in addition to general risks associated w/testosterone in any other shape or form. ...Read more
Are androstadiene, androsta (pro-testosterone compound) and hydroxyandrostendione considered as steroids?
Steroids : Yes, they all have the steroid structure. It is a chemical structure that starts with cholesterol. ...Read more
Hormones: All testosterone products are reliable - there are 20 or more options. That said, testosterone by injection is substantially less expensive than anything else. Most often your doctor will teach you how to take your injection and will have you come back in two weeks to see if you (or a significant other) can properly give the injection. The timing between injections will vary a bit. ...Read more
Erectile dysfunction, male used revivogen shampoo inhibits testosteron to dht conversion for more than 3 years & premature ejaculation_what treatment?
When a male uses a DHT blocker does that mean that instead of excess testosterone converting to DHT it will convert to estrogen? Is blocking DHT safe?
Yes (maybe): As you noted, 5ARIs (alpha reductase inhibitors) block conversion of Testosterone into Dihydrotestosterone. However, as a consequence, you might convert T into Estradiol (estrogen). This is real concern w/potential side effects such as gynecomastia, loss of libido, erectile dysfunction listed in small print for drug. There have also been reports of infertility. Only u can decide if benefit > risk ...Read moreSee 1 more doctor answer
Equally effective: Both products are equally effective in supplementing hypogonadal men. Unfortunately, i don't believe testoderm is available in us anymore. Other options in the us besides Androderm include androgel, axiron, fortesta, striant, testim, testopel & injectable testosterone. Don't forget that testosterone can also be compounded. If you want to father children, you'll need to avoid these products. ...Read moreSee 1 more doctor answer
Neither: Androgel & Androderm (along w/axiron, fortesta, striant & testim) are just different forms of testosterone. None are better for everyone. It all depends upon cost to you (think insurance or lack thereof) as well as route & frequency of application. Of course, there's always injectable testosterone, too, which is typically cheapest but it's a shot, at least once weekly. ...Read moreSee 1 more doctor answer
Erectile Dysfunction: Men w/erectile dysfunction often use some form of Alprostadil if they don't respond to oral pde-5 inhibitors like cialis, levitra, (vardenafil) staxyn, stendra & viagra. Men w/ed who also take nitrates are forbidden from taking pde-5 inhibitors and thus must use Alprostadil or some other therapeutic ed option. Alprostadil can be placed intraurethral or injected intracavernosal. Ask your family doc for options. ...Read more
How safe is herbal "Saw palmetto" it decreases the conversion of testosterone to DHT. Is this process safe? What is DHT for? Is blocking DHT safe?
Gel vs injection: Testosterone replacement therapy, or trt, can be done with shots (typically administered every 2-3 weeks) or a daily application of a gel or cream. Both methods are fda-approved. Shots increase t levels rapidly and taper off slowly until the next shot. The topical method, in my opinion, is superior in that it mimics more closely how t is secreted naturally by your body. ...Read moreSee 1 more doctor answer
Moot point in US: Testoderm is no longer available in the us. Besides androderm, options include androgel, axiron, fortesta, striant, testim, testopel & injectable testosterone. Decision is personal one & depends upon cost (formulary), tolerance for injections/implants/buccal patch, tendency to develop adhesive dermatitis, risk of transference to loved ones, etc. If fertility is an issue, avoid all these products. ...Read more
Yes: Testosterone is broken down into Dht & Estradiol (e2). Too much Dht is associated w/hair loss & prostate enlargement. Too much e2 is associated w/gynecomastia, eg nipple sensitivity and/or male breast development (moobs). Different medications can stop metabolism of t but can also upset balance (think of a seesaw). So if Dht goes down, e2 might go up. And vice versa. Talk to doc & monitor levels. ...Read more
Testosterone: Over the counter concoctions may contain testosterone precurrsors but there is little effect on serum testosterone. A multi-million dollar industry which preys on the common male desire to be "more masculine". Save your money. If your testosterone level is tested and is indeed low for your age, a qualified urologist or endocrinologist may prescribe testosterone supplimentation. ...Read more
Yes: Typically, these are all metabolized the samer. ...Read more
Safer Med: Gel is safer compared to injection. But if you are looking for more effective one, it will be injection. ...Read more
What's worse for increasing DHT levels while doing transdermal testosterone or injectable testosterone?
Transdermal: Enzyme that converts testosterone into Dht (too much is associated w/hair loss & enlarged prostate) is found in hair follicles. Typical branded topical testosterone is very dilute and requires application over larger surface area, thus increasing dht. Injectable t is less likely to do so unless you spike levels by injecting once monthly (or your body has propensity to convert t into dht). ...Read more