Doctor insights on:
Dihydrotestosterone Side Effects
Would using Dihydrotestosterone (DHT)blockers like an Antiandrogen to block DHT's from affecting hair follicle growth have unpleasant side effects?
Dihydrotestosterone is the byproduct of testosterone when it is transformed by a process called 5alpha reductase. This is what can cause male pattern baldness and prostate enlargement. This is also why saw palmetto is used for a healthy prostate as it is a 5 Alpha reeductase inhibitor ...Read more
Antiandrogens Lupron (leuprolide): For example is used to treat certain types of advanced prostate cancer. Castration is very effective, but only recommened as part of gender reversal, or with advanced prostae cancer. Taking Estrogens or large quantities of tofu, which has an estrogenic effect, can also reduce Dht levels. However, you probably need to explain &/or discuss why anyone would wish to reduce their Dht levels. ...Read more
DHT: Dihydrotestosterone is the byproduct of testosterone when it is transformed by a process called 5alpha reductase. This is what can cause male pattern baldness and prostate enlargement. This is also why saw palmetto is used for a healthy prostate as it is a 5 Alpha reeductase inhibitor and reduces the reaction. ...Read more
Yes?: Dihydrotestosterone (dht) is the bio-active form of testosterone(t). Blocking t to Dht by 5-alpha reductase inhibitors such as Finasteride or Dutasteride will decrease psa by some 50%. So, we can say more Dht may cause psa elevation. But, still remember, to a great extent, a healthy body has all bio-feed-back automation to regulate the balance of substances of metabolism. Then, if any, high dht... ...Read moreSee 2 more doctor answers
Why do u want more?: Testosterone is metabolized (broken down) into Dht & Estradiol (e2). Testosterone is anabolic (makes muscles grow). Dht is androgenic (makes you more male). But too much Dht can also lead to hair loss and prostate enlargement. So we don't typically try to raise Dht (although if you take an aromatase inhibitor to shut down e2, you might raise Dht via seesaw effect), rather we lower Dht via 5ari. ...Read more
Yes they can: It is too late if you wait until after puberty. We use 50 mg of Depo-Testosterone by intramuscular injection monthly for 2 - 4 injections depending on response. Hormone is given in a relatively small dose, if he is a big kid, also widely spaced to avoid stunting his growth by so called epiphyseal fusion of his bones. ...Read more
Lucky, I guess!: Sorry, i'm feeling flippant tonight. Testosterone is metabolized (broken down) into Dht & Estradiol (e2). How much is "wasted" is an individual matter (we don't have much natural control). We can try to affect the ratio of wastage, eg dht:e2, by exercising & losing fat, which might decrease e2 & increase Dht (think of a seesaw). If you're losing hair or have enlarged prostate, 5ari will lower dht. ...Read more
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